Researchers Discover New Mutations in Gene Associated with Disease That Causes Weakening of the Heart

Researchers from the Intermountain Healthcare Heart Institute in Salt Lake City have identified new mutations in a gene commonly associated with non-ischemic dilated cardiomyopathy (NIDC), a disease that weakens the heart muscle, making it more difficult to adequately circulate blood to meet the body’s needs.

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New Clues as to Why Mutations in the MYH9 Gene Cause a Broad Spectrum of Disorders in Humans

Researchers have used the Drosophila embryo to model human disease mutations that affect myosin motor activity. Through in vivo imaging and biophysical analysis, they demonstrated that engineering human MYH9-related disease mutations into Drosophila myosin II produces motors with altered organization and dynamics that fail to drive rapid cell movements, resulting in defects in epithelial morphogenesis.

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Scientists Discover New Antibiotic in Tropical Forest

Scientists from Rutgers University and around the world have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a “plant probiotic,” more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants, according to a Rutgers co-authored study in the journal Nature Communications.

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