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UrduHIV has an “early and substantial” impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection.
Tag: Heart Disease
Stalling Improvements in Cardiovascular Disease Rates Since 2010 Could Cost £54bn Between 2020 and 2029
New research published today suggests that the slowdown in improvements in cardiovascular diseases like heart disease and stroke seen in England and Wales since 2010 could cost £54billion in health and social care costs.
Vitamin D Supplements May Offset Bone Loss Caused by Diabetes Drug
Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug. Researchers will present their work this week at the American Physiological Society (APS) and American Society for Nephrology Control of Renal Function in Health and Disease conference in Charlottesville, Virginia.
Specific Environmental Exposures may Help Predict Increased Risk of Death from Cardiovascular Disease
A new study from the Icahn School of Medicine at Mount Sinai quantifies the cardiovascular risk posed by exposure to specific environmental factors, showing, for example, that air pollution heightens the risk of heart disease mortality by 17 percent.
Women’s heart attacks are often missed. This gene may help explain why.
Newly identified genes may help explain why women experience different heart disease symptoms than men do, which often leads to misdiagnosing serious problems.
Faculty Scientists and Clinicians Publish Findings of World’s First Successful Transplant of Genetically Modified Pig Heart into Human Patient
Six months ago, University of Maryland School of Medicine surgeon-scientists successfully implanted a genetically modified pig heart into a 57 year-old patient with terminal heart disease in a first-of-its-kind surgery.
Heart Failure Patients Unvaccinated Against COVID-19 Are Three Times More Likely to Die From It Than Boosted Heart Failure Patients
EMBARGOED UNTIL JUNE 9, 2022, 10AM EST (New York, NY – June 9, 2022) – Heart failure patients who are unvaccinated against SARS-CoV-2, the virus that causes COVID-19, are three times more likely to die if infected with the virus…
Researchers Establish a Profile of the COVID-19 Deceased Based on the Analysis of 140 Cases of Complete Autopsies
Men aged between 60 and 77 with Diffuse Alveolar Damage (DAD) –acute lung injury– in proliferative phase.
Blocking Endothelin Receptors May Help People with Obesity Burn Calories, Reduce Heart Disease Risk
Article title: Dual endothelin receptor antagonism increases resting energy expenditure in people with increased adiposity Authors: Cassandra C. Derella, Anson M. Blanks, Andy Nguyen, Jacob Looney, Matthew A. Tucker, Jinhee Jeong, Paula Rodriguez-Miguelez, Jeffrey Thomas, Matthew Lyon, David M. Pollock,…
Clarkston health fair offers free screenings, fun family activities for people with diabetes
Endocrine experts will provide free health services and fun family activities to the local refugee and immigrant community of DeKalb County during EndoCares® Atlanta, an in-person health education event being held on Saturday, June 11.
New Gene Identified in Arrhythmogenic Cardiomyopathy
Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells.
Ultrasound-Assisted Laser Technique Vaporizes Artery Plaque #ASA182
Atherosclerosis, a buildup of plaque, can lead to heart disease, artery disease, and chronic kidney disease and is traditionally treated by inserting and inflating a balloon to expand the artery. During the 182nd ASA Meeting, Rohit Singh, of the University of Kansas, will present a method that combines a low-power laser with ultrasound to remove arterial plaque safely and efficiently.
New research may explain unexpected effects of common painkillers
Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body.
Haywire T cells attack protein in “bad” cholesterol
Detecting these T cells may lead to diagnostics to better detect heart disease—and disease severity.
Late-Breaking Science Announced for TVT 2022
The Cardiovascular Research Foundation (CRF) announced that TVT: The Structural Heart Summit will feature 12 studies as Late-Breaking Clinical Science and Featured Clinical Research. An annual meeting covering cutting-edge research and techniques for structural heart interventions, TVT will take place June 8-10, 2022, at the Sheraton Grand Chicago Riverwalk in Chicago, Illinois.
From cavefish to humans: Evolution of metabolism in cavefish may provide insight into treatments for a host of diseases such as diabetes, heart disease, and stroke
New research examines how cavefish developed unique metabolic adaptations to survive in nutrient-scarce environments. The study created a genome-wide map of liver tissue for two independent colonies of cavefish along with river fish to understand how cavefish metabolism evolved and how this may be applicable for humans.
TVT 2022 Program Now Available
The program for TVT 2022: The Structural Heart Summit is now available online. An annual meeting from the Cardiovascular Research Foundation (CRF), TVT features cutting-edge research and techniques for structural heart interventions and will take place June 8-10, 2022 at the Sheraton Grand Chicago Riverwalk in Chicago, Illinois.
