Rare Human Gene Variant in ADHD, Autism Exposes Fundamental Sex Differences

Key differences in male and female mice brains provide new insights into how sex determines the mechanisms by which distinct synapses monitor and regulate dopamine signaling. The impact of sex differences is particularly pronounced when the mice express a human genetic variant found in boys with either ADHD or autism. Behavioral generalizations across the sexes may limit diagnosis of mental illness, especially if one sex translates alterations into outward signs such as hyperactivity and aggression vs. more internal manifestations such as learning, memory and mood, even when the same molecular pathology is at work.

Summer Institute focused on life after high school for kids with autism, ADHD, more

The UC Davis MIND Institute’s annual Summer Institute on Neurodevelopmental Disabilities is focused on strategies to support individuals with ADHD, Down syndrome, autism and more as they prepare for life after high school. The free, virtual event will take place Aug. 3 from 9:00 a.m. – 1:15 p.m. and is open to all.

‘Eye-catching’ smartphone app could make it easy to screen for neurological disease at home

UC San Diego researchers developed a smartphone app that could allow people to screen for Alzheimer’s disease, ADHD and other neurological diseases and disorders—by recording closeups of their eye. The app uses a smartphone’s built-in near-infrared camera and selfie camera to track how a person’s pupil changes in size. These pupil measurements could be used to assess a person’s cognitive condition.

Does cannabis affect brain development in young people with ADHD? Too soon to tell, reports Harvard Review of Psychiatry

At least so far, the currently limited research base does not establish that cannabis has additional adverse effects on brain development or functioning in adolescents or young adults with attention-deficit/hyperactivity disorder (ADHD), concludes a review in the July/August issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.

ADHD Medications Associated with Reduced Risk of Suicidality in Children with Significant Behavioral Symptoms

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The findings, published today in JAMA Network Open, address a significant knowledge gap in childhood suicide risk and could inform suicide prevention strategies at a time when suicide among children is on the rise.

Study finds antibiotics before age 2 associated with childhood health issues

In a retrospective case study, Mayo Clinic researchers have found that antibiotics administered to children younger than 2 are associated with several ongoing illnesses or conditions, ranging from allergies to obesity. The findings appear in Mayo Clinic Proceedings.

Antibiotic Exposure in Children Under Age 2 Associated with Chronic Conditions

Children under age 2 who take antibiotics are at greater risk for childhood-onset asthma, respiratory allergies, eczema, celiac disease, obesity and attention deficit hyperactivity disorder, according to a paper written jointly by Mayo Clinic and Rutgers researchers. While previous studies have looked at the association of antibiotics with single diseases, this is the first to look at the association across many diseases.

Self-regulation for kids: at home, at school and with autism

As every teacher will assert, self-regulation is the key to optimal learning; it helps kids tune in, stay focussed and be ready to learn. But what if your child isn’t wired this way? For many children, self-regulation is hard to master, but for kids on the autism spectrum, it can seem insurmountable, singling them out and creating barriers to their learning.

Teens with a History of ADHD Need Stronger Monitoring of Health Risks

Adolescents with a history of attention-deficit/hyperactivity disorder (ADHD) are at an increased risk for a multitude of adverse outcomes, including sexually-transmitted infections (STIs), mental health conditions, and car accidents. Researchers from Children’s Hospital of Philadelphia (CHOP) wanted to better understand how primary care doctors addressed these risks with patients as they transitioned from childhood to young adulthood. They found that although doctors generally discuss depression, substance abuse, and suicide risk with patients who have a history of ADHD, they rarely discuss safe driving with them and most of the time they do not monitor patients for risky sexual behavior.

Young mums more likely to have kids with ADHD

Young mothers have a greater chance of having a child with attention deficit hyperactivity disorder (ADHD) according to new research from the University of South Australia. Exploring the genetic relationship between female reproductive traits and key psychiatric disorders, it found that the genetic risk of ADHD in children was strongly associated with early maternal age at first birth, particular for women younger than 20.