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UrduUC San Diego Herbert Wertheim School of Public Health and Human Longevity Study reports that epigenetic age acceleration is associated with lower odds of living to be 90 years old and could be used as a biomarker for healthy longevity and to estimate functional and cognitive aging.
Tag: GERONTOLOGY
Depression linked to consuming an inflammatory diet, increasing risk of frailty
A new study published in The Journal of Gerontology: Medical Sciences found a link between depression, diet, and the development of frailty.
Aging | Epigenetic clocks and their association with perceived discrimination and depressive symptoms
A new research paper was published in Aging (Aging-US / Albany NY) on the cover of Volume 14, Issue 13, entitled, “Epigenetic clocks and their association with trajectories in perceived discrimination and depressive symptoms among US middle-aged and older adults.”
Faecal transplants reverse hallmarks of ageing
In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the ageing process.
Low-dose Aspirin No Longer Recommended to Prevent Cardiovascular Disease
New draft recommendations from the U.S. Preventive Services Task Force recommend against taking aspirin to prevent heart attacks and strokes for most people. The Oct. 12, 2021 guidelines are based on new evidence showing that the risks of daily low-dose…
Scientists reverse age-related memory loss in mice
Scientists at Cambridge and Leeds have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age. In a study published today in Molecular…
Cognitive decline may help predict future fracture risk in women
Researchers led by the Garvan Institute of Medical Research have discovered a link between cognitive decline and a faster rate of bone loss, and found that cognitive decline over five years increased future fracture risk in women. The association between…
Fredrick Allan Clive Wright wins IADR Distinguished Scientist Award in Geriatric Oral Research
Alexandria, Va., USA – The International Association for Dental Research (IADR) announced Fredrick Allan Clive Wright, The University of Sydney, Australia, as the 2021 recipient of the IADR Distinguished Scientist Award in Geriatric Oral Research. Wright was recognized during the…
Evidence of sustained benefits of pimavanserin for dementia-related psychosis
Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published. Up to half of the 45 million people worldwide who are living with Alzheimer’s disease will experience psychotic episodes, a figure that…
Andrea Gilmore-Bykovskyi receives Rising Star Award in Health Services and Aging Research
Presented by the American Federation for Aging Research (AFAR)
New guidance on how to diagnosis and manage osteoporosis in chronic kidney disease
Patients with advanced chronic kidney disease (CKD) typically suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls. However, despite their high risk of fragility fractures,…
Medication or exercise? What works best for seniors with mild to moderate depression?
Effectiveness of physical exercise in older adults with mild to moderate depression
Think about this: Keeping your brain active may delay Alzheimer’s dementia 5 years
MINNEAPOLIS – Keeping your brain active in old age has always been a smart idea, but a new study suggests that reading, writing letters and playing card games or puzzles in later life may delay the onset of Alzheimer’s dementia…
Recent study identifies 11 candidate genetic variants for Alzheimer’s disease
LEXINGTON, Ky. (July 13, 2021) — A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare candidate variants for Alzheimer’s disease. Researchers found 19 different families in Utah that suffered…
PCORI approves $11 million for studies to boost COVID-19 vaccination among long-term care workers
Results could help boost immunization rates during and beyond pandemic among key health care workers
What is the evidence on how to improve older adults’ functional abilities at home?
A new analysis called an evidence and gap map has mapped what we know about improving the functional ability of older adults living at home or in nursing homes, retirement homes, or other long-term care facilities. A total of 548…
Tooth loss associated with increased cognitive impairment, dementia
Good oral health, including dentures, may protect against cognitive decline
Understanding frailty will lead to better care for older adults
Frailty is a better predictor than factors such as age when determining how older adults fare one year after receiving critical care. A team led by researchers from the University of Waterloo analyzed data from more than 24,000 community-dwelling older…
Aging-related conditions increase treatment burden in older cancer patients
Research finds multiple chronic conditions, rural residence main contributors to increased healthcare visits
Gene therapy in early stages of Huntington’s disease may slow down symptom progression
In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington’s…
Castration delays DNA aging
New research shows that castration of male sheep delays aging of DNA compared to intact males
“All the lonely people”: The impact of loneliness in old age on life and health expectancy
Singapore, 7 July 2021 – In 1966, The Beatles cemented the plight of lonely older people in the popular imagination with the iconic ‘Eleanor Rigby’, a song that turned pop music on its head when it stayed at number one…
Dignity support at end of life
How a two-way approach can promote quality care
New online calculator can help predict death and end-of-life care needs for older adults
Although most Canadians die from predictable causes and have health needs that can be met at home, only 20% of people receive a physician home visit in their last year of life. To help understand the changing care needs of…
The sense of smell in older adults declines when it comes to meat, but not vanilla
Contrary to what science once suggested, older people with a declining sense of smell do not have comprehensively dampened olfactory ability for odors in general – it simply depends upon the type of odor. Researchers at the University of Copenhagen…
Screening for dementia with artificial intelligence
The NIH has pledged nearly $4M to help researchers develop computer algorithms capable of detecting early warning signs of Alzheimer’s disease
The Gerontological Society of America congratulates 2021 awardees
The Gerontological Society of America (GSA) — the country’s largest interdisciplinary organization devoted to the field of aging — is proud to acknowledge the work of 26 outstanding individuals through its prestigious awards program. GSA salutes outstanding research, recognizes distinguished…
Self-reported declines in cognition may be linked to changes in brain connectivity
A team from Wayne State University recently published the results of a three-year study of cognitive changes in older adults who complained that their cognitive ability was worsening though clinical assessments showed no impairments. MRIs at 18-month intervals showed significant changes in functional connectivity in two areas of the brain.
