Rutgers Study Finds Abnormal Puberty Onset Related to Long-Term Health Outcomes, Including Infertility

Puberty is a critical stage in child development and can be a trying time for both children and parents. For some adolescents, however, a delay or early onset of puberty can have long-term negative effects, including future infertility. A study by principle investigate Sally Radovick, MD, explores these implications.

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As Evidence of “Hormone Disruptor” Chemical Threats Grows, Experts Call for Stricter Regulation

A growing number of chemicals in pesticides, flame retardants, and certain plastics have been linked to widespread health problems including infertility, diabetes, and impaired brain development, a set of reviews of hundreds of studies concludes.

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Pregnancy Complications in Assisted Reproduction Linked to a Specific Process

An experimental study from researchers in the Perelman School of Medicine at the University of Pennsylvania links a specific procedure – embryo culture – that is part of the assisted reproduction process (ART) to placental abnormalities, risk for preeclampsia, and abnormal fetal growth. The team, led by Marisa Bartolemei, PhD, a professor of Cell and Developmental Biology, published their findings today in Development.

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Split Ends: New studies show how DNA crossovers can drive healthy, abnormal sperm, egg cell division

Human genetic diversity wouldn’t be possible without DNA crossovers in egg and sperm cells. Two Harvard Medical School studies provide new insights into how crossovers go right–and wrong, leading to infertility, miscarriages and birth defects.

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Study suggests marijuana may impair female fertility

Female eggs exposed to THC, the psychoactive ingredient in marijuana, have an impaired ability to produce viable embryos, and are significantly less likely to result in a viable pregnancy, according to an animal study accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting. The abstract will be published in the Journal of the Endocrine Society.

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Fracking chemical may interfere with male sex hormone receptor

A chemical used in hydraulic fracturing, commonly called fracking, has the potential to interfere with reproductive hormones in men, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

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BREAK POINT

At a glance:

Experiments in worms reveal the molecular damage caused by DEHP, a chemical commonly used to make plastics flexible
DEHP interferes with proper cell division during egg formation, leads to excessive DNA breakage, alters chromosome appearance
Abnormalities help explain known link between DEHP and human birth defects, male infertility
If replicated in further research, the insights can help inform regulatory changes, consumer choice

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