news, journals and articles from all over the world.
Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.
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Scientists discovered a new lineage of specialized brain cells, called Hoxb8-lineage microglia, and established a link between the lineage and OCD and anxiety in mice. Their experiments proved that Hoxb8-lineage microglia prevent mice from displaying OCD behaviors and sex hormones drove symptom severity and anxiety.
Read moreIrvine, Calif., Aug. 21, 2019 — Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer’s disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it. The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer’s disease, beta-amyloid plaques – the hallmark pathology of AD – never formed.
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Brain’s immune cells form nexus between two damaging Alzheimer’s proteins Years before symptoms of Alzheimer’s disease appear, two kinds of
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