Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.
Tag: MUSCULATURE
Sleep twitches facilitate motor cortex development in rats
Sleep twitches enrich coding of sensory information, lay groundwork for later motor functions
Yoga helps reduce work-related stress
Physical relaxation through yoga or other practices can help reduce work-related stress, according to an analysis of studies conducted in healthcare staff. The analysis, which is published in the Journal of Occupational Health , included 15 randomized clinical trials with…
Muscles retain positional memory from fetal life
New perspectives on the pathological mechanisms of muscle diseases and regenerative medicine development
A new reporter mouse line to detect mitophagy changes during muscle tissue loss
Mitophagy reporter mouse could provide cues for future therapies and rehabilitation strategies
Autopsy Study of Patients With/Without COVID-19
JAMA Neurology
Osteoarthritis linked to higher Parkinson’s disease risk
A study published in Arthritis Care & Research has uncovered an elevated risk of Parkinson’s disease in individuals with osteoarthritis. The retrospective study using Taiwan’s Longitudinal Health Insurance Database 2005 included 33,360 patients who were 50-64 years old and had…
Study examines care received by patients with knee osteoarthritis
New research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and knee injections, and few were treated by rheumatologists, physiatrists, or pain specialists. The study, which is…
MLB ‘FEVER’ — improved elbow MRI view for Major League Baseball pitchers
Flexed elbow valgus external rotation (FEVER) view improves MRI evaluation of ulnar collateral ligament in Major League Baseball throwing athletes
ALS development could be triggered by loss of network connections in the spinal cord
ALS is a very severe neurodegenerative disease in which nerve cells in the spinal cord controlling muscles and movement slowly die. There is no effective treatment and the average life expectancy after being diagnosed with ALS is usually short. Because…
Danish invention preserves muscle mass in COVID-19 patients
Researchers from Aarhus University have developed electronic support stockings and tested them on bed-ridden Covid patients at Copenhagen University Hospitals. Results show that the stockings counteract a significant loss of muscle mass.
Higher incidence of carpal tunnel syndrome after bilateral oophorectomy
New study suggests the risk of severe carpal tunnel syndrome increases for women after surgery to remove the fallopian tubes and ovaries
Skeletal muscle loss exacerbated by diabetes improved with oligo DNA
Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production. However, skeletal muscle mass is reduced in some diabetics,…
Proteomics reveals how exercise increases the efficiency of muscle energy production
Mitochondria are the cell’s power plants and produce the majority of a cell’s energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these…
New study shows how to boost muscle regeneration and rebuild tissue
Salk research reveals clues about molecular changes underlying muscle loss tied to aging
Vegan and omnivorous diets promote equivalent muscle mass gain, study shows
Trials performed by researchers at the University of São Paulo with healthy young adults show that the right level of protein intake is the key to muscle health, regardless of protein source.
Icing muscle injuries may delay recovery
A study using a mouse model of eccentric contraction (*1) has revealed that icing injured muscles delays muscle regeneration. The discovery was made by a research group including Associate Professor ARAKAWA Takamitsu and then PhD. Student KAWASHIMA Masato from Kobe…
Towards a treatment for myotonic dystrophy: First 3D model with patient cells
Myotonic dystrophy is a hereditary degenerative neuromuscular disease that occurs mainly in adults, affecting about 50,000 people only in Spain. Symptoms range from difficulty walking and myotonia (great difficulty in relaxing the contracted muscles) to severe neurological problems, leading to…
New research finds advanced shoe technology reduces top race times for elite athletes
For elite runners competing in long-distance races, every second counts. So when Nike introduced “advanced shoe technology” in 2017, questions arose about whether the new design would significantly affect performances in professional sports. A new paper published in Frontiers in…
Researchers revise indicator of mobility limitation in older adults
The new cutoff values for a metric widely used by geriatricians, physical therapists and nutritionists are more accurate, facilitate early diagnosis and contribute to preventive treatment
Study shows why crossing obstacles is difficult for patients with Parkinson’s disease
The scientists detected incapacities related to gait timing and foot placement. Their discoveries serve as a basis for the development of an exercise protocol that mitigates the difficulty.
