A new study published in Clinical Gastroenterology and Hepatology led by Maria T. Abreu, M.D., professor of medicine and professor of microbiology and immunology at the University of Miami Miller School of Medicine, found that eating diets low in fat and high in fiber may improve the quality of life of patients with ulcerative colitis (UC) — even those in remission.Read more
Researchers at Washington University School of Medicine in St. Louis have identified a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.Read more
Investigators at the Case Western Reserve University School of Medicine discovered that blocking interleukin-1α (IL1α), a protein that controls inflammation in the gut, markedly decreases the severity of intestinal inflammation in a mouse model of Crohn’s disease (CD).Read more
Scientists have made genetic data publicly available for bacteria that might be lurking inside the gut walls of patients chronically affected with severe Crohn’s disease.
By studying a surgically removed, damaged bowel from a patient, researchers were able to culture bacteria from a special form of microscopic lesions that they earlier discovered and that can be present within the gut wall of the inflamed bowel in Crohn’s disease. After growing the bacteria in their laboratory, they chose one representative species, and performed a complete genome sequence analysis that could hold clues into how the slow and damaging microlesions form.