Targeting Molecular Pathway that Causes Pulmonary Arterial Hypertension

UC San Diego researchers describe the underlying signaling pathway that results in pulmonary arterial hypertension and a novel monoclonal antibody therapy that blocks the abnormal blood vessel formation characterizing the disease.

White Matter Changes in Brain Found in Frontotemporal Dementia

Areas of brain damage called white matter hyperintensities are commonly linked to vascular health problems. They have also been linked to Alzheimer’s disease. Now a new study has shown that white matter hyperintensities are also found in frontotemporal dementia. The study is published in the February 17, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Frontotemporal dementia, which often affects people under the age of 65, mainly results in changes in personality, behavior and problems with language rather than memory.

Earlier detection of women’s vascular health issues can affect heart disease risk, Mayo Clinic study advises

Men and women differ in the way their vascular systems age and the rate at which atherosclerosis ― the hardening of artery walls or buildup of arterial blockage ― progresses over time. These sex- and age-related differences have a direct bearing on a woman’s risk factors for cardiovascular disease.