New Cedars-Sinai Study Pinpoints Why Some Injured Kidneys Do Not Heal

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in the peer-reviewed journal Science, could lead to the development of noninvasive tests to detect kidney scarring and, eventually, new therapies to reverse the condition.

Why the Top Cause of Death for Women Has Been Ignored

Experts at the Smidt Heart Institute at Cedars-Sinai who have studied progress made over decades of research say there’s still a long way to go before medical science fully understands how heart disease is different in women than men.

Postpartum heart risk: Tips for young moms who may be unaware of long-term dangers

Young women with healthy hearts may be unaware they face elevated risks of developing heart disorders after becoming pregnant. Even worse, the issue may go undetected for years after giving birth because symptoms may mimic those of pregnancy. Dr. Rina…

Enzyme in T Cells Worsens Salt-sensitive Hypertension and Related Kidney Damage

Article title: Functional NADPH oxidase 2 (NOX2) in T cells amplifies salt-sensitive hypertension and associated renal damage Authors: Samuel D. Walton, John Henry Dasinger, Emily C. Burns, Mary Cherian-Shaw, Justine M. Abais-Battad, David L. Mattson From the authors: “The results…

Exercise May Prevent Stress-induced Hypertension through Regulation of Brain-bone Marrow Interaction

Article title: Impact of exercise on brain-bone marrow interactions in chronic stress: potential mechanisms preventing stress-induced hypertension Authors: Thu Van Nguyen, Ko Yamanaka, Keisuke Tomita, Jasenka Zubcevic, Sabine S. S. Gouraud,  Hidefumi Waki From the authors: “Our findings provide new…

High blood pressure in your 30s is associated with worse brain health in your 70s

New research from the UC Davis School of Medicine shows high blood pressure in early adulthood is associated with worse brain health in late life — especially for men. The results suggest that treating hypertension in young and middle-aged adults may help prevent dementia and Alzheimer’s disease.

Keep Your Heart Strong with these 3 Foods. Expert Tips for February: American Hearth Month

Heart disease is the leading cause of death in the United States for both men and women, with half of all Americans (47%) qualifying for at least one of the three key risk factors (high blood pressure, high cholesterol, smoking cigarettes). Keep Your Heart Strong with these 3 Foods. Expert Tips for February: American Hearth Month
Heart disease is the leading cause of death in the United States for both men and women, with half of all Americans (47%) qualifying for at least one of the three key risk factors (high blood pressure, high cholesterol, smoking cigarettes). Good news: You can manage two of these risk factors.

Researchers ID Kidney Pathway Involved with Autoimmune-related Hypertension in Female Mice

Article title: Renal TLR-7/ TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension Authors: Sarika Chaudhari, Bradley M. D’Souza, Jessica Y. Morales, Cassandra M. Young-Stubbs, Caroline G. Shimoura, Rong Ma, Keisa W. Mathis From the authors:…

Flozin Drugs Lower Salt-Induced Hypertension, Maintain Circadian Rhythm in Rats

Article title: SGLT2 inhibition effect on salt-induced hypertension, RAAS and Na+ transport in Dahl SS rats Authors: Olha Kravtsova, Ruslan Bohovyk, Vladislav Levchenko, Oleg Palygin, Christine A. Klemens, Timo Rieg, Alexander Staruschenko From the authors: “The main findings of the…

Rat Model of Preeclampsia Gives new Insight into Immunological Changes during Pregnancy

Article title: Immunological comparison of pregnant Dahl salt-sensitive and Sprague-Dawley rats commonly used to model characteristics of preeclampsia Authors: Erin B. Taylor, Eric M. George, Michael J. Ryan, Michael R. Garrett, Jennifer M. Sasser From the authors: “The current study…

Intrauterine Growth Restriction in Rats Causes Long-term Increases in Offspring’s Blood Pressure, Impairs Renal Artery Vascular Tone

