Gene Editing | sciencenewsnet.in

Light-Activated ‘CRISPR’ Triggers Precision Gene Editing and Super-Fast DNA Repair

June 17, 2020 sarah Jonas Cancer, CRISPR, Dna Repair, Gene Editing

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

Feature

Scientists Aim Gene-Targeting Breakthrough Against COVID-19

June 4, 2020 sarah Jonas Antiviral Compounds, Antiviral Drugs, Bioengineering, Chemistry, Chemistry & Materials, Coronavirus, COVID-19, CRISPR, Department of Energy (DOE), Department of Energy Office of Science, Epithelial Cells, flu, Gene Editing, Gene Therapy, Gene Therapy Drugs, human cells, Infectious Disease, Influenza, Medicine, Medicine & Health: Infectious/Emerging Diseases., Molecular Foundry, Nanomaterials, Nanoscience, Nanoscience & Technology, Nucleotides, Pandemic, Pandemic Flu, Peptide, Peptoids, Pneumonia, Polymers, preclinical research, respiratory ailments, Respiratory Infections, Respiratory Therapy, RNA Biology, Rna Editing, RNA enzyme, RNA sequencing, self-assembling RNA, Stanford University, Stanford University School of Medicine, Transfection, Upper Respiratory Infection, Viral Infections, viral mutations, Viral Replication, Virus

Scientists at Berkeley Lab and Stanford have joined forces to aim a gene-targeting, antiviral agent called PAC-MAN against COVID-19.

Research Results

Next Frontier in Bacterial Engineering

May 29, 2020 sarah Jonas Gene Editing

A new technique overcomes a serious hurdle in the field of bacterial design and engineering

Researchers develop method to identify proteins that enable highly efficient bacterial design

Approach has potential to boost efforts in bacterial design to tackle infectious diseases, bacterial drug resistance, environmental cleanup and more

Announcement

Grant will help scientists break new ground in gene editing

May 18, 2020 sarah Jonas CRISPR, Gene Editing, Genetics, Iowa State, Iowa State University, Zebrafish

A new grant from the National Institutes of Health will allow Iowa State University scientists to continue to develop gene editing technologies to model human disease in zebrafish. The research aims to build new tools to determine which genes have therapeutic potential to treat human genetic diseases that affect the cardiovascular, immune and nervous systems.

Research Results

“CRISPR: A Screener’s Guide” Headlines the March Edition of SLAS Discovery

February 24, 2020 sarah Jonas Cancer, CRISPR, Gene Editing, high-content screening, Rnai

The March edition of SLAS Discovery features the cover article, “CRISPR: A Screener’s Guide,” by Carlos le Sage, Ph.D., Steffen Lawo, Ph.D., and Benedict C.S. Cross, Ph.D., (Horizon Discovery, United Kingdom). In their review, the authors discuss how CRISPR-Cas9 systems are being used widely throughout the drug discovery process and the development of new precision medicines.

Announcement

Fred Hutch scientists host press event on future of medicine at AAAS annual meeting

February 3, 2020 sarah Jonas AAAS Annual Meeting, data science, Gene Editing, Gene Therapy

Fred Hutchinson Cancer Research Center will host a press breakfast Feb. 14 at the annual meeting of the American Association for the Advancement of Science, to be held Feb. 13-16 in Seattle.

Research Results

Hope for patients with a rare genetic condition linked to severe infections

January 22, 2020 sarah Jonas 0 Comments Gene Editing

A research team sheds light on the mechanisms underlying chronic granulomatous disease.

Research Results

Opening Up DNA to Delete Disease

January 14, 2020 sarah Jonas 0 Comments APL Bioengineering, Arizona State University, Bioengineering, Biophysics, Chromatin, CRISPR, DNA, Gene, Gene Editing, Physics, Protein, University Of Utah

Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assaults on disease. The DNA-binding editorial assistants were devised by a U.S.-based team of bioengineers, who describe their design in APL Bioengineering.

Research Results

New CRISPR-based System Targets Amplified Antibiotic-resistant Genes

December 16, 2019 sarah Jonas 0 Comments Antibiotic Resistance, Antibiotic-resistant bacteria, CRISPR, Gene Editing

Researchers have developed a new CRISPR-based gene-drive system that more efficiently inactivates a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.”

Research Results

Researchers clear the path for ‘designer’ plants

November 18, 2019 sarah Jonas 0 Comments Food Production, Gene Editing

A team of researchers at the University of Georgia has found a way to identify gene regulatory elements that could help produce “designer” plants and lead to improvements in food crops at a critical time. They published their findings in two separate papers in Nature Plants.

Research Results

Scientists unveil search-and-replace genome editing

November 1, 2019 sarah Jonas 0 Comments CRISPR, CRISPR gene editing, crispr methods, Gene Editing, Synthetic Biology

Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.