A new study from Washington University School of Medicine in St. Louis provides evidence that COVID-19 patients’ heart damage is caused by the virus invading and replicating inside heart muscle cells, leading to cell death and interfering with heart muscle contraction. The researchers used stem cells to engineer heart tissue that models the human infection and could help in studying the disease and developing possible therapies.
Article title: SPARC production by bone marrow-derived cells contributes to myocardial fibrosis in pressure overload Authors: Hannah J. Riley, Ryan R. Kelly, An O. Van Laer, Lily S. Neff, Shaoni Dasgupta, Catalin F. Baicu, Lindsay T. McDonald, Amanda C. LaRue,…
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.
Research may lead to identifying novel therapies for cardiac patients
The Smidt Heart Institute at Cedars-Sinai has established a specialized cardiac clinic to care for COVID-19 survivors who may be subject to long-term heart damage. Experts available for interviews in English and Spanish; HD video is available upon request.
International study may guide therapeutic strategies in patients with and without underlying heart conditions
Study findings may help doctors better triage coronavirus patients admitted to the hospital
A new clinical trial conducted at The Ohio State University Wexner Medical Center found a cost-effective generic medication works just as well as a more expensive drug in preserving cardiovascular function in boys with Duchenne muscular dystrophy (DMD).
Zebrafish and mammals share key cellular features; researchers have identified how the former repair their damaged hearts and now wonder if humans might someday be able to do so, too Research into the hearts of zebrafish, a pet shop staple…