Researchers Identify a Protein That Is Critical for Wound Healing after a Central Nervous System Injury

after a Central Nervous System Injury

(New York – March 2, 2020) Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience.

Read more

Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s

The promise of flickering light to treat Alzheimer’s takes another step forward in this new study, which reveals stark biochemical mechanisms: The 40 Hertz stimulation triggers a marked release of signaling chemicals.

Read more

Genetic Variation in Individual Brain Cell Types May Predict Disease Risk

Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.

Read more

Link between brain immune cells and Alzheimer’s disease development identified

Irvine, Calif., Aug. 21, 2019 — Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer’s disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it. The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer’s disease, beta-amyloid plaques – the hallmark pathology of AD – never formed.

Read more