Schizophrenia Study Suggests Advanced Genetic Scorecard Cannot Predict a Patient’s Fate

Researchers at the Icahn School of Medicine at Mount Sinai found that a tool commonly used in research for evaluating a person’s genetic risk for a disease, called a polygenic risk score, was no better at predicting the outcome of a schizophrenia patient’s disease over time than written reports. The results raise important questions about the use of polygenic risk scores in real-world, clinical situations, and also suggest that a doctor’s written report may be an untapped source of predictive information.

ASU health economist studies effects of mental illness disclosure in the workplace

A person with a serious mental illness must confront the difficult decision of whether to reveal their disorder in their workplace. Disclosing their diagnosis might create stigma, but it could also mean additional support. Adding to the delicate balancing act…

Researchers identify characteristics of highest utilizers for mental health hospital services

Dropping out of high school, having schizophrenia, or being diagnosed with a co-occurring personality disorder increases the likelihood of someone becoming a “high utilizer” of inpatient psychiatric hospital services, according to a new study by researchers at UTHealth. A high utilizer is someone who has been admitted three or more times within one year.

Mental health app equally effective, half the cost

Digital mental health apps and internet-based treatments could overcome both access problems and provider shortages. But these apps have yet to be adopted in the U.S. healthcare system. One reason is that these apps need payment and reimbursement models that would enable broad adoption.

Researchers at the University of Washington School of Medicine recently published results to help propel policymakers to create these payment models. They proved that an app to help people with serious mental illness was just as effective as a clinic-based group intervention for half the cost.

Virginia Tech researchers uncover mechanisms that wire the brain’s cerebral cortex

A research team at the Fralin Biomedical Research Institute at VTC has identified the type of brain cell that produces a protein that is crucial for the formation of inhibitory circuits in the brain. This insight could one day help scientists establish the basis for developing new drugs that mature or repair cellular networks.

Jerold Chun among world’s most highly cited researchers

Jerold Chun, M.D., Ph.D., a professor and senior vice president at Sanford Burnham Prebys Medical Discovery Institute, has been named a “Highly Cited Researcher” by Clarivate, the global analytics company. The honor recognizes researchers who have demonstrated a significant influence in their chosen field of study through the publication of multiple works that have been cited by their peers.

Lack of Motivation the Most Central Domain for Successful Treatment of Schizophrenia Symptoms

A recent conceptual development in schizophrenia is to view its manifestations as interactive networks rather than individual symptoms. Negative symptoms, which are associated with poor functional outcome and reduced rates of recovery, represent a critical need in schizophrenia therapeutics. MIN101…

Mount Sinai Researchers Find Social Isolation During Key Developmental Windows Drives Long-Term Disruptions in Social Behavior

MEDIA ADVISORY Nature Communications study UNDER EMBARGO UNTIL: Friday, February 21 at 5:00pm EST Mount Sinai Researchers find social isolation during key developmental windows drives long term changes to activity patterns of neurons involved in initiating social approach in an…

Flickering Light Mobilizes Brain Chemistry That May Fight Alzheimer’s

The promise of flickering light to treat Alzheimer’s takes another step forward in this new study, which reveals stark biochemical mechanisms: The 40 Hertz stimulation triggers a marked release of signaling chemicals.

Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders

A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered.

Study Suggests Early-Life Exposure to Dogs May Lessen Risk of Developing Schizophrenia

Ever since humans domesticated the dog, the faithful, obedient and protective animal has provided its owner with companionship and emotional well-being. Now, a study from Johns Hopkins Medicine suggests that being around “man’s best friend” from an early age may have a health benefit as well — lessening the chance of developing schizophrenia as an adult.

For better research results, let mice be mice

Animal models can serve as gateways for understanding many human communication disorders, but a new study from the University at Buffalo suggests that the established practice of socially isolating mice for such purposes might actually make them poor research models for humans, and a simple shift to a more realistic social environment could greatly improve the utility of the future studies.