A randomized controlled trial of 400 adults aged 70 years or older with chronic kidney disease (CKD) found that use of the decision-making aid DART (Decision-Aid for Renal Therapy) improved decision quality and clarified treatment preferences among older adults with advanced CKD for 6 months after the DART intervention. The findings are published in Annals of Internal Medicine.
Tag: Chronic Kidney Disease
Dapagliflozin reduces risk for hospitalization in patients with CKD with or without diabetes
Dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, reduced the risk for hospitalization for any cause in patients with chronic kidney disease (CKD) with and without type 2 diabetes.
New onset chronic kidney disease in people with diabetes highest among ethnic, racial minorities
New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates were higher by approximately 60%, 40%, 33%, and 25% in the Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations, respectively, compared to white persons with diabetes.
Inhaling Silica Particles May Cause Kidney Disease
New research in rats demonstrates that inhaling amorphous silica particles—of the size released from burning sugarcane—could damage the kidneys. The study, chosen as an APSselect for August, is published ahead of print in the American Journal of Physiology-Renal Physiology.
Tip Sheet: Studies on COVID-19, TV and Toddler Diet Among Johns Hopkins Research to Be Featured at National Pediatrics Meeting
What: Pediatric Academic Societies (PAS) 2022 Meeting
When: April 21 to 25
Where: Colorado Convention Center (700 14th St., Denver, CO 80202)
Chronic Kidney Disease is Curable if Detected Early – Chula’s User-friendly CKD Screening Strips with Results in 15 minutes!
A Chula research team has developed a screening strip kit to detect the early stage of chronic kidney disease (CKD) that’s easy to use, yields quick results, increasing the chance of being cured for patients, and helping to cut over 10 billion baht of the ever-increasing annual healthcare costs for CKD patients. The CKD screening strip kits are expected to be released early next year.
The enzyme that could help 700 million people worldwide
University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.
Surprise Discovery Shows Chronic Heart Dysfunction Protects against Acute Kidney Injury
Article title: Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction Authors: Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinwechi Nwosisi, Ming-Zhi Zhang, Raymond C. Harris From the authors:…

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.
Blood-flow Restriction Training Delay the Progression of Chronic Kidney Disease
Chronic kidney disease (CKD) is recognized as a public health problem, affecting more than 15% of the population. Although CKD can drastically impair health, it is rarely diagnosed early due to its silent revelation. Identifying and proposing treatments to attenuate…
New Blood Pressure-Lowering Guidelines Could Benefit 25 Million Americans with Chronic Kidney Disease
A recommendation for more intensive blood pressure management from an influential global nonprofit that publishes clinical practice guidelines in kidney disease could, if followed, benefit nearly 25 million Americans.
Blocking Calcium Channel May Prevent Calcification in Kidney Disease
Inhibiting the Kv1.3 channel, a potassium channel expressed in tissues around the body, including vascular smooth muscle cells, may help prevent uremia-induced calcification in people with chronic kidney disease. The study is published ahead of print in the journal Function.…
Kidney Disease Affects Men’s Blood Vessel Health More
Men who suffer from chronic kidney disease (CKD) have greater rates of reduced blood vessel function compared to women with the same disorder.
Sugary Soda Consumption Linked to Reduced Kidney Blood Flow
Regular consumption of sugary soda sweetened with high-fructose corn syrup (HFCS) reduces kidney blood flow, which could be linked to a greater risk of developing chronic kidney disease (CKD), according to a recently published paper in the American Journal of Physiology-Renal Physiology.
Sugary Sodas Linked to Increased Risk of Chronic Kidney Disease
Article title: High-fructose corn syrup-sweetened soft drink consumption increases vascular resistance in the kidneys at rest and during sympathetic activation Authors: Christopher L. Chapman, Tigran Grigoryan, Nicole T. Vargas, Emma L. Reed, Paul J. Kueck, Leonard D. Pietrafesa, Adam C. Bloomfield,…

Link between chronic kidney disease and heart failure is identified in patients
People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Now, for the first time in humans, researchers have identified a pathological change that appears to link kidney disease to progressive heart disease.
Nicotine Boosts Production of Inflammation-causing Hormones, Worsens Kidney Disease
Article title: COX-2 derived prostaglandins as mediators of the deleterious effects of nicotine in chronic kidney disease Authors: Sunil Rangarajan, Gabriel Rezonzew, Phillip Chumley, Huma Fatima, Mikhail Golovko, Wenguang Feng, Ping Hua, Edgar A. Jaimes From the authors: “In these studies,…
Chronic kidney disease patients at increased risk of adverse cardiovascular outcomes, Mayo Clinic study finds
Chronic kidney disease, which afflicts an estimated 6.4% of U.S. adults 45 and older, is associated with an increased risk of heart attack and other adverse cardiovascular outcomes, according to new research from Mayo Clinic.

Common Clinical Estimates of Kidney Function May Not Accurately Assess Indian Patients
Pilot study finds that considering body composition rather than weight could improve patient management Charlottesville, Va. (June 25, 2019)—A common metric for monitoring kidney health may not accurately represent the kidney function of Indian patients. However, tweaks to an older…