A Common Pathway in the Brain That Enables Addictive Drugs to Hijack Natural Reward Processing Has Been Identified by Mount Sinai

Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems.

Largest Brain Autopsy Study of Female Intimate Partner Violence Decedents Reveals Brain Injury Pathology Unlike That Seen Among Male Contact Sports Athletes

The largest brain autopsy study of women who had experienced intimate partner violence reveals substantial vascular and white matter damage in the brain, but no evidence of chronic traumatic encephalopathy (CTE), the neurodegenerative disease recognized among male contact sports athletes who sustain repeated head trauma.

Cocaine Use Disorder Alters Gene Networks of Neuroinflammation and Neurotransmission in Humans

Analysis reveals similar changes in the brain’s functioning in both humans and mouse models

Brain’s Sensitivity to Different Types of Regret May Impact Mood Disorders Like Depression, Mount Sinai Researchers Find

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual’s ability to cope with stress, and altered in psychiatric disorders like depression.

Human Cocaine and Heroin Addiction Is Found Tied to Impairments in Specific Brain Circuit Initially Implicated in Animals

Study results suggest the pre-frontal cortex-habenula circuit is potentially amenable for targeted interventions and prevention.