news, journals and articles from all over the world.
From artificial intelligence (AI) and data integration to natural language processing and statistics, the Cedars-Sinai Department of Computational Biomedicine is utilizing the latest technological advances to find solutions to some of the most complex healthcare issues.
Mac Gilliland, assistant professor of chemistry and Mary Elizabeth Anderson, professor of chemistry, will work with engineers and scientists at 908 Devices, a mass spec manufacturer in Boston. At least a dozen Furman undergraduate students will also work on the project, giving them experience in chemistry, device manufacturing and commercialization that few students at undergraduate institutions have.
FLASH is a targeted radiation therapy that kills tumor cells while sparing healthy tissue and delivers a short, intense burst of radiation in a single appointment. Corie Ralston from Lawrence Berkeley National Laboratory will present her team’s research using X-ray footprinting mass spectrometry to investigate the mechanisms that make FLASH a powerful cancer killer at ACA’s 73rd annual meeting, July 7-11.
PNNL scientists are creating new ways to learn more about the vast sea of unknown compounds.
Article title: Circadian gene expression in mouse renal proximal tubule Authors: Molly A. Bingham, Kim Neijman, Chin-Rang Yang, Angel Aponte, Angela Mak, Hiroaki Kikuchi, Hyun Jun Jung, Brian G. Poll, Viswanathan Raghuram, Euijung Park, Chung-Lin Chou, Lihe Chen, Jens Leipziger,…
Meteorites can be used to peek back in time or at the earliest forms of life. Today, scientists report results of the most detailed analyses yet on the organic material of two meteorites. They will present their results at ACS Spring 2023.
One study, led by the Toker group from Bar-Ilan University in Israel, observed peptide bond formation in clusters containing four serine dipeptides that were heated up by collisions. However, they found no evidence for the same process occurring in serine clusters. In that work they concluded that if two serine molecules can bind together to form a dipeptide, then the next stages of polymerization could probably occur readily.
A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease – alcohol-associated hepatitis.
The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.
A new tool to identify small molecules offers benefits for diagnostics, drug discovery, and fundamental research.
At the 2022 AACC Annual Scientific Meeting & Clinical Lab Expo, laboratory medicine experts will present the cutting-edge research and technology that is revolutionizing clinical testing and patient care.
The July issue of SLAS Discovery is now available Open Access on ScienceDirect.
Scientists at The University of Alabama in Huntsville (UAH), a part of the University of Alabama System, plan to research new fuels for hypersonic vehicles once chromatography/mass spectroscopy equipment arrives later this year at the Propulsion Research Center (PRC).
A team led by researchers at the University of Washington Tacoma, UW and Washington State University Puyallup have discovered a chemical that kills coho salmon in urban streams before the fish can spawn.
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease.
The October edition of SLAS Discovery features the cover article, “A Critical and Concise Review of Mass Spectrometry Applied to Imaging in Drug Discovery” by Richard J. A. Goodwin Ph.D. (AstraZeneca), Zoltan Takats Ph.D. (Imperial College London), and Josephine Bunch, Ph.D. (National Physical Laboratory).
A new method for rapid and inexpensive analysis of the chemical composition of blood samples may hasten the early diagnosis of diseases. The first application to be tested will be the early detection of various cancerous tumors based on blood tests.
Scientists have deployed artificial intelligence to identify more of the billions of metabolites that are currently unknown. The small molecules underlie and inform every aspect of our lives, including energy production, the fate of the planet, and our health. “Beast Mode” helps explain how they did it.
Berkeley Lab scientists have made a surprising discovery that could help explain our risk for developing chronic diseases or cancers as we get older, and how our food decomposes over time.
Scientists have taken an unprecedented look at proteins involved in endometrial cancer, commonly known as uterine cancer. The study offers insights about which patients will need aggressive treatment and which won’t, and offers clues about why a common cancer treatment is not effective with some patients.
The first hours of a lithium-ion battery’s life largely determine just how well it will perform. In those moments, a set of molecules self-assembles into a structure inside the battery that will affect the battery for years to come. Now scientists have witnessed the formation of the solid-electrolyte interphase at a molecular level.
Using a new “non-targeted” approach, University of Washington and UW Tacoma researchers screened samples from multiple regions of Puget Sound to look for potentially harmful compounds that might be present.
A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by scientists at the U.S. Department of Energy’s Pacific Northwest National Laboratory and Indiana University School of Medicine.
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