How microbiota — microbes that live on human surfaces — impact cancer development and therapy has become an expansive area of research.
Kenyan teenage girls who were given menstrual cups were less likely to acquire certain kinds of vaginal infections and were more likely to have a healthy vaginal microbiome, found a study by University of Illinois Chicago researchers.
A new study investigated the role of the genes in individual switchgrass plants in determining the composition of the bacterial communities associated with the plants’ roots.
Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study. In the first randomized study of its kind, published in the science journal mBio, a team of researchers found the process, known as vaginal seeding, definitively engrafted new strains of maternal bacteria in the babies’ bodies.
Article title: Commensal microbiota regulate renal gene expression in a sex-specific manner Authors: Brittni N. Moore and Jennifer L. Pluznick From the authors: “This report demonstrates that renal gene expression is modulated by the microbiome in a sex- and tissue-specific…
A new study by researchers at Children’s Hospital of Philadelphia (CHOP) has demonstrated that IgA acts as a “tuner” that regulates the number of microbes the body sees every day, restraining the systemic immune response to these commensal microbes and limiting the development of systemic immune dysregulation.
Article title: Absence of gut microbiota impairs depletion of Paneth cells but not goblet cells in germ-free Atoh1lox/lox VilCreERT2 mice Authors: Mohsin Hassan, Oriol Juanola, Stefania Huber, Philipp Kellmann, Jakob Zimmermann, Edoardo Lazzarini, Stephanie C. Ganal-Vonarburg, Mercedes Gomez de Agüero,…
University of Illinois researchers found that people who ate avocado daily as part of a meal had a greater abundance of gut microbes that break down fiber and produce metabolites that support gut health. Study participants consumed their normal diets…
Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).
A world-first study from the University of South Australia shows that while Bd can significantly reduce in captive frogs, captivity can have negative consequences for the frogs’ protective skin microbiota, providing new insight into diversity management.
The study findings suggest possibilities for developing new drugs that replicate or build on A. muciniphila’s immuno-modulatory activity.
The work provides a model for using traditional techniques to pinpoint how other members of the gut microbiome act on the body.
New research in rats finds a diet high in the fiber inulin offered a protective effect against the damage of a high-salt diet. The research will be presented this week at the American Physiological Society and American Society for Nephrology Control of Renal Function in Health and Disease conference
New research in rats finds specific bacteria populations in the mouth and on the skin may be beneficial in blood pressure regulation. The first-of-its-kind study is published ahead of print in Physiological Genomics.
Researchers reporting in ACS’ Journal of Agricultural and Food Chemistry have found that levels of volatile, sulfurous compounds are similar in parent-child pairs, suggesting shared oral microbiomes. They also found that high levels cause children to dislike the vegetables.
Gut reaction: Cornell researchers “humanized” mice with microbiota from three global populations and found that microbial differences alone can impact immune responses.
Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.
Bacteria’s role in gut health has received a lot of attention in recent years. But new research publishing in Nature shows that fungi—another microorganism that lives within us—may be equally important in health and disease. Fungi thrive in the healthy gut, but when interactions with the immune system are off-balance, they cause intestinal damage that may contribute to gastrointestinal disease. Additional investigation demonstrate that vaccines could be developed as therapeutics to improve gut health.
Babies born by cesarean section don’t have the same healthy bacteria as those born vaginally, but a Rutgers-led study for the first time finds that these natural bacteria can be restored.
Research published in Nature reveals insights into how the body maintains balance with “good” gut bacteria that allows these microbes to flourish in the intestine but keeps them out of tissues and organs where they’re not supposed to be.
Early life exposure to antibotics in utero and through mother’s milk disrupts beneficial gut bacteria, compromising T-cell development, Rutgers research shows
Study demonstrates how a subset of common gut bacteria renders mice resistant to viral infections.
Researchers at Rutgers University, the Copenhagen Prospective Studies on Asthma in Childhood and the University of Copenhagen have described for the first time how delivery by caesarean section interferes with a baby’s ability to obtain beneficial germs from the mother’s microbiome, and how this can lead to early childhood asthma.
UC Davis researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre- inflammatory bowel disease. This combination shuts down the mitochondria in cells of the colon lining, leading to gut inflammation. Mesalazine can help restart the mitochondria and treat pre-IBD condition.
A new study finds antibiotic exposure during crucial developmental periods in early childhood alters digestive tract nerve function and bacterial colonies. The study is published in the American Journal of Physiology-Gastrointestinal and Liver Physiology.
The Biocodex Microbiota Foundation, an organization founded by Biocodex and committed to inspiring scientific projects that investigate the implication of microbiota in human health, has announced the open call for applications for its annual US research grant, now in its fourth year.
A new study finds that a Rutgers-driven proposal to create a “microbial Noah’s ark” to protect the long-term health of humanity is feasible and should move forward into a pilot project phase.
The Memorial Sloan Kettering – Hackensack Meridian Health Partnership has formed an Immunology Research Collaboration, through which researchers can apply for funding to support innovative investigations to explore the power of the immune system and ways it may be harnessed to fight cancer. Three researchers’ projects were selected in 2020 for funding support.
Article title: Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit Authors: Mattea Müller, Gerben D.A. Hermes, Emanuel E. Canfora, Hauke Smidt, Ad A.M. Masclee, Erwin G. Zoetendal, Ellen E. Blaak From…