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UrduResearchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, deliver a biologic drug in response to inflammation.
Tag: CRISPR-Cas9
Gene-Editing ‘Scissor’ Tool May Also be a ‘Dimmer Switch’
In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 — as a genetic dimmer switch for CRISPR-Cas9 genes. Its role of dialing down or dimming CRISPR-Cas9 activity may help scientists develop new ways to genetically engineer cells for research purposes.
Can Gene Editing and Gene Therapy Techniques Combine to Treat Angelman Syndrome?
Babies born with a faulty maternal copy of the UBE3A gene will develop a severe neurodevelopmental disorder with no cure and limited treatments. Now, scientists show that gene editing/gene therapy techniques can be used to restore UBE3A in human neuron cultures and treat deficits in an animal model.
Jennifer Doudna Wins 2020 Nobel Prize in Chemistry
Biochemist Jennifer Doudna, a professor at UC Berkeley and faculty scientist at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab), is co-winner of the 2020 Nobel Prize in Chemistry for “the development of a method for genome editing.”