news, journals and articles from all over the world.
Embargoed press materials are now available for the virtual Experimental Biology (EB) 2021 meeting, featuring cutting-edge multidisciplinary research from across the life sciences. EB 2021, to be held April 27–30, is the annual meeting of five scientific societies bringing together thousands of scientists and 25 guest societies in one interdisciplinary community.
Read moreReporters are invited to join a live Q&A discussion of exciting research announcements at the forefront of the life sciences during a virtual press conference for the Experimental Biology (EB) 2021 meeting. The press conference will be held online from 1–1:45 p.m. EDT on Monday, April 26, 2021 (RSVP by Friday, April 23).
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New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it — the list of pharmaceutical options to treat diabetes gets longer and longer.
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A new Viewpoint article argues that today’s health and equity challenges call for the U.S. to shift from “food insecurity” to “nutrition insecurity” in order to catalyze appropriate focus and policies on access not just to food but to healthy, nourishing food.
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During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.
Read moreFish oil supplements are a billion-dollar industry built on a foundation of purported, but not proven, health benefits. Now, new research from a team led by a University of Georgia scientist indicates that taking fish oil only provides health benefits if you have the right genetic makeup.
Read moreA new study has found that about 35% of Americans with a cancer history had an elevated risk of cardiovascular disease in the next decade, compared with about 23% of those who didn’t have cancer.
Read moreA new research paper funded in part by the National Heart, Lung and Blood Institute (NHLBI) shows a clear advantage of genetic testing in helping health care providers choose the appropriate anti-platelet drug. Testing helps determine if a patient carries genetic variants in CYP2C19 that cause loss of its function. These variants interfere with the body’s ability to metabolize and activate clopidogrel, an anti-platelet medication.
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A new UCLA study shows that while men and women who have high muscle mass are less likely to die from heart disease, it also appears that women who have higher levels of body fat — regardless of their muscle mass — have a greater degree of protection than women with less fat.
Read moreState-of-the-Art Facility and Multidisciplinary Team Approach Expands Care for Children with Complex Congenital Heart Defects
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Women who experience an accelerated accumulation of abdominal fat during menopause are at greater risk of heart disease, even if their weight stays steady, according to a University of Pittsburgh Graduate School of Public Health-led analysis published today in the journal Menopause.
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The heart cannot regenerate new tissue, because cardiomyocytes, or heart muscle cells, do not divide after birth. However, researchers have now developed a shape memory polymer to grow cardiomyocytes. Raising the material’s temperature turned the polymer’s flat surface into nanowrinkles, which promoted cardiomyocyte alignment. The research is part of the growing field of mechanobiology, which investigates how physical forces between cells and changes in their mechanical properties contribute to development, cell differentiation, physiology, and disease.
Read moreArticle title: Regular aerobic exercise counteracts endothelial vasomotor dysfunction associated with insufficient sleep Authors: Kelly A. Stockelman, Anthony R. Bain,
Read moreArticle title: Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of
Read moreArticle title: Habitual cannabis use is associated with altered cardiac mechanics and arterial stiffness, but not endothelial function in young
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The Association of Black Cardiologists, Inc. (ABC) and the Cardiovascular Research Foundation (CRF) is offering a complimentary online seminar, “Tackling Disparities in CV Care: A Closer Look at Hypertension and Heart Failure” on Friday February 26, 2021. The program is part of a joint initiative called A New Beat which advocates for women and minorities rising as leaders in cardiology. It aims to foster careers of female and minority cardiologists, who can be poised to improve access to quality care for underserved populations.
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Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention.
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William O’Neill, M.D., director of the Center for Structural Heart Disease at Henry Ford Health System, has donated $1 million to establish the Carol S. O’Neill Structural Heart Disease Research Fund at Henry Ford Health System in honor of his late wife, Carol, who passed away in 2019.
Read moreThe Heart Valve Collaboratory (HVC) announced today that the U.S. Food and Drug Administration (FDA)’s Center for Devices and Radiological Health (CDRH) will participate in this “collaborative community”. A medical “collaboratory” is a forum in which multidisciplinary private and public sector members work together on medical device challenges to achieve aligned outcomes, solve shared problems, and leverage collective opportunities, in the interest of improving patient care.
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By: Kelsey Klopfenstein | Published: February 3, 2021 | 1:14 pm | SHARE: Heart disease is the leading cause of death in the United States. Someone has a heart attack every 39 seconds, and cardiovascular disease claims more lives each year than all forms of cancer combined, according to the American Heart Association’s 2021 Heart Disease and Stroke Statistics Update.
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The Cardiovascular Research Foundation (CRF) will hold a free online seminar, The Big Three: High Blood Pressure, High Cholesterol, and Diabetes, at 12:00 PM ET on February 22, 2021 hosted by Drs. Nisha Jhalani and Sonia Tolani, cardiologists from NewYork-Presbyterian/Columbia University Irving Medical Center. The seminar is part of a series of “Mini Med Schools” conducted by the CRF Women’s Heart Health Initiative (WHHI), which empowers women with everyday tools they can use to defy heart disease.
Read moreA nationwide US study has found increasing death rates from heart disease in women under 65.
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Keck Medicine of USC experts offer insight into the connection between the heart and COVID-19 during American Heart Month
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Medical science has come a long way in efficiently diagnosing and effectively treating women with heart disease, but with upward of 500,000 women in the U.S. being treated for it every year, there is more work ahead, says one of the nation’s leading experts.