Article title: Vascular tone regulation in renal interlobar arteries of male rats is dysfunctional after intrauterine growth restriction Authors: Jenny Voggel, Lubomir Lubomirov, Felix Lechner, Gregor Fink, Eva Nüsken, Maria Wohlfarth, Gabriele Pfitzer, Kija Shah-Hosseini, Martin Hellmich, Miguel A. Alejandre…

NYU Langone Health Named Coordinating Center for American Heart Association Health Equity Research Network to Prevent Hypertension in Black Communities

As part of a $20 million award from the America Heart Association, NYU Grossman School of Medicine has been named as the coordinating center for a new collaboration between eight universities to prevent hypertension and reduce racial inequities in cardiovascular disease outcomes in Black communities.

Association between Hypertension and Gut Microbiome Imbalance during Pregnancy May Lead to New Preeclampsia Treatments

Article title: Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension Authors: Jeanne A. Ishimwe, Adesanya Akinleye, Ashley C. Johnson, Michael R. Garrett, Jennifer M. Sasser From the authors: “These results reveal an…

A New Beat Offers Free Online Seminar Examining Disparities in Cardiovascular Care During Heart Month

The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) is offering a complimentary online seminar, “Tackling Disparities in CV Care: A Closer Look at Hypertension and Heart Failure” on Friday February 26, 2021. The program is part of a joint initiative called A New Beat which advocates for women and minorities rising as leaders in cardiology. It aims to foster careers of female and minority cardiologists, who can be poised to improve access to quality care for underserved populations.

CRF Offers Free Online Seminar to Help People Jump-Start their Heart Health During Heart Month

The Cardiovascular Research Foundation (CRF) will hold a free online seminar, The Big Three: High Blood Pressure, High Cholesterol, and Diabetes, at 12:00 PM ET on February 22, 2021 hosted by Drs. Nisha Jhalani and Sonia Tolani, cardiologists from NewYork-Presbyterian/Columbia University Irving Medical Center. The seminar is part of a series of “Mini Med Schools” conducted by the CRF Women’s Heart Health Initiative (WHHI), which empowers women with everyday tools they can use to defy heart disease.

Mount Sinai Researchers Find That Where People Live Can Impact Their Risk for Common Chronic Conditions Including High Blood Pressure and Depression

The researchers found that a persons’ place of residence substantially influences their risk of uncontrolled chronic disease including high blood pressure and depression

Exposure to Vitamin D in the Womb Might Minimize Risk of High Blood Pressure for Children Born to Mothers with Preeclampsia

Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy—but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb.

Prevent Severe COVID Symptoms With Lifestyle Changes

Obesity is contributing to worse outcomes in people with COVID-19. Dr. Naomi Parrella, medical director of the Rush Center for Weight Loss and Bariatric Surgery, explains how managing your weight can lower your risk for severe COVID symptoms and help you prevent other chronic diseases.

Sacubitril and Valsartan Combination Treatment May Reduce Hypertensive Kidney Disease

Article title: Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension Authors: Iuliia Polina, Mark Domondon, Rebecca Fox, Anastasia V. Sudarikova, Miguel Troncoso, Valeriia Y. Vasileva, Yuliia Kashyrina, Monika Beck Gooz, Ryan S. Schibalski, Kristine Y.…

Clinical Trial to Investigate Whether Hypertension Drug Ameliorates COVID-19 Severity

UC San Diego scientists have launched a clinical trial to investigate whether a drug approved for treating high blood pressure might also reduce the severity of COVID-19 infections, lowering rates for intensive care unit admissions, the use of mechanical ventilators and all-cause mortality.

Mount Sinai Researchers Develop Novel Method to Identify Patterns Among Patients With Multiple Chronic Conditions

A study by researchers at Icahn School of Medicine at Mount Sinai proposes a novel method for identifying patterns in the frequency and cost of multiple chronic conditions (MCC).