‘Fortunate Accident’ May Yield Immunity Weapon Against Antibiotic-Resistant Bacteria

In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing.

No Benefit Found in Using Broad-spectrum Antibiotics as Initial Pneumonia Treatment

Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans hospitalized with the disease. The study found that pneumonia patients given these medications in the first few days after hospitalization fared no better than those receiving standard medical care for the condition.

McMaster researchers uncover hidden antibiotic potential of cannabis

The research team found that CBG had antibacterial activity against drug-resistant MRSA. It prevented the ability of that bacteria to form biofilms, which are communities of microorganisms that attach to each other and to surfaces; and it destroyed preformed biofilms and cells resistant to antibiotics. CBG achieved this by targeting the cell membrane of the bacteria.

These findings in the laboratory were supported when mice with an MRSA infection were given CBG.