They have used precision medicine to uncover and treat new skeletal disorders
Tag: MUSCULATURE
Army strengthens future tech with muscle-bound robots
ABERDEEN PROVING GROUND, Md. — Robotic systems packed with muscle tissue can produce never-seen-before agility and versatility, Army researchers said. Researchers with the U.S. Army Combat Capabilities Development Command, now known as DEVCOM, Army Research Laboratory are teaming with collaborators…
Exercise may protect bone health after weight loss surgery
Although weight loss surgery is a highly effective treatment for obesity, it can be detrimental to bone health. A new study published in the Journal of Bone and Mineral Research suggests that exercise may help address this shortcoming. The study…
Life expectancy and healthcare costs for patients with rheumatoid arthritis
A new study published in Arthritis & Rheumatology suggests that recent advances in the treatment of rheumatoid arthritis have prolonged patients’ lives but also increased healthcare costs. For the study, investigators examined medical claims data from the National Health Insurance…
Healthy muscles are a carrot on a string for healthy lungs
Osaka City University shows carrot-based Japanese herbal medicine “Ninjin’yoeito” helps recover muscle fibers in mice.
Visualisation reveals how a protein ‘hunkers down’ to conserve energy
A visualisation made from nearly 100,000 electron microscope images has revealed the ingenious way a protein involved in muscle activity shuts itself down to conserve energy. The protein is called myosin and it is known as a molecular motor because…
Popular weight-loss surgery in teenagers weakens bones
“Childhood obesity is a major public health issue that has increased over the last 10 years,” said lead investigator Miriam A. Bredella, M.D., professor of radiology at Harvard Medical School in Boston, Massachusetts, and vice chair of the Department of…
Study: Early, late stages of degenerative diseases are distinct
Two-phase theory applies to diseases like Alzheimer’s, Parkinson’s, muscle atrophy
Link between periodontitis and cardiovascular disease in individuals with rheumatoid arthritis
Rates of both periodontal disease and cardiovascular disease are elevated in individuals with rheumatoid arthritis. New research published in Arthritis & Rheumatology suggests that immune responses to certain bacteria that cause periodontal disease may play a role in patients’ higher…
Racket sports may worsen knee arthritis
OAK BROOK, Ill. – Racket sports like tennis and racquetball appear to accelerate knee joint degeneration in overweight people with osteoarthritis, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA). Knee…
Novel technique ‘stuns’ arthritis pain in shoulder and hip
OAK BROOK, Ill. – A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of…
VSimulators technology to develop footwear for active older people
A project that will use cutting-edge technology to develop safe and comfortable footwear for active older people has received a grant from UK Research and Innovation (UKRI). Dr Sharon Dixon and Professor James Brownjohn will use the brand new VSimulators…
Analysis reveals high burden of musculoskeletal disorders across the globe
Musculoskeletal disorders–which affect muscles, tendons, ligaments, bones, and joints–can severely affect individuals’ physical and mental health, and they’re especially prevalent among aging adults. Although many researchers are studying these conditions and their rates in different regions of the world, no…
Different outcomes by race/ethnicity among patients with COVID-19 and rheumatic disease
Among U.S. patients with rheumatic disease and COVID-19, racial/ethnic minorities had higher risks of needing to be hospitalized and put on ventilators. The findings come from an analysis published in Arthritis & Rheumatology . The analysis included data on all…
New opportunities for detecting osteoporosis
Osteoporosis can be detected through low dose computed tomography (LDCT) imaging tests performed for lung cancer screening or other purposes. A study published in the Journal of Bone and Mineral Research found that such tests can identify large numbers of…
Scientist studies the role of a muscle protein in skeletal muscle disorders
NIAMS grant supports the work of a University of Cincinnati researcher
Higher risk of future fecal incontinence after sphincter injuries
The risk of subsequent fecal incontinence and intestinal gas leakage is significantly higher among women who, during childbirth, have suffered a sphincter injury and consequent damage to the anal sphincter muscle, was shown in a new study from the University…
Brazilian researchers discover how muscle regenerates after exercise
