Study examines care received by patients with knee osteoarthritis

New research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and knee injections, and few were treated by rheumatologists, physiatrists, or pain specialists. The study, which is…

Danish invention preserves muscle mass in COVID-19 patients

Researchers from Aarhus University have developed electronic support stockings and tested them on bed-ridden Covid patients at Copenhagen University Hospitals. Results show that the stockings counteract a significant loss of muscle mass.

Skeletal muscle loss exacerbated by diabetes improved with oligo DNA

Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production. However, skeletal muscle mass is reduced in some diabetics,…

Proteomics reveals how exercise increases the efficiency of muscle energy production

Mitochondria are the cell’s power plants and produce the majority of a cell’s energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation. A number of different proteins in mitochondria facilitate these…

Towards a treatment for myotonic dystrophy: First 3D model with patient cells

Myotonic dystrophy is a hereditary degenerative neuromuscular disease that occurs mainly in adults, affecting about 50,000 people only in Spain. Symptoms range from difficulty walking and myotonia (great difficulty in relaxing the contracted muscles) to severe neurological problems, leading to…

New research finds advanced shoe technology reduces top race times for elite athletes

For elite runners competing in long-distance races, every second counts. So when Nike introduced “advanced shoe technology” in 2017, questions arose about whether the new design would significantly affect performances in professional sports. A new paper published in Frontiers in…

Researchers identify barriers to use of surface electromyography in neurorehabilitation

Kessler Foundation team proposes comprehensive approach to integrating surface electromyography into clinical practice as path to improving rehabilitative care for individuals with spinal cord injury

Hospital admissions associated with noncommunicable diseases during COVID-19 outbreak in Brazil

What The Study Did: Researchers assessed the number of hospital admissions for noncommunicable diseases (abnormal tissue growths, metabolic diseases, cardiovascular diseases and musculoskeletal diseases) in São Paulo, Brazil, between January and June last year compared with the corresponding periods in the…

Study shows opioid use among US patients with knee osteoarthritis costs 14 billion dollars in societal costs

Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care & Research , an official journal of the American College of Rheumatology and the Association…

Treating rheumatoid arthritis with micromotors

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren’t completely successful. Now,…

Model predicts likelihood of persistent high-dose opioid use after knee surgery

A new study published in Arthritis Care & Research has identified 10 readily available clinical factors that may predict which patients will persistently use high doses of opioids in the year following knee replacement surgery. In the study of 142,089…

Sleep deprivation may exacerbate frailty’s effects on mental health in older adults

Previous studies have linked sleep deprivation and frailty with depression. A new study published in the Journal of the American Geriatrics Society that examined their combined effect suggests that short sleep intensifies the impacts of frailty on depressive symptoms. Among…

Physical frailty syndrome: a cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related pathophysiology underpinning the clinical…