A new software tool makes it easier to study relationships between a host, its microbiome and pathogens like HIV or SARS-CoV-2.
Article title: Single-cell analyses of human pancreas: characteristics of two populations of acinar cells in chronic pancreatitis Authors: Brandon M. Blobner, Jami L. Saloman, Celeste A. Shelton Ohlsen, Randall Brand, Robert Lafyatis, Rita Bottino, Martin Wijkstrom, Amer H. Zureikat, Kenneth…
Toxicological Sciences delivers cutting-edge research in toxicology in the areas of clinical and translational toxicology, emerging technologies, and more in the August 2021 issue.
By sequencing the RNA of individual cells within multiple benign and cancerous kidney tumors, researchers from the University of Michigan Rogel Cancer Center have identified the cells from which different subtypes originate, the pathways involved and how the tumor microenvironment impacts cancer development and response to treatment.
UNLV researcher Edwin Oh and colleagues have implemented wastewater surveillance programs to screen samples for the presence of COVID-19 and to extract the RNA from the SARS-COV-2 virus to find targets that make vaccines more effective.
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease.
Many viruses mutate so quickly that identifying vaccines or treatments is like trying to hit a moving target. Now, scientists report a new technique that can detect minor changes in RNA sequences. They present their results today at the American Chemical Society Fall 2020 Virtual Meeting & Expo.
Article title: Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19 Authors: Jeremy W. Prokop, Rama Shankar, Ruchir Gupta, Mara L. Leimanis, Derek Nedveck, Katie Uhl, Bin Chen, Nicholas L. Hartog, Jason Van Veen, Joshua S. Sisco, Olivia…
Scientists at Berkeley Lab and Stanford have joined forces to aim a gene-targeting, antiviral agent called PAC-MAN against COVID-19.
Hoping to refine the usefulness of RNA sequencing, a team of researchers reviewed a database of RNA sequencing results in non-clinically-accessible tissues from organs like the brain and heart. This helped them identify differences between tissues that were well expressed to help identify when clinically-accessible tissues like blood and skin samples are most useful and when they are not.