New guidance on how to diagnosis and manage osteoporosis in chronic kidney disease

Patients with advanced chronic kidney disease (CKD) typically suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls. However, despite their high risk of fragility fractures,…

State of the art and future directions in the clinical application of HR-pQCT in adults

A new international guidance on the clinical application of high-resolution peripheral computed tomography (HR-pQCT) offers an important overview of current clinical applications in adults and direction on the interpretation of results

Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen provide better pain control and have fewer adverse effects than codeine, a commonly prescribed opioid, when prescribed after outpatient surgery, according to new research published in CMAJ (Canadian Medical Association Journal) https:/ /…

Study examines care received by patients with knee osteoarthritis

New research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and knee injections, and few were treated by rheumatologists, physiatrists, or pain specialists. The study, which is…

Fragility fractures cost European health care systems €56.9 billion annually

New International Osteoporosis Foundation report provides unique overview of osteoporosis in Europe, revealing the enormous disease burden and an unacceptable treatment gap; 71% of women at high risk of fracture are not receiving much-needed medication

Researchers discover potential new approach to treating psoriatic joint inflammation

(SACRAMENTO, Calif.) – An international team of researchers, led by UC Davis Health , has developed a new therapeutic approach to treating psoriatic arthritis , a chronic inflammatory disease affecting the joints. Using a novel chemical blocker targeting chemokine proteins,…

Blood test detects childhood tumors based on their epigenetic profiles

A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These “liquid biopsy” analyses exploit the unique epigenetic…

NTU Singapore scientists turn aquaculture waste into new biomaterial for tissue repair

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a new biomaterial made entirely from discarded bullfrog skin and fish scales that could help in bone repair. The porous biomaterial, which contains the same compounds that are predominant in…

Proteomics reveals how exercise increases the efficiency of muscle energy production

Mitochondria are the cell’s power plants and produce the majority of a cell’s energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these…

How to manage osteoporosis in hematologic stem cell transplant recipients

IOF Cancer & Bone Disease Working Group summary and algorithm outlines main recommendations to maintain bone health in HSCT patients: includes guidance for bone assessment, management and treatment as well as dietary and lifestyle recommendations.