A prespecified secondary analysis of the MINT (Myocardial Ischemia and Transfusion) trial estimated the effect of 4 strategies to inform an optimal hemoglobin threshold for transfusion among anemic patients suffering from myocardial infarction (MI).
Tag: Hemoglobin
Base editing shows potential superiority for curing sickle cell disease
Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease and beta thalassemia. Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard found base editing increased fetal hemoglobin production in a new treatment.
St. Jude finds NLRP12 as a new drug target for infection, inflammation and hemolytic diseases
Scientists at St. Jude Children’s Research Hospital found key “on” switch, NLRP12, for innate immune cell death in diseases that cause red blood cells to rupture, which can lead to inflammation and multi-organ failure.
Red Blood Cell Units From Female Blood Donors Do Not Increase Risk of Death of Transfused Patients
A study from Karolinska Institutet in Sweden sheds new light on the question of whether the sex and previous pregnancy of blood donors affects survival in patients who receive red blood cell transfusions.
Penguin hemoglobin evolved to meet oxygen demands of diving
Experiments on ancient proteins reveal evolution of better oxygen capture, release
Measuring Hemoglobin Levels with AI Microscope, Microfluidic Chips
A complete blood count can help ascertain the health of a patient and typically includes an estimate of the hemoglobin concentration, which can indicate several conditions, including anemia, polycythemia, and pulmonary fibrosis. In AIP Advances, researchers describe a new AI-powered imaging-based tool to estimate hemoglobin levels. The setup was developed in conjunction with a microfluidic chip and an AI-powered automated microscope that was designed for deriving the total as well as differential counts of blood cells.