GW Wins Contract to Develop Antidote-Bearing Organisms to Protect Against Biological, Chemical Threats

The George Washington University has been awarded a $3.6 million contract to genetically modify commensal organisms to produce antidotes for harmful biological and chemical agents, such as anthrax, Ebola, and even COVID-19.

Research to Prevent Blindness and Association of University Professors of Ophthalmology Announce 2022 Recipient of RPB David F. Weeks Award for Outstanding Vision Research

Donald Zack, MD, PhD, is recognized for ground-breaking contributions to the field of vision research, funded by Research to Prevent Blindness, an anonymous donor, and the Association of University Professors of Ophthalmology.

Genetically Engineered Nanoparticle Delivers Dexamethasone Directly to Inflamed Lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue. Inflammation was completely treated in mice given the nanoparticles, at a drug concentration where standard delivery methods did not have any efficacy.

Synthetic Biology and Machine Learning Speed the Creation of Lab-Grown Livers

Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine learning algorithm to create human liver organoids with blood and bile handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

International Group of Scientists Explain the Advantages of Using Metabolic Engineering to Address Hidden Hunger

In a perspective paper, “Multiplying the efficiency and impact of biofortification through metabolic engineering,” published in Nature Communications, an international team of scientists, led by Ghent University, explain how plant genetic engineering can help to sustainably address micronutrient malnutrition.

New Technique Helps Solve a Long-Standing Obstacle for Microbial Genetic Engineering

Scientists can alter genes and transfer them from one organism to another using genetic engineering. To do this, genetic engineers use DNA recombination techniques to move fragments of DNA between organisms. Scientists can then modify the gene however they want. This process is called. Now scientists have developed a fast method to find new proteins involved in DNA recombination that can improve the efficiency of genetic engineering.

Foxglove plants produce heart medicine. Can science do it better?

Biologist Zhen Wang’s team recently published a pair of papers detailing characteristics of cardiac glycosides in two foxglove species. “This kind of study is important because we first have to know the accurate structure of natural compounds before we can explore their medicinal effects,” she says.

Russian expert is ready to comment on the coronavirus

Pavel Volchkov heads the Genome Engineering Lab at the Moscow Institute of Physics and Technology (MIPT), that has several key projects, all of them involving genome editing mediated by the CRISPR/Cas technology. Discovered just a few years ago, CRISPR/Cas has…