Read moreArticle title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling Authors: Vanessa P. Teixeira, Kiany
Read moreArticle title: SPARC production by bone marrow-derived cells contributes to myocardial fibrosis in pressure overload Authors: Hannah J. Riley, Ryan
Read moreIn a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition.
Read moreFebruary is American Heart Month and cardiologists from the Mount Sinai Health System are sharing tips on heart disease prevention to lower the risk of heart attack, stroke, and COVID-19.
Read moreAlthough cardiologists often decry coconut oil because of certain fats it contains, they overlook the growing evidence that other fatty constituents, especially medium-chain triglycerides, may alleviate some cases of mild cognitive impairment and Alzheimer’s disease
Read moreJefferson researchers find that the genetic underpinnings of a skin disorder at birth indicate future heart problems.
Read moreA small randomized study led by researchers at Tufts University suggests the omega-3 fatty acids EPA and DHA have different effects on chronic inflammation in older adults. Both omega-3s are found in fish oil.
Read moreAll educational programming from TCT Connect will be available to registrants for free through October 18, 2021. TCT is the annual scientific symposium of the Cardiovascular Research Foundation (CRF) and the world’s premier educational meeting specializing in interventional cardiovascular medicine.
Read morePeople who have coronary artery disease, stroke or peripheral artery disease often are prescribed a statin, a cholesterol-lowering drug that reduces the risk of heart attack or stroke.In a recent publication in JAMA Network Open, Mayo Clinic researchers identify trends in statin use across the U.S. among people with these diseases, as well as among those who already had a stroke or transient ischemic attack (TIA). Their data indicate that only about 60% of patients are getting the recommended therapy.
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Do people with COVID-19 run a risk of developing myocarditis? Cardiologist Dr. John Boehmer examines the latest research in this week’s Medical Minute.
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The Cardiovascular Research Foundation (CRF) has announced that the 2021 Chronic Total Occlusion (CTO) Summit will now take place as a virtual event called CTO Connect. It will take place online February 20-21, 2021.
The conference will feature live case transmissions performed by some of the world’s leading operators along with real-time analysis from world-class faculty members. Live and on-demand sessions will also highlight engaging case-based discussions, challenging cases, and the latest technical developments and refinements in CTO PCI.
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MedStar Washington Hospital Center became first in Washington, D.C. and central Maryland to adopt the HeartFlow® Analysis, a first-of-its-kind non-invasive technology to help physicians diagnosis heart disease and determine the next steps in treatment for each patient.
Read moreThailand’s Royal Family has named Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, a winner of the 29th annual Prince Mahidol Award in the field of Medicine.
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DALLAS – Nov. 9, 2020 – Reducing the level of body fat and waist size are linked to a lower risk of heart failure in patients with type 2 diabetes, a study led by UT Southwestern researchers indicates. The findings, reported today in Circulation, suggest that all weight loss isn’t equal when it comes to mitigating the risk of heart disease.
Read moreThe OPTIMIZE randomized trial comparing a novel, low-profile drug-eluting stent (DES) facilitating transradial access (TR) and direct stenting (DS) to existing DES did not establish non-inferiority of the new stent based on the prespecified study statistical analysis plan, likely due to the definition of periprocedural target vessel myocardial infarction (TVMI) coupled with a large proportion of high-sensitive cardiac troponin assays used in the trial.
Read moreFor patients undergoing percutaneous coronary intervention (PCI) that also require oral anticoagulation, treatment with a nanotechnology polymer-coated stent plus 14-day dual anti-platelet therapy (DAPT) did not reduce bleeding or establish non-inferior outcomes for thrombotic events compared with a drug-eluting stent (DES) and standard three or six-month DAPT therapy.
Read moreA new observational study of deferred lesions following combined fractional flow reserve (FFR) and coronary flow reserve (CFR) assessments found that untreated vessels with abnormal FFR but intact CFR do not have non-inferior outcomes compared to those with an FFR greater than 0.8 and a CFR greater than or equal to two when treated medically.
Read moreResults from the randomized controlled TARGET FFR trial show that while a physiology-guided percutaneous coronary intervention (PCI) optimization strategy did not achieve a significant increase in the proportion of patients with final FFR ≥0.90, it reduced the proportion of patients with a residual FFR ≤0.80 following PCI.
Read moreIn the FORECAST randomized clinical trial, the use of fractional flow reserve management derived from computed tomography (FFRCT) did not significantly reduce costs but did reduce the use of invasive coronary angiography (ICA).
Read moreThe MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance.
Read moreThe REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint.
Read moreIn a randomized clinical trial, SCOPE II, a new self-expanding bioprosthetic valve used in transcatheter aortic valve replacement (TAVR) failed to demonstrate non-inferiority compared to an existing self-expanding valve.
Read moreA new review suggests “heat-not-burn” tobacco devices may threaten cardiovascular health. The review is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology.
Read moreAn individual patient data pooled analysis comparing the use of bivalirudin versus heparin in heart attack patients undergoing percutaneous coronary intervention (PCI) found that bivalirudin use was associated with similar overall rates of 30-day mortality across all heart attack patients, but lower rates of serious bleeding events. Moreover, mortality was reduced in patients with ST-segment elevation myocardial infarction (STEMI) who were treated with a post-PCI bivalirudin infusion.
Read moreData from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.
ew data from the PROSPECT II study shows that NIRS-IVUS intracoronary imaging can help identify angiographically non-obstructive lesions with high-risk characteristics for future adverse cardiac outcomes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.
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