Corticosteroid injections are a common treatment option for pain and inflammation in patients with osteoarthritis of the hip. But a new study adds to concerns that hip steroid injections may lead to increased rates of a serious complication called rapidly destructive hip disease (RDHD), according to a paper in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
A textile-based implant containing cartilage derived from stem cells reduced pain and restored hip joint function to baseline levels in a study of dogs with symptoms of moderate osteoarthritis.
Researchers at Michigan Medicine are creating a hybrid sleep-exercise intervention to mitigate osteoarthritis-related pain.
After a team of researchers showed that a certain enzyme’s presence in cartilage increased significantly in people with osteoarthritis, they targeted it with specially-loaded nanoparticles that stopped the disease’s progression in its tracks.
In a study released Feb. 22 in JAMA Internal Medicine researchers found that six 20-minute telephone calls over eight weeks coaching participants on how to get better sleep improved their sleep, pain, and daytime function. The improvements in sleep and daytime function persisted 12 months after treatment. One of the lead investigators who has been researching age and sleeping for 40 years offers great tips on getting better sleep. Just because you are aging, does NOT mean your sleep needs to get worse.
The 2021 Kappa Delta Young Investigator Award was presented to Lin Han, PhD, for research on the structure and function of cartilage extracellular matrix (ECM) and its impact on tissue regeneration and disease evolution in osteoarthritis (OA).
In a new study, scientists have discovered the cellular pathway that leads to osteoarthritis and have identified a commonly used anti-depressant — paroxetine — that inhibits this pathway.
Antidepressants are commonly used worldwide to treat pain, however new research from the University of Sydney shows they offer little to no help for people suffering chronic back pain and osteoarthritis and may even cause harm.
In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain
The cumulative incidence of hip dislocation following total hip replacement is about 50 percent higher than suggested by simple analysis of hospital data, reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that use of warfarin, a vitamin K drug widely prescribed to prevent blood clots, is associated with a significantly greater risk of knee and hip replacements in patients with osteoarthritis.
New research shows that corticosteroid injections for knee OA treatment do not hasten a patient’s progression to a total knee replacement when compared with hyaluronic acid injections. Details of this study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.
University of South Australia researchers are a step closer to finding a new biomarker for osteoarthritis, a painful condition which affects more than 300 million people worldwide.
One in five Canadian adults is currently living with arthritis, a disease causing inflammation of the joints, which can result in chronic, debilitating pain, reduced mobility and premature disability. Arthritis is the leading cause of disability globally. To address this growing crisis, the Schroeder Arthritis Institute, launched with a $25 million donation by philanthropists Walter and Maria Schroeder, will help UHN’s innovative arthritis program become a world-class hub for innovation in research, education and patient care.
Researchers have created a machine-learning algorithm that can pick up on subtle signs of osteoarthritis – too abstract to register in the eye of a trained radiologist – on an MRI scan taken years before symptom onset.
Injections of a natural “energy” molecule prompted regrowth of almost half of the cartilage lost with aging in knees, a new study in rodents shows.
Cappuccino, latte or short black, coffee is one of the most commonly consumed drinks in the world. But whether it’s good or bad for your health can be clarified by genetics, as a world-first study from the University of South Australia’s Australian Centre for Precision Health shows that excess coffee consumption can cause poor health.
Deva Chan, an assistant professor of biomedical engineering at Rensselaer Polytechnic Institute, is leading a team that will study the role that biomechanics plays in the production and function of hyaluronan in an effort to learn more about the factors that affect joint health and osteoarthritis. This research is being supported by a National Science Foundation Faculty Early Career Development (CAREER) Program Award.
Not running or jogging because you think it worsens or increases your risk for osteoarthritis?
Osteoarthritis affects 240 million people worldwide and is one of the most common causes of disability in both humans and animals. Currently, no therapeutics exist to prevent this disease, but recent multidisciplinary research at Cornell reveals that the application of a proprietary peptide known as SS-31 may protect cartilage from the injury that leads to arthritis.
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer’s and Parkinson’s diseases and other neurological disorders. The technology, which features a unique graphene and gold-based platform and high-tech imaging, monitors the fate of stem cells by detecting genetic material (RNA) involved in turning such cells into brain cells (neurons), according to a study in the journal Nano Letters.
Osteoarthritis can produce joint pain and stiffness sufficient to limit and even prohibit the performance of everyday tasks. It becomes more common with age, once it starts it typically gets worse and there’s no known cure. But there are therapies that can relieve pain and maintain joint function.