Hijacking the Hijackers: Engineering Bacterial Viruses to Genetically Modify their Hosts

Most methods of editing bacterial genomes use plasmids to transfer DNA between bacterial cells, but this approach isn’t always efficient in mixed microbial communities. This research instead developed a new phage-based DNA delivery tool that leverages these viruses’ ability to inject DNA into host bacteria. The researchers also used this tool to edit individual genes inside a target host organism within a living microbial community.

Pitt researchers led the largest-ever series of phage therapy case studies

In a new paper published today in the journal Clinical Infectious Diseases, a team led by researchers from the University of Pittsburgh and the University of California San Diego report 20 new case studies on the use of the experimental treatment, showing the therapy’s success in more than half of the patients.

CUR Health Sciences Division Announces 2021 NCUR Presentation Awardees

CUR’s Health Sciences Division announces the 2021 recipients of its NCUR Presentation Awards. The awards cover the cost of registration for undergraduates presenting original research at the 2021 National Conference on Undergraduate Research.