New research shows that Multiple Sclerosis (MS) patients undergoing anti-CD20 (aCD20) treatment – which depletes the B cells that contribute to the MS attacks – are able to mount robust T-cell responses to the mRNA COVID-19 vaccines, despite having a muted antibody response to the vaccines.
PHILADELPHIA – It was a scientific discovery 16 years ago that paved the way for creation of lifesaving vaccines when the COVID-19 pandemic spread across the globe in 2020. Now, the two Penn Medicine researchers behind the findings are again being recognized for their innovative and monumental work, which has ushered in a new era of vaccine technology.
PHILADELPHIA – For their landmark research that set a foundation for the mRNA SARS-CoV-2 vaccines, Drew Weissman, MD, PhD, the Roberts Family Professor of Vaccine Research, and Katalin Karikó;, PhD, an adjunct professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania and a senior vice president at BioNTech, have been selected to receive the 2021 Albany Prize.
Antibodies aren’t the only immune cells needed to fight off COVID-19 — T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine.
In a new study from Beth Israel Deaconess Medical Center researchers evaluated the immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women who received either the Pfizer or Moderna COVID-19 vaccines. They found that both vaccines triggered immune responses in pregnant and lactating women.
Chulalongkorn University has taken a bold step in commutating its transformation to an innovation-centric university with its “Innovations for Society” campaign. The campaign uses a short movie to inform the public about the various innovations that Chula has successfully developed to fight the COVID-19 pandemic, as part of Chula’s mission to play a leading role in “Creating Knowledge and Innovation to Promote Sustainable Development for Society”.
The 2021 Warren Alpert Foundation Prize has been awarded to scientists Lynne Maquat and Joan Steitz for seminal discoveries in the biology and function of RNA, the workhorse molecule of cells. Their discoveries have reshaped the understanding of RNA’s myriad roles in healthy cell function and in disease-causing dysfunction and have informed the conceptualization and design of RNA-based therapies in various stages of development.
接受第二剂信使RNA或mRNA COVID-19疫苗10天后，与未接种COVID-19疫苗的患者相比，无症状COVID-19感染者检测为阳性和在不知不觉中传播COVID-19的可能性大幅降低。Pfizer-BioNTech和Moderna信使RNA COVID-19疫苗已在美国获得紧急使用授权。
Dez dias após receber uma segunda dose de uma vacina para COVID-19 de RNA mensageiro, ou mRNA, pacientes sem sintomas de COVID-19 têm muito menos probabilidade de apresentar teste positivo e espalhar COVID-19 inadvertidamente, em comparação com pacientes que não foram vacinados para COVID-19.
Researchers reporting in ACS’ Nano Letters have developed a hydrogel that, when injected into mice with melanoma, slowly released RNA nanovaccines that shrank tumors and kept them from metastasizing.
Israel’s Technion will award an honorary doctorate to Pfizer CEO and Chairman Dr. Albert Bourla, for leading the development of the novel vaccine against SARS-CoV-2, the virus that causes COVID-19. The honorary doctorate will be conferred at the Technion Board of Governors meeting in November 2021.
But sometimes ribosomes get stuck or stall on roadblocks along defective mRNA molecules. New research from Washington University in St. Louis shows that cells monitor for ribosome collisions to determine the severity of the problem and how best to respond when things start to go awry.
Melanoma is skilled at evading therapies, with its cells going so far as to starve in order to stop the immune cells that would eradicate them. A team from the Weizmann Institute, including Prof. Yardena Samuels; the Netherlands Cancer Institute; and the University of Oslo have revealed one of melanoma’s tricks – never before seen in human cells – and a therapeutic target.
**All experts also available for interviews prior to event and EUA Advisory Committee Meetings**
**B-roll and lab photos of Drs. Weissman and Wherry shot this month, headshots of the others, and photos from Penn’s Moderna vaccine trial participants getting vaccinated, are available for use**
The National Science Foundation recently awarded Margaret Frank, assistant professor of plant biology at Cornell University, a $1.3 million Faculty Early Career Development Program grant for her study of mRNA communication in plants.
University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.