Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.
Using neutrons, researchers at Oak Ridge National Laboratory pieced together the molecular mechanics behind a peptide’s ability to deal significant damage to bacterial cells. Their findings could inform new therapeutic strategies for treating bacterial infections where antibiotics have fallen short.
Biologists have discovered an aberrant protein that’s deadly to bacteria. The discovery could help scientists unravel the lethal mechanism of certain antibiotics—and potentially point the way to future antibacterial drugs.
An experiment to study gravity at the quantum scale, insights into an antibiotic-building enzyme, and the backstory of an incredible new protein prediction algorithm are featured in this month’s roundup of science highlights.
Iowa State University researchers received a $1 million grant to study how manure management systems in livestock production may give rise to antibiotic resistance. Human, animal and environmental health interact in complex ways that influence the pace at which antibiotic resistance spreads, and the researchers hope their work will shed light on these connections.
A new cell profiling technology combines high throughput imaging and machine learning to provide a rapid, cost-effective way to determine how specific compounds act to destroy the bacterium that causes tuberculosis. It could speed discovery of anti-TB drugs and be applied to other pathogens.
Researchers fear that widespread use of antibiotics during the coronavirus pandemic will add fuel to the fire, making more common infections that were once treatable possibly life threatening.
Compounds that plants, fungi, bacteria, and animals produce can sometimes help people as well. In fact, many medicines, molecules used in research, and other useful compounds originated in nature. Learn more about recent discoveries in the fascinating field of natural products research.
Infectious disease scientists identified strains of group A streptococcus that are less susceptible to commonly used antibiotics, a sign that the germ causing strep throat and flesh-eating disease may be moving closer to resistance to penicillin and other related antibiotics known as beta-lactams.
Imagine a device that could swiftly analyze microbes in oceans and other aquatic environments, revealing the health of these organisms – too tiny to be seen by the naked eye – and their response to threats to their ecosystems. Rutgers researchers have created just such a tool, a portable device that could be used to assess microbes, screen for antibiotic-resistant bacteria and analyze algae that live in coral reefs. Their work is published in the journal Scientific Reports.
Millions of people are treated with antibiotics each year for infections or as a preventative measure. Two teams of NIBIB-funded scientists have been working to find alternative solutions for treating bacterial infections, especially antibiotic-resistant bacteria.
UC San Diego School of Medicine researchers have discovered how a new immune system works to protect bacteria from phages, viruses that infect bacteria — new information that could be leveraged to improve treatment of multidrug-resistant bacterial infections by refining phage therapy.
Bacteria are becoming increasingly resistant to antibiotics. A major cause is their overuse in both humans and animals. At the same time, a lack of financial incentives is setting back efforts to discover new classes of antibiotics. The problem is both global and local, and without new initiatives, many common medical conditions could become deadly once again.
Resistance to two critical antibiotic types, one a “drug of last resort” when all others fail against some “superbugs,” are widely distributed in Southeast Asia, raising the risk of untreatable infections, say a team of investigators led by Georgetown University Medical Center.