news, journals and articles from all over the world.
A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension.
A rapidly growing body of evidence shows the importance and effectiveness of cognitive rehabilitation for individuals with traumatic brain injury (TBI). A major update of the groundbreaking INCOG guidelines for cognitive rehabilitation following TBI is presented in the January/February special issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of America, JHTR is published in the Lippincott portfolio by Wolters Kluwer.
Researchers affiliated with the Council of State Neurological Societies investigated the impact of the COVID-19 pandemic on the treatment of traumatic brain injuries (TBIs) by evaluating data from the Michigan Trauma Quality Improvement Program (MTQIP).
Researchers from the Brain Injury Research Center at the Icahn School of Medicine at Mount Sinai, in partnership with the Pennsylvania Department of Corrections (PADOC) and the Brain Injury Assocation of Pennsylvania (BIAPA), have launched a rigorous research study to reduce recidivism, or re-offending, among people with brain injury who are leaving incarceration.
Scientists at the Icahn School of Medicine at Mount Sinai saw for the first time hallmarks of concussions and other head trauma in the brains of deceased headbutting animals—muskoxen and bighorn sheep. The results published in the journal Acta Neuropathologica may contradict the commonly-held belief that ramming animals do not suffer brain injuries and support the notion that studies on animals with brains evolutionarily similar to those of humans may help researchers understand and reduce traumatic brain injuries.
Approximately 1 in 50 people who suffer a traumatic brain injury (TBI) will develop post-traumatic epilepsy (PTE)—with the risk of PTE significantly higher in people with severe TBI. PTE is characterized by recurring seizures that begin a week or more after the brain injury, and there is currently no way to identify those at risk for developing PTE or to prevent its onset.
New research in mice raises the prospects for development of post-concussion therapies that could ward off cognitive decline and depression, two common conditions among people who have experienced a moderate traumatic brain injury.
The M.O.M. project, which will have four units in Ohio, Florida, South Carolina and Texas, will engage veterans with traumatic brain injury, their caregivers and other stakeholders to bolster patient-centered outcomes research and comparative effectiveness research in order to identify treatment options for traumatic brain injury that are effective, acceptable, and meaningful to the veteran population.
Adults with a history of traumatic brain injury (TBI), even years previously, are at increased risk of use and misuse of prescription opioid medications, reports a study in the September/October special issue of the Journal of Head Trauma Rehabilitation (JHTR).
Despite significant advances in treatment, sports-related concussion continues to plague athletes. Part of the reason for this is that the biological basis of concussion is poorly understood. Genetics play a key role in the biology underlying concussion. In this study,…
Two papers by researchers at Vanderbilt University Medical Center that extend our understanding of the Baylor GSWH scoring system and its application, externally validating it in a different group of patients presenting during a more recent time period in which better acute management techniques are available.
New research uses a unique survey tool to understand how caring for a person with TBI impacts the caregiver’s mental health and well-being.
Studies using repetitive transcranial magnetic stimulation (rTMS), a noninvasive technique, to help veterans and active-duty service members living with depression, post-traumatic stress disorder (PTSD), and other lasting consequences of concussion have shown promise. However, there’s an urgent need for studies designed to address the unique patterns of post-concussion symptoms seen in military populations, concludes a review in the November/December issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of America, JHTR is published in the Lippincott portfolio by Wolters Kluwer.
in a study with potential impacts on a variety of neurological diseases, Virginia Tech researchers have provided the first experimental evidence from a living organism to show that an abundant, star-shaped brain cell known as an astrocyte is essential for blood-brain barrier health.
Even mild concussions cause severe and long-lasting impairments in the brain’s ability to clean itself, and this may seed it for Alzheimer’s, dementia and other neurodegenerative problems.
As part of nationwide study to improve trauma care for severe brain injuries, researchers at UChicago Medicine are working to engage South Side residents and ensure representation among underrepresented communities.
Researchers at UC San Diego Health have joined a national research study called Hyperbaric Oxygen Brain Injury Treatment (HOBIT) to assess whether therapy involving 100 percent oxygen under pressure might also benefit patients with severe brain injuries.
How one professor’s quick thinking allowed music therapy to play on for clients at home
Researchers are studying how the collapse of microbubbles within the skull can damage brain cells. Their research could lead to the design of better helmets.
Article title: Increased myoinositol in the anterior cingulate cortex of veterans with a history of traumatic brain injury: a proton magnetic resonance spectroscopy study Authors: Chandni Sheth, Andrew P. Prescot, Margaret Legarreta, Perry F. Renshaw, Erin McGlade, Deborah Yurgelun-Todd From the…
Article title: Altered corticomotor latencies but normal motor neuroplasticity in concussed athletes Authors: William Stokes, Jake Choynowki, Maria St. Pierre, Manuel Alejandro Anaya, Matthew A. Statton, Pablo A. Celnik, Gabriela Cantarero From the authors: “We found that the number of concussions an…
A team of researchers at the University of Arizona has found that low-intensity ultrasound waves directed at a particular region of the brain’s prefrontal cortex in healthy subjects can elevate mood, and decrease connectivity in a brain network that has been shown to be hyperactive in psychiatric disorders. The method uses transcranial focused ultrasound (‘tFUS’), a painless, non-invasive technique to modulate brain function comparable to transcranial magnetic stimulation (‘TMS’), and transcranial direct current stimulation (‘tDCS’). This study shows, for the first time, a correlation between tFUS-induced mood enhancement, and reorganization of brain circuits.
New brain scans and blood tests move researchers towards more sensitive diagnosis of battlefield brain trauma and evaluation of new drugs
Granulocyte colony-stimulating factor (GCSF) is currently used to treat neutropenia due to chemotherapy and has been successfully used for patients who require bone marrow transplants. The study is the first to report on the neuroprotective effect of GCSF in vivo and showed that it improved neurological deficits that occur in the first few days following cerebral ischemia. GCSF improved long-term behavioral outcomes while also stimulating a neural progenitor recovery response in a mouse model.
Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury. The study, titled “Transplanted interneurons improve memory precision after traumatic brain injury,” was published today in Nature Communications.
John Kaczmarczyk, 58, was unconscious at the bottom of a flight of stairs in his home when his wife and son found him.
An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke (NINDS) and National Institute for Aging (NIA) to establish CONNECT-TBI—a program spanning 12 institutions which will study traumatic brain injury (TBI) and related neurodegenerative diseases.
A UCLA-led study finds that, with the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury.
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