Most methods of editing bacterial genomes use plasmids to transfer DNA between bacterial cells, but this approach isn’t always efficient in mixed microbial communities. This research instead developed a new phage-based DNA delivery tool that leverages these viruses’ ability to inject DNA into host bacteria. The researchers also used this tool to edit individual genes inside a target host organism within a living microbial community.
Tag: Phages
A disinfectant spray that deploys “billions of tiny soldiers”
Researchers have created a powerful new weapon against bacterial contamination and infection by developing a way to spray bacteriophages – harmless viruses that eat bacteria – onto food and other materials to rid them of harmful pathogens.
Pitt researchers led the largest-ever series of phage therapy case studies
In a new paper published today in the journal Clinical Infectious Diseases, a team led by researchers from the University of Pittsburgh and the University of California San Diego report 20 new case studies on the use of the experimental treatment, showing the therapy’s success in more than half of the patients.
Trained Viruses Prove More Effective at Fighting Antibiotic Resistance
Research reveals that phage viruses that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope for the antibiotic resistance crisis, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.
CUR Health Sciences Division Announces 2021 NCUR Presentation Awardees
CUR’s Health Sciences Division announces the 2021 recipients of its NCUR Presentation Awards. The awards cover the cost of registration for undergraduates presenting original research at the 2021 National Conference on Undergraduate Research.