More protein doesn’t mean more strength in resistance-trained middle-aged adults
CHAMPAIGN, Ill. — A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training. The intervention involved a…
Stem cell therapy shows promise against age-related muscle loss
As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss…
Chemical cocktail creates new avenues for generating muscle stem cells
The advance could lead to the development of stem cell-based therapies for muscle loss or damage due to injury, age or disease
Predicting the likelihood of bone fractures in older men
Fractures in the vertebrae of the spine and calcification in a blood vessel called the abdominal aorta can both be visualized through the same spinal imaging test. A new study published in the Journal of Bone and Mineral Research that…
Scientists assess effects of soccer player preparation and recovery on kicking performance
Article published by Brazilian researchers in Sports Medicine presents a systematic review of scientific studies on the topic
Researchers identify barriers to use of surface electromyography in neurorehabilitation
Kessler Foundation team proposes comprehensive approach to integrating surface electromyography into clinical practice as path to improving rehabilitative care for individuals with spinal cord injury
JNCCN: New evidence on need to address muscle health among patients with cancer
Results of new study underscore the need for the development and testing of nutrition and fitness interventions, as muscle quality significantly correlates with symptom burden, healthcare utilization, and survival
Hospital admissions associated with noncommunicable diseases during COVID-19 outbreak in Brazil
What The Study Did: Researchers assessed the number of hospital admissions for noncommunicable diseases (abnormal tissue growths, metabolic diseases, cardiovascular diseases and musculoskeletal diseases) in São Paulo, Brazil, between January and June last year compared with the corresponding periods in the…
Study links kidney stones with bone problems
In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the…
Study shows opioid use among US patients with knee osteoarthritis costs 14 billion dollars in societal costs
Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research , an official journal of the American College of Rheumatology and the Association…
Treating rheumatoid arthritis with micromotors
Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren’t completely successful. Now,…
TBE patients’ lasting problems
Impaired memory, reduced motivation, and declining motor skills. These are some of the problems that may persist several years after people contract tick-borne encephalitis, a University of Gothenburg thesis shows. Tick-borne encephalitis (TBE) is caused by a virus, found in…
New drug molecules hold promise for treating fatal child disease
Scientists have identified a way to “rescue” muscle cells that have genetically mutated, paving the way to a possible new treatment for rare childhood illness such as Duchenne Muscular Dystrophy (DMD). The study, led by the Universities of Exeter and…
Certain factors are linked with an elevated risk of bone fractures
A new study published in the Journal of Bone and Mineral Research has identified various factors that may indicate whether a person faces a higher likelihood of experiencing a bone fracture over the next two decades. The study included 30,446…
Study reveals a new potential mechanism underlying loss of muscle mass during menopause
A new study conducted in collaboration between the universities of MinnA new study reveals that estrogen deficiency alters the microRNA signalling in skeletal muscle
Radiological images confirm ‘COVID-19 can cause the body to attack itself’
Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain
One in five has a mutation that provides superior resilience to cold
Almost one in five people lacks the protein α-actinin-3 in their muscle fibre. Researchers at Karolinska Institutet in Sweden now show that more of the skeletal muscle of these individuals comprises slow-twitch muscle fibres, which are more durable and energy-efficient…
The body produces new satiety factor during prolonged exercise
A drug that helps us to eat less could help the more than 650 million people around the world who live with obesity. One of the emerging drug candidates that interest researchers is the hormone GDF15 that, when given to…
Leesa M. Galatz, MD, receives honor from prestigious society for contributions to orthopedic research
The Orthopaedic Research Society (ORS) has named Leesa M. Galatz, MD, Professor and Chair of the Leni and Peter W. May Department of Orthopedic Surgery at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Health System,…
New research identifies biological causes of muscle weakness in later life
A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility. As we get…
Novel protein could reverse severe muscle wasting in disease, aging and trauma
Factor found that triggers muscle stem cells to regenerate: complete muscle replacement and movement achieved in mouse models
Notes of discomfort: Study keys in on trends in marching band members’ pain
CORVALLIS, Ore. – Marching band members in leadership roles are more likely to feel discomfort in the neck and upper back than their less experienced bandmates, who in turn are more susceptible to left-hand pain and cognitive strain, a new…
Fetal surgery for spina bifida leads to better mobility in school-age children
Follow up to landmark 2011 study shows children who had prenatal repair also have better self-care skills and are more independent up to 10 years later
Model predicts likelihood of persistent high-dose opioid use after knee surgery
A new study published in Arthritis Care & Research has identified 10 readily available clinical factors that may predict which patients will persistently use high doses of opioids in the year following knee replacement surgery. In the study of 142,089…
Sleep deprivation may exacerbate frailty’s effects on mental health in older adults
Previous studies have linked sleep deprivation and frailty with depression. A new study published in the Journal of the American Geriatrics Society that examined their combined effect suggests that short sleep intensifies the impacts of frailty on depressive symptoms. Among…
Remyelinating drug could improve vision in patients with multiple sclerosis
UC Riverside-led mouse study stresses MS treatment should be started early
Exercising muscle combats chronic inflammation on its own
Exercising lab-grown human muscle autonomously blocks the damaging effects of interferon gamma
NAD+ can restore age-related muscle deterioration
The older we grow, the weaker our muscles get, riddling old age with frailty and physical disability. But this doesn’t only affect the individual, it also creates a significant burden on public healthcare. And yet, research efforts into the biological…
Physical frailty syndrome: a cacophony of multisystem dysfunction
In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related pathophysiology underpinning the clinical…