Tag: Genetic Mutation

Research Identifies Potential Genetic Cause for MIS-C Complication Following COVID-19 Infection

sarah JonasResearch Results

New research findings have revealed an underlying genetic cause for why some children who have had COVID-19 infection develop Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but potentially life-threatening disease.

The findings, published in Science, are the first potential genetic cause identified for MIS-C, a disease that typically occurs about four weeks after COVID-19 infection and has broad symptoms such as fever, vomiting and inflammation of the heart muscle that can lead to hospitalization. States have reported about 9,000 MIS-C cases, with 71 deaths, according to most recent Centers for Disease Control and Prevention numbers.

New technique makes gene editing at scale possible in animals, turning years of work into days and making new kinds of genetic experiments possible

sarah JonasResearch Results

A new gene editing technique developed by University of Oregon researchers compresses what previously would have been years of work into just a few days, making new kinds of research possible in animal models.

For Neurons, Where They Begin Isn’t Necessarily Where They End

sarah JonasResearch Results

Scientists at UC San Diego School of Medicine and Rady Children’s Institute of Genomic Medicine describe novel methods for inferring the movement of human brain cells during fetal development by studying healthy adult individuals who have recently passed away from natural causes.

Gene Mutation Weakens Virus-Fighting Protein in the Gut Causing Rare Inflammatory Bowel Disease

sarah JonasResearch Results

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease. The discovery of the mutation, which weakens the activity of a protein linked to how the immune system fights viruses in the gut, may help researchers pinpoint the cause of more common bowel diseases, investigators say.

Researchers Discover New Variant of COVID-19 Virus in Columbus, Ohio

sarah JonasResearch Results

Scientists have discovered a new variant of SARS-Cov-2, the virus that causes COVID-19. It carries a mutation identical to the U.K. strain, but it likely arose in a virus strain already in the U.S. The researchers also report the evolution of another U.S. strain that acquired three other gene mutations not previously seen together in SARS-CoV2.

Mount Sinai Researchers Uncover New Molecular Drivers of Parkinson’s Disease

sarah JonasResearch Results

New Approach Will Lead to a Better Understanding of Most Cases