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UrduScientists at the UC Davis School of Medicine may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.
Tag: gut microbes
UIC awarded $3M to study link between gut microbiome, pain in kidney transplant patients
Funded by NIH, the five-year study builds off a pilot study that pointed to an association between changes in the gut microbiome and pain that interferes with a person’s daily activities, a symptom that nearly half of kidney transplant patients experience.
Beneficial bacteria sense gut mucus to stay in line
The findings point to possible mechanisms behind intestinal conditions like Crohn’s disease and ulcerative colitis, and also suggest avenues to develop more effective probiotics.
The heart benefits of walnuts likely come from the gut
A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut.
How Gut Microbes Help Mend Damaged Muscles
Now, in a surprising new discovery, Harvard Medical School researchers have found that a class of regulatory T cells (Tregs) made in the gut play a role in repairing injured muscles and mending damaged livers.
In an even more unexpected twist, the researchers found that gut microbes fuel the production of Tregs, which act as immune healers that go on patrol around the body and respond to distress signals from distant sites of injury.
Research of a Wild Primate Shows Maternal Effects Key to Gut Microbial Development
A study of wild geladas provides the first evidence of clear and significant maternal effects on the gut microbiome both before and after weaning in a wild mammal. This study suggests the impact of mothers on the offspring gut microbiome community extends far beyond when the infant has stopped nursing.
Gut microbes may lead to therapies for mental illness, UTSW researcher reports
The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years. Now evidence is mounting that this collection of microorganisms in the human gut can also impact a person’s neurological and emotional health, according to a recent perspective article in Science by a UT Southwestern researcher.
Bacterial Bullseye
The study findings suggest possibilities for developing new drugs that replicate or build on A. muciniphila’s immuno-modulatory activity.
The work provides a model for using traditional techniques to pinpoint how other members of the gut microbiome act on the body.
“Intestinal Microflora” as Health Indicator, A National-level Research Project by Chula Doctors in Response to Problems of an Aging Society
Chula’s Faculty of Medicine pioneers Thailand’s first research work that studies “Intestinal Microflora Microbiome of the Aged” which gathers basic information at the national level to unlock the relationship between the wellness of the aged and intestinal microflora that can predict risks of diseases and health and the population’s wellbeing.
Gut Check
At a glance:
Researchers identify links between genetic makeup of bacteria in human gut and several human diseases
Clusters of bacterial genes present in conditions including cardiovascular illness, inflammatory bowel disease, liver cirrhosis, and cancer
Work brings scientist closer to developing tests that could predict disease risk or identify disease presence based on a sampling of the genetic makeup of a person’s microbiome
How pregnancy turns the stress response on its head
Researchers found two simultaneous conditions in pregnancy’s response to stress that made them realize just how complex the cross-talk between mom and baby is during gestation: Immune cells in the placenta and uterus were not activated, but significant inflammation was detected in the fetal brain.
Science Snapshots From Berkeley Lab
These news briefs cover topics including gut microbes, tsetse flies in 3D, an energy use framework for heating and cooling, and new gravitational lensing candidates.
What Can the Gut Microbiome Tell Us About Health?
ILSI North America hosts Dr. Jaeyun Sung of the Mayo Clinic to discuss with participants the development of a gut microbiome-based health index.
Next-Generation Risk Assessment, Antimicrobials, and More Featured in July 2020 Toxicological Sciences
Published in this month’s edition of Toxicological Sciences are articles on biotransformation, toxicokinetics, and pharmacokinetics; developmental and reproductive toxicology; nanotoxicology; and more.
Scientists Explore Links Between Genetics, Gut Microbiome and Memory
Scientists have traced the molecular connections between genetics, the gut microbiome and memory in a mouse model bred to resemble the diversity of the human population. Researchers from two U.S. Department of Energy national laboratories identified lactate, a molecule produced by all species of one gut microbe, as a key memory-boosting molecular messenger.
A MOTHER’S BUGS
-Newborn mice derive protective antibodies from their mothers’ microbiota
-Antibodies derived from mothers’ microbiota ward off both localized and widespread systemic infections by the bacterium E. coli
-Study points to the role of maternal microbes in offspring protection and neonatal immunity
-Findings can inform development of microbe-based therapies against infectious diarrhea in infants
Gut microbes alter characteristics of norovirus infection
The highly contagious norovirus causes diarrhea and vomiting and is notorious for spreading rapidly through densely populated spaces, such as cruise ships, nursing homes, schools and day care centers. There are no treatments for this intestinal virus. A new study led by scientists at Washington University School of Medicine in St. Louis has shown that gut microbes can tamp down or boost the severity of norovirus infection based on where along the intestine the virus takes hold.