“One-size-fits-all” flawed for assessing cardiovascular disease risk among Asian Americans
In a large, retrospective study covering data from the last two decades, death rates for cardiovascular diseases in the U.S. varied among people from various Asian ethnicity subgroups, with death rate trends that stagnated in some subgroups and increased in others, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed journal of the American Heart Association.
Seattle health fair offers free screenings, wellness activities for people with diabetes
Endocrine experts will deliver free health services to underrepresented communities, including Latinx and Hispanic residents, during EndoCares® Seattle, an in-person health education event being held on May 14.
Media Registration for TCT 2022 Now Open
Media registration is now open for TCT 2022 (Transcatheter Cardiovascular Therapeutics), the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT will be held September 16-19, 2022, in Boston, Massachusetts at the Boston Convention and Exhibition Center.
Researchers ID Post-exercise Changes in MicroRNA as Potential Markers for Coronary Artery Disease
Article title: Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise Authors: Maria Dalen Taraldsen, Rune Wiseth, Vibeke Videm, Anja Bye, Erik Madssen From the authors: “This exploratory study demonstrated six miRs associated with coronary necrotic…
Mayo researchers use AI to detect weak heart pump via patients’ Apple Watch ECGs
Single-lead ECG tracings from an Apple Watch interpreted by an artificial intelligence (AI) algorithm developed at Mayo Clinic effectively identified patients with a weak heart pump.
Could exercise counteract cardiotoxic chemotherapy for women with breast cancer
When you’re a breast cancer survivor, the last thing you need is another health scare. So, it’s concerning to know that up to 48 per cent of breast cancer patients will go on to fight heart disease as a direct result of chemotherapy.
New study finds childhood abuse linked to higher risk for high cholesterol as an adult
A new study found risk factors for heart disease and stroke were higher among adults who said they experienced childhood abuse and varied by race and gender.
Stress during Pregnancy May Lead to Heart Disease, Accelerated Aging in Next Generation
Prenatal stress can cause damage in the aorta in offspring, which may contribute to the development of atherosclerosis and accelerate aging, according to a new study in mice. The article is published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.
People with diabetes and cognitive decline may be at higher risk for heart disease
People with type 2 diabetes who have cognitive impairment could be at greater risk for stroke, heart attack or death than other individuals with diabetes, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism.
Investigational Anti-Clotting Drug Reduces Bleeding Risk Among AF Patients
A new type of anti-clotting drug caused fewer bleeding incidents among patients with atrial fibrillation than the commonly prescribed apixaban, according to results from a head-to-head comparison of the two.
Few Patients Have Infected Heart Devices Removed Despite Lifesaving Benefits
Medicare patients whose implantable heart devices became infected were less likely to die from the complication if they had the hardware removed compared to patients who only received antibiotics, according to the largest study on the topic, led by the Duke Clinical Research Institute.
Investigational Drug for Heart Failure has Little Impact on Exercise Tolerance
Heart failure patients taking the investigational drug omecamtiv mecarbil, which has been previously shown to improve long-term outcomes, see little impact on their ability to exercise compared to a placebo, according to a study supported by the Duke Clinical Research Institute.
Cleveland Clinic-Led Trial Finds That Experimental ‘Gene Silencing’ Therapy Reduces Lipoprotein(a), an Important Risk Factor of Heart Disease, By Up To 98%
Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental “gene silencing” therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.
Findings from the “APOLLO Trial: Magnitude and Duration of Effects of a Short-interfering RNA Targeting Lipoprotein(a): A Placebo-controlled Double-blind Dose-ranging Trial” were presented today during a late-breaking science session at American College of Cardiology’s 71st Annual Scientific Session and simultaneously published online in the Journal of the American Medical Association.
Cleveland Clinic-Led Trial Shows Drug Effective in Nearly 80% of Patients with Hypertrophic Cardiomyopathy
Findings from a Cleveland Clinic-led clinical trial showed that the use of an experimental drug in severely symptomatic, hypertrophic cardiomyopathy patients significantly reduced the need for invasive procedures.
Exercise Improves Health Markers in Young Female Survivors of Childhood Trauma
New research shows a progressive exercise training program mitigates some physiological and psychological effects of adverse childhood experiences in otherwise healthy young women. The study will be presented at the American Physiological Society annual meeting at Experimental Biology 2022.
Virtual Population Model Predicts and Stops Kidney Damage in Black Americans
Researchers have successfully used a virtual population to replicate a clinical trial that examined kidney damage in Black Americans, according to a new study at the University of Mississippi Medical Center in Jackson.
Understanding the American Heart Association’s Latest Dietary Guidelines
A description of the American Heart Association’s new dietary guidelines.
Pathomechanisms in heart disease discovered
Titin is a “titanically large” protein – the largest in the human body – which enables elastic movements of our muscles, including the heart.
