Oral Probiotic Delivers Colitis Treatment Directly to Gut in Multiple Animal Models

Article title: Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models Authors: Emelie Öhnstedt, Cristian Doñas, Kristel Parv, Yanhong Pang, Hava Lofton Tomenius, Macarena Carrasco López, Venkata Ram Gannavarapu, Jacqueline Choi, Maria Ovezik, Peter Frank, Margareth…

Mount Sinai Launches the Brain and Body Research Center, Among the First in the U.S.to Focus Solely on How the Brain and Body Interact

Have you ever experienced a stressful time in your life and then caught a cold, or wondered why you feel sad and depressed when you’re sick? It turns out that it’s not all in your head.

Recent research spanning the fields of neuroscience and immunology suggests that when the brain senses a threat in the environment—whether it be physical, psychological, or social—it sends signals via a complex network of peripheral nerves that mobilize the immune system, readying it to protect us from injury.

Irritable Bowel Syndrome: Mark Pimentel, MD

Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder, affecting 10-15% of the world’s population. Approximately two-thirds of those who suffer from IBS are women. The disease can have mild forms or cause severe debilitation as diarrhea alternates with constipation. Severe cramping and bloating also are common. Because chronic IBS is so debilitating, it often disrupts the daily lives of people with this disorder.

Mount Sinai Researchers Unveil Mechanisms to Prevent Crohn’s Disease and First Study Linking Metals Exposure w/ IBD

In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.