Protein p53 regulates learning, memory, sociability in mice

Researchers at the Beckman Institute for Advanced Science and Technology have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders.

Concurrent use of alcohol and cannabis leads to higher levels of drinking in the longer term

Co-existing use of alcohol and cannabis can lead to negative outcomes such as the development of a substance-use disorder, poor academic and occupational performance, and psychiatric disorders when compared to use of either drug alone. New research that examines simultaneous alcohol/cannabis use has found higher levels of drinking after 18 months. These results and others will be shared at the 46th annual scientific meeting of the Research Society on Alcohol (RSA) in Bellevue, Washington.

Brain’s Sensitivity to Different Types of Regret May Impact Mood Disorders Like Depression, Mount Sinai Researchers Find

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual’s ability to cope with stress, and altered in psychiatric disorders like depression.

Chula Researchers Find Extensive amounts of THC in Cannabis-Flavored Drinks The Public Is Cautioned and the Government Urged to Impose Stricter Control

Research work of a biochemistry expert at Chulalongkorn University finds that over 30% of cannabis-flavored drinks randomly tested contain higher THC levels than what is permitted. The public is warned to keep their consumption to moderate levels and that children should refrain from drinking this beverage. The government should control its consumption and warn the people of the benefit and harm of cannabis.

Mount Sinai Launches Neural Epigenomics Research Center

The Icahn School of Medicine at Mount Sinai has launched a new research center devoted to understanding how epigenomics influences the nervous system under both healthy and disease conditions. The Center for Neural Epigenome Engineering aims to dramatically expand Mount Sinai’s ability to conduct research in this field, facilitating new discoveries and the development of long-sought treatments for a variety of neurological and psychiatric disorders. Areas of expansion include chromatin biochemistry, chemical biology, protein engineering, and single-cell “omics.”

Study suggests unmedicated, untreated brain illness is likely in mass shooters

The first analysis of medical evidence on domestic mass shooters in the U.S. finds that a large majority of perpetrators have psychiatric disorders for which they have received no medication or other treatment, reports a study in the Journal of Clinical Psychopharmacology. The journal is published in the Lippincott portfolio by Wolters Kluwer.

‘Breaking the links’ in the chain of violence: Journal of Psychiatric Practice continues series on therapeutic risk management approach

With mass shootings and other seemingly meaningless acts of violence in the headlines all too frequently, strategies to assess the risk and reduce the potential for violent acts are sorely needed. The fourth in a series of five columns devoted to therapeutic risk management of violence – focusing on a method called chain analysis to identify and target pathways leading to violent thoughts and behaviors – appears in the May issue of the Journal of Psychiatric Practice. The journal is published in the Lippincott portfolio by Wolters Kluwer.

What are the links between violence and mental illness? Update from Harvard Review of Psychiatry

When there is news of a violent attack, we sometimes hear that it could be related to mental illness – which may make us ask whether the violence could have been predicted or prevented. Current research and perspectives on associations between violence and mental illness are presented in the special January/February issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.

Violence Risk Assessment in Mental Health Care – Journal of Psychiatric Practice Outlines a Therapeutic Risk Management Approach

Assessing the potential for violent behavior by patients with psychiatric disorders is an essential but challenging responsibility for mental health professionals. A five-part series currently being published in the Journal of Psychiatric Practice summarizes an expert approach to screening, assessment, and management of the risk of “other-directed violence.” The journal is published in the Lippincott portfolio by Wolters Kluwer.

With Digital Phenotyping, Smartphones May Play a Role in Assessing Severe Mental Illness

Digital phenotyping approaches that collect and analyze Smartphone-user data on locations, activities, and even feelings – combined with machine learning to recognize patterns and make predictions from the data – have emerged as promising tools for monitoring patients with psychosis spectrum illnesses, according to a report in the September/October issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.