AGS publishes updated AGS Minimum Geriatrics Competencies for Graduating Medical Students
Competencies updated using a modified Delphi method to reach a group consensus based on expert and stakeholder input and a literature review
State of the art and future directions in the clinical application of HR-pQCT in adults
A new international guidance on the clinical application of high-resolution peripheral computed tomography (HR-pQCT) offers an important overview of current clinical applications in adults and direction on the interpretation of results
FDA advisory panelist outlines issues with aducanumab’s approval for Alzheimer’s disease
Below please find a summary for a new article that will be published today in Annals of Internal Medicine . The summary is not intended to substitute for the full article as a source of information. This information is under…
Malene Hansen, PhD, and Morgan Levine, PhD, honored by AFAR
recognized with 2021 Irving S. Wright Award and Vincent Cristofalo Rising Star Award
Osteoporosis: New approach to understanding bone strength pays dividends
Osteoporosis researchers at the UVA School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our…
Research papers that omit ‘mice’ from titles receive misleading media coverage
Study suggests relationship between how scientists communicate findings and how journalists report research to public
A new model of Alzheimer’s progression
Alzheimer’s disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual…
High genetic running capacity promotes efficient metabolism with aging
Adipose tissue may have a key role in healthy aging
Calcified Tissue International announces top-cited papers
The authors of the journal’s 10 most oft-cited 2019 papers in 2019-20 have been awarded a certificate of publishing excellence; Get free online access to these notable papers until August 31
Depression in old age: Smoking and other risk factors less decisive
People who smoke, suffer from high blood pressure, obesity, or diabetes are not only at greater risk of suffering a stroke, heart attack, or dementia. For them, the risk of being affected by depressive mood or depression also increases. The…
New analysis examines survival of older patients who undergo heart transplantation
Advanced age is often considered a contraindication for heart transplantation, but a new study published in the Journal of the American Geriatrics Society (JAGS) found that post-heart transplant survival among recipients aged ?70 years is not inferior to that of…
Heart transplants: Age is no barrier to successful surgery
Journal of the American Geriatrics Society research summary
The Indiana Biosciences Research Institute deploys Insilico PandaOmics AI for target discovery
Insilico Medicine collaborates with the Indiana Biosciences Research Institute to apply novel artificial intelligence-powered approaches to multi-omics data analysis and discovery of potential therapeutic targets
Osteoporosis detection by a simple physical function test
Osteoporosis is a condition that does not exhibit symptoms until there is a bone fracture, so it is said that there is a high percentage of people who remain unaware of their condition. When people are unaware their bones have…
New heart metric may increase survival for heart-failure patients
A new physiological measurement of heart function developed at UVA Health could improve survival for people with heart failure by identifying high-risk patients who require tailored treatments, a new study suggests. The study is the first to show a survival…
Alzheimer’s Drug Discovery Foundation statement on FDA approval of aducanumab
New York, NY (June 7, 2021) – Today’s FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer’s disease reflects years of significant advances in Alzheimer’s research. This is the first new Alzheimer’s drug approved in 17…
Fragility fractures cost European health care systems €56.9 billion annually
New International Osteoporosis Foundation report provides unique overview of osteoporosis in Europe, revealing the enormous disease burden and an unacceptable treatment gap; 71% of women at high risk of fracture are not receiving much-needed medication
Football and team handball training may increase health span and, ultimately, lifespan
In the quest for healthy aging and longer lifespan, Danish researchers at the University of Southern Denmark have collaborated with Swedish researchers at Karolinska Institutet to explore the anti-aging effects of football and team handball training
Researcher gets $2.7 million grant to study seasonal and universal vaccination in aged populations
ATLANTA–Dr. Sang-Moo Kang, professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.7 million federal grant to study seasonal and universal vaccination in elderly populations with pre-existing immunity to influenza viruses. The grant from…
Alzheimer’s disease raises the risk of severe COVID-19 and death from this viral disease
Patients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80, according to a study by Brazilian researchers
Prior COVID-19 infection reduces infection risk for up to 10 months
The risk of being infected with SARS-CoV-2, the virus that causes COVID-19, is substantially reduced for up to 10 months following a first infection, according to new findings from the Vivaldi study led by UCL researchers
High-intensity strength and impact training attenuates skeletal aging
The tibial bone properties of middle-aged and older male sprint athletes were followed over 10 years