American Heart Association Honors Two Penn Medicine Scientists for Achievements in Research
Two Penn Medicine faculty members, Kiran Musunuru, MD, PhD, and Daniel Rader, MD, are being honored with prestigious awards from the American Heart Association (AHA) for their achievements in cardiovascular research. Both awards will be presented during the Presidential Session on Sunday, Nov. 14, at the association’s Scientific Sessions 2021.
Penn Study Illuminates the Biology of Common Heart Disorder
Dilated cardiomyopathy due to titin gene mutations involves both a shortage of good titin and a buildup of mutant, potentially “bad” titin
CRF Announces Free Online Access to TCT 2021
The Cardiovascular Research Foundation (CRF) is pleased to announce that the digital component of TCT 2021 will now be free for the entire interventional community. After careful consideration and achieving a critical level of support, CRF’s leadership has agreed to fully support this initiative. Complimentary online registration will include access to all content via livestream during the meeting and on-demand access for one year.
Low-dose Aspirin No Longer Recommended to Prevent Cardiovascular Disease
New draft recommendations from the U.S. Preventive Services Task Force recommend against taking aspirin to prevent heart attacks and strokes for most people. The Oct. 12, 2021 guidelines are based on new evidence showing that the risks of daily low-dose…
Researchers Look to Deleted Mitochondrial Protein to Treat Heart Disease
Article title: Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome Authors: Jessica N. Peoples, Nasab Ghazal, Duc M. Duong, Katherine R. Hardin, Janet R. Manning, Nicholas T. Seyfried, Victor Faundez, Jennifer Q. Kwong…
Meeting sleep recommendations could lead to smarter snacking
Missing out on the recommended seven or more hours of sleep per night could lead to more opportunities to make poorer snacking choices than those made by people who meet shut-eye guidelines, a new study suggests.
CRF Announces TCT 2021 Late-Breaking Trials and Science
The Cardiovascular Research Foundation (CRF) has announced 22 late-breaking trial and science presentations that will be reported at TCT 2021. TCT is the annual scientific symposium of CRF and the world’s premier educational meeting specializing in interventional cardiovascular medicine. It will take place November 4-6, 2021 in Orlando, Florida at the Orange County Convention Center and simultaneously broadcast live.
Memorial Hermann First in Texas to Use Newly-Approved Device to Treat Atrial Fibrillation in Patients at Risk of Stroke
Memorial Hermann in Houston, TX is the first institution in Texas to use a new device to treat AFib in patients at risk of stroke.
‘Leaky’ Heart Valves in Pregnant Women Need More Attention Than Once Thought, Study Suggests
An analysis of more than 20,000 individual medical records suggests that a form of heart valve disease thought to be relatively benign during pregnancy may put women at risk for serious bleeding, high blood pressure, organ damage and other complications during childbirth, according to research from Johns Hopkins Medicine.
Having MS Plus Depression May Be Tied to Increased Risk of Death
Depression is common in people with multiple sclerosis (MS), and a new study shows that people with both conditions may be more likely to die over the next decade than people with just one or neither condition. The study is published in the September 1, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found that people with MS and depression have an increased risk of developing vascular disease such as heart attack and stroke.
Diverse DNA signatures linked to heart disease
Risk for heart disease does not look the same on the genetic level for different population groups, report an international team of researchers this month in the journal JAMA Cardiology. The study, led by Texas Biomedical Research Institute (Texas Biomed) and Columbia University Mailman School of Public Health, begins to outline gene activity patterns that could serve as early warning indicators for cardiovascular disease.
Examining Correlation Between Occupational Noise, Heart Disease
Hearing conservation programs and policies aim to protect workers from noise-induced hearing loss, but it remains unclear whether stress reactions caused by noise exposure might also lead to other negative health outcomes. In The Journal of the Acoustical Society of America, researchers describe how data from the Canadian Health Measures Survey do not support an association between loud noise exposure and changes in biomarkers for cardiovascular disease or outcomes.
Muscle Protein That Makes Vertebrates More Fit Linked to Limited Lifespan
Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals. Their experiments working with mice and fruit flies, however, found that the gene for CaMKII also contributes to an evolutionary tradeoff: increased susceptibility to age-associated diseases, frailty and mortality.
Eating More Plant Foods May Lower Heart Disease Risk in Young Adults, Older Women
Eating more nutritious, plant-based foods is heart-healthy at any age, according to two research studies published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.
Most Comprehensive Review Yet of Keto Diets Finds Heart Risks, Cancer Risk, Dangers to Pregnant Women and Kidney Patients
In the most comprehensive analysis yet of ketogenic (keto) diets, a review in Frontiers in Nutrition finds keto diets place pregnant women and kidney disease patients at risk of adverse health effects.