A research team sheds light on the mechanisms underlying chronic granulomatous disease.
Tag: Gene Editing
Opening Up DNA to Delete Disease
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assaults on disease. The DNA-binding editorial assistants were devised by a U.S.-based team of bioengineers, who describe their design in APL Bioengineering.
New CRISPR-based System Targets Amplified Antibiotic-resistant Genes
Researchers have developed a new CRISPR-based gene-drive system that more efficiently inactivates a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.”
Researchers clear the path for ‘designer’ plants
A team of researchers at the University of Georgia has found a way to identify gene regulatory elements that could help produce “designer” plants and lead to improvements in food crops at a critical time. They published their findings in two separate papers in Nature Plants.
Scientists unveil search-and-replace genome editing
Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.