Either ACEi or ARB therapy protect against kidney failure in those with advanced CKD

A systematic review and retrospective individual participant-level meta-analysis of 18 trials comprised of more than 1,700 participants found that initiating treatment with an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin-receptor blocker (ARB) protects against kidney failure in patients with advanced chronic kidney disease (CKD).

Chulalongkorn Unveils “Microalbuminuria Rapid Test”: Easy, Accurate, Ready for Commercial Use

Ms. Supamas Isarabhakdi, Minister of Higher Education, Science, Research and Innovation, attended the launching of the innovative Microalbuminuria Rapid Test developed by a team of experts and researchers from the Faculty of Medicine, Chulalongkorn University. The test, which is convenient and easy to use and offers high accuracy, allows users to self-screen for kidney damage, giving it commercial potential in order to enhance Thailand’s healthcare system. It is expected for distribution in mid-2024.

Men with Chronic Kidney Disease Have Higher Resting Activity in ‘Fight-or-Flight’ System than Women

Article title: Sex differences in sympathetic activity and vascular stiffness in adults with chronic kidney disease (CKD) Authors: Matias G. Zanuzzi, Jinhee Jeong, Dana R. DaCosta, Jeanie Park From the authors: “We show for the first time that males with…

UT Southwestern study shows glucagon is key for kidney health

Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health. When UT Southwestern Medical Center researchers removed receptors for this hormone from mouse kidneys, the animals developed symptoms akin to chronic kidney disease (CKD).

Measuring eGFR based on cystatin C levels may be a more accurate assessment of kidney function in older adults

A study of more than 82,000 older adults receiving outpatient measurements of estimated glomerular filtration rate (eGFR) found that measuring eGFR based on creatinine and cystatin C levels (eGFRcr-cys) was more strongly associated with adverse outcomes than measuring eGFR with only creatinine levels (eGFRcr).

Cardiac Arrest: Hispanics, Latinos With Kidney Disease at High Risk

Hispanics and Latinos with chronic kidney disease are at significant risk for suffering from sudden cardiac arrest, according to a new study from the Smidt Heart Institute at Cedars-Sinai.

Acute kidney injury not associated with worsening kidney function in persons with CKD

A study of hospitalized persons with chronic kidney disease (CKD) fournd that acute kidney injury (AKI) did not predict worsening of kidney function trajectory once difference in pre-hospitalization characteristically were fully accounted for. Instead, the authors suggest that much of determinants of faster kidney disease decline observed after AKI may already be present before AKI. The findings are published in Annals of Internal Medicine.

AACC and National Kidney Foundation Release Guidance to Combat Racial and Gender Inequalities in Chronic Kidney Disease Care

Today, AACC—in collaboration with the National Kidney Foundation (NKF)—released guidance to reduce racial and gender disparities in the care of patients with chronic kidney disease (CKD). The document gives members of the healthcare team actionable, evidence-based tools to improve equity in kidney health, including recommendations for using an updated algorithm that does not disproportionately affect any one group of individuals.

Study Finds Certain Substances in Urine, Blood Can Predict Kidney Disease Progression

In a new study looking at the long-term effects of hospitalized patients who have acute kidney injury (AKI), a sudden but temporary loss of kidney function, Johns Hopkins Medicine researchers found that higher levels of certain biomarkers in urine and blood can predict a patient’s risk of developing chronic kidney disease (CKD).

Three Kidney Transplants, Weight Gain and a Journey Back to Wellness

Rowena Roque, 46, was having a problem that many people can relate to: doing everything in her power to lose weight and get healthy but never succeeding.

Large Study Identifies Risk Factors in Children with Chronic Kidney Disease

In a new study led by Children’s Hospital of Philadelphia (CHOP) and Nemours Children’s Health, researchers have overcome the obstacle of scale by analyzing electronic health record data from PEDSnet, a national multicenter pediatric network, to identify a large cohort of children with CKD, evaluate CKD progression, and examine clinical risk factors for kidney function decline. The findings were published in the Clinical Journal of the American Society of Nephrology.

Digital decision aid may help older adults with CKD make better quality treatment decisions

A randomized controlled trial of 400 adults aged 70 years or older with chronic kidney disease (CKD) found that use of the decision-making aid DART (Decision-Aid for Renal Therapy) improved decision quality and clarified treatment preferences among older adults with advanced CKD for 6 months after the DART intervention. The findings are published in Annals of Internal Medicine.

New onset chronic kidney disease in people with diabetes highest among ethnic, racial minorities

New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates were higher by approximately 60%, 40%, 33%, and 25% in the Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations, respectively, compared to white persons with diabetes.

Chronic Kidney Disease is Curable if Detected Early – Chula’s User-friendly CKD Screening Strips with Results in 15 minutes!

A Chula research team has developed a screening strip kit to detect the early stage of chronic kidney disease (CKD) that’s easy to use, yields quick results, increasing the chance of being cured for patients, and helping to cut over 10 billion baht of the ever-increasing annual healthcare costs for CKD patients. The CKD screening strip kits are expected to be released early next year.

Surprise Discovery Shows Chronic Heart Dysfunction Protects against Acute Kidney Injury

Article title: Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction Authors: Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinwechi Nwosisi, Ming-Zhi Zhang, Raymond C. Harris From the authors:…

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.

Blood-flow Restriction Training Delay the Progression of Chronic Kidney Disease

Chronic kidney disease (CKD) is recognized as a public health problem, affecting more than 15% of the population. Although CKD can drastically impair health, it is rarely diagnosed early due to its silent revelation. Identifying and proposing treatments to attenuate…

Chronic kidney disease patients at increased risk of adverse cardiovascular outcomes, Mayo Clinic study finds

Chronic kidney disease, which afflicts an estimated 6.4% of U.S. adults 45 and older, is associated with an increased risk of heart attack and other adverse cardiovascular outcomes, according to new research from Mayo Clinic.

American Physiological Society (APS)

Common Clinical Estimates of Kidney Function May Not Accurately Assess Indian Patients

Pilot study finds that considering body composition rather than weight could improve patient management Charlottesville, Va. (June 25, 2019)—A common metric for monitoring kidney health may not accurately represent the kidney function of Indian patients. However, tweaks to an older…