The study documented the earliest known interbreeding event between ancient human populations— a group known as the “super-archaics” in Eurasia interbred with a Neanderthal-Denisovan ancestor about 700,000 years ago. The event was between two populations more distantly related than any other recorded.Read more
A UCLA-led study reveals a new role for a gene that’s associated with autism spectrum disorder, intellectual disability and language impairment.Read more
A Rutgers-led team has developed a tool to monitor influenza A virus mutations in real time, which could help virologists learn how to stop viruses from replicating. The gold nanoparticle-based probe measures viral RNA in live influenza A cells, according to a study in The Journal of Physical Chemistry C. It is the first time in virology that experts have used imaging tools with gold nanoparticles to monitor mutations in influenza, with unparalleled sensitivity.Read more
Heart cells have tiny pores that generate electrical signals to initiate each heart beat. Structural studies of these channels are providing details how they work, how they malfunction due to different inherited mutations, and how they respond to drugs.Read more
Researchers from the Intermountain Healthcare Heart Institute in Salt Lake City have identified new mutations in a gene commonly associated with non-ischemic dilated cardiomyopathy (NIDC), a disease that weakens the heart muscle, making it more difficult to adequately circulate blood to meet the body’s needs.Read more
Researchers have used the Drosophila embryo to model human disease mutations that affect myosin motor activity. Through in vivo imaging and biophysical analysis, they demonstrated that engineering human MYH9-related disease mutations into Drosophila myosin II produces motors with altered organization and dynamics that fail to drive rapid cell movements, resulting in defects in epithelial morphogenesis.Read more
Scientists from Rutgers University and around the world have discovered an antibiotic produced by a soil bacterium from a Mexican tropical forest that may help lead to a “plant probiotic,” more robust plants and other antibiotics. Probiotics, which provide friendlier bacteria and health benefits for humans, can also be beneficial to plants, keeping them healthy and more robust. The new antibiotic, known as phazolicin, prevents harmful bacteria from getting into the root systems of bean plants, according to a Rutgers co-authored study in the journal Nature Communications.
A research team including faculty at Binghamton University and University of Colorado Denver are the first to map the molecular structure of an aggressive protein aggregate that causes acceleration of Alzheimer’s disease.Read more