Antibiotic resistant bacteria pose of the greatest threats to global public health. New research has the potential to reduce the amount of antibiotics used in the clinic and may pave the way for the discovery of new antibiotics that change growth rate and energy levels in bacteria.
Tag: Infections
Immune Cells Anchored in Tissues Offer Unique Defenses Against Pathogens and Cancers
Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.
HOW WILL HUMANS SURVIVE A GLOBAL CATASTROPHE?
One suggested way to save humankind in the event of a deadly pandemic or other extreme global catastrophe is establishing a safe refuge – on an island or in such far-out places as the moon or under water — where a portion of the human population can stay alive.
Possible new antivirals against COVID-19, herpes
The immune system fights viruses with peptides. Now, scientists have treated animal models of herpes with synthetic peptide mimics known as peptoids. These molecules could one day cure or prevent many kinds of infections, including COVID-19. They will present their results at ACS Fall 2021.
Sugars from human milk could help treat, prevent infections in newborns
Group B Streptococcus (GBS) bacteria are a common cause of blood infections, meningitis and stillbirth in newborns. Now, researchers have discovered that sugar molecules in human milk can prevent GBS infection in human cells and pregnant mice. They will present their results at ACS Fall 2021.
Large catheters, small veins, increase blood clot risk for cancer patients
A world-first study led by the University of South Australia has found that cancer patients receiving chemotherapy intravenously have more than double the risk of developing a blood clot or thrombosis if the vein is too small and the catheter occupies more than 45 per cent of the vein.

Story Tips from Johns Hopkins Experts on COVID-19
Coping with childhood anxiety amid returning to the classroom; new global tracker measures pandemic’s impact on education worldwide; Covid-19 drives innovation and evolution in patient care…
Rutgers Expert Available to Discuss Viral ‘Pandemics’ in Oceans
New Brunswick, N.J. (April 6, 2021) – Rutgers University–New Brunswick microbial oceanographer Kay D. Bidle is available for interviews on the persistent and profound impact of viral infections on algae in the oceans. These infections influence the Earth’s carbon cycle, which helps…

What’s That Growing on Your Face Mask?
Many people reuse masks and other face coverings many times without sanitizing them. That is likely because current sanitization methods can be cumbersome. A new device using a hanging rack and UV-C light can sterilize up to six masks and other items simultaneously and quickly, killing bacteria, yeasts, mold spores, and viruses. This device has shown its efficacy against pathogens including the highly-contagious E-coli, which was eradicated in about one minute.

Medieval medicine remedy could provide new treatment for modern day infections
To fight antibiotic resistance more antimicrobials are needed to treat bacterial biofilms, which protect an infection from antibiotics

Seeing is Believing: Effectiveness of Facemasks
Using flow visualization of emulated coughs and sneezes, researchers assessed the efficacy of facemasks in obstructing droplets. Loosely folded facemasks and bandana-style coverings provide minimal stopping-capability for the smallest aerosolized respiratory droplets. Well-fitted homemade masks with multiple layers of quilting fabric, and off-the-shelf cone style masks, proved to be the most effective in reducing droplet dispersal. Importantly, uncovered coughs were able to travel noticeably farther than the currently recommended 6-foot distancing guideline. Without a mask, droplets traveled more than 8 feet.

New Robot Does Superior Job Sampling Blood
In the future, robots could take blood samples, benefiting patients and healthcare workers alike. A Rutgers-led team has created a blood-sampling robot that performed as well or better than people, according to the first human clinical trial of an automated blood drawing and testing device.

New Tool Monitors Real Time Mutations In Flu
A Rutgers-led team has developed a tool to monitor influenza A virus mutations in real time, which could help virologists learn how to stop viruses from replicating. The gold nanoparticle-based probe measures viral RNA in live influenza A cells, according to a study in The Journal of Physical Chemistry C. It is the first time in virology that experts have used imaging tools with gold nanoparticles to monitor mutations in influenza, with unparalleled sensitivity.

Why It Matters: Prescription for Disaster
Bacteria are becoming increasingly resistant to antibiotics. A major cause is their overuse in both humans and animals. At the same time, a lack of financial incentives is setting back efforts to discover new classes of antibiotics. The problem is both global and local, and without new initiatives, many common medical conditions could become deadly once again.
HOW MEASLES WIPES OUT THE BODY’S IMMUNE MEMORY
Study shows measles wipes out 20 to 50 percent of antibodies against an array of viruses and bacteria, depleting a child’s previous immunity
Measles-ravaged immune system must “relearn” how to protect the body against infections
Study details mechanism and scope of this measles-induced “immune amnesia”
Findings underscore importance of measles vaccination, suggesting those infected with measles may benefit from booster shots of all previous childhood vaccines

Lung Lining Fluid Key to Elderly Susceptibility to Tuberculosis Disease
– Old lungs are not as capable as young lungs of fighting off an infection of the bacteria that causes tuberculosis (TB), placing seniors at a greater risk of developing TB. The microbe that causes this infectious disease, Mycobacterium tuberculosis (Mtb), currently kills more people in the world than any other pathogen. Texas Biomed researchers published an article in the Journal of Infectious Diseases in July 2019. The study details an experiment that took place in vitro (in the lab) and in vivo (in animals) that showed fluid in the lining of the lungs plays a big role in the elderly’s susceptibility to infection with the bacterium Mtb.