Adaptation of muscle tissue to aerobic exercise alters the metabolism of muscle stem cells, helping them recover from injury. Findings may contribute to treatment of cachexia, sarcopenia and other conditions associated with lean mass loss
More than half of American adults with advanced MS report mistreatment by caregivers
UC Riverside-led study describes first published survey documenting nature and extent of caregiver mistreatment of this population
Damaged muscles don’t just die, they regenerate themselves
A new mechanism for muscle stem cell activation
Skeletal muscle development and regeneration mechanisms vary by gender
The functional importance of estrogen receptor beta
Physical activity and sleep in adults with arthritis
A new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthritis. In the 172-participant study, four profiles were apparent with differences characterized by variations…
LED-based UV irradiation safely prevents the loss of bone and muscle mass in mice
A research team at Nagoya University in Japan has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass.…
Finding a cure for multiple sclerosis
Biomedical scientist Seema Tiwari-Woodruff has received funding to identify compounds that can repair damaged axons
Lockdown impact: Worsening symptoms for people with bone, joint and muscle pain
Peer reviewed — survey — humans
Genetic analysis links obesity to higher rheumatoid arthritis risk
An analysis of genetic data collected from more than 850,000 individuals of European ancestry has found a link between obesity-related genes and rheumatoid arthritis. In the Arthritis & Rheumatology analysis, investigators found an increased risk of rheumatoid arthritis when body…
Is rheumatoid arthritis two different diseases?
While disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with autoantibodies, according to a new study published this week in PLOS Medicine by Xanthe Matthijssen of Leiden University Medical Center,…
Tool uses fat in bone and muscle to diagnose disease, predict falls and fractures
Doctors will soon be able to use fat to diagnose musculoskeletal disease within seconds and predict the risk of falls and fractures in older people, thanks to a world-leading tool developed by Melbourne researchers
Biomechanics: Wearing footwear with toe springs requires less muscle work
Wearing footwear with an upward curvature at the front of the shoe – known as the toe spring – requires less work from the muscles of the feet to walk than shoes with a flatter sole, according to an experimental…
Minimally invasive ultrasound-guided carpal tunnel release improves long-term outcomes
Ultrasound-guided carpal tunnel release quickly improves hand function and reduces hand discomfort, making the procedure a safe, effective, and less invasive alternative to traditional open or endoscopic surgery
New insight into how muscles and fat cells work together to make you more fit
Why does exercise training make you more fit? It’s well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood. New research published…
COVID ventilator patients can have permanent nerve damage
Prone positioning saves lives, but nerve pressure injuries impair arms and legs
Does the Mediterranean diet protect against rheumatoid arthritis?
Previous research has demonstrated a variety of health benefits associated with the Mediterranean diet, which is rich in olive oil, cereals, fruit and vegetables, fish, and a moderate amount of dairy, meat, and wine. Now results from an analysis published…
Improving the transition from pediatric to adult rheumatology care
As children with chronic rheumatic illnesses age, it’s important that they experience a smooth transition from pediatric to adult care. A study published in Arthritis Care & Research has identified certain factors that are important during this time. In the…
Muscle aging: Stronger for longer
With life expectancy increasing, age-related diseases are also on the rise, including sarcopenia, the loss of muscle mass due to aging. Researchers from the University of Basel’s Biozentrum have demonstrated that a well-known drug can delay the progression of age-related…
Ghrelin may be an effective treatment for age-related muscle loss
Conference abstract, experimental, mice
Dr. Daniel Pinto named winner of the 2020 ESCEO-IOF Pierre Meunier Young Scientist Award
The prestigious annual Award recognizes young investigators in the field who have demonstrated outstanding scientific merit early in their careers
Patients with recently discovered antibodies have more severe myasthenia gravis
A study of 181 patients at 16 sites across the country who test negative for two antibodies long known to cause muscle-weakening myasthenia gravis, found that about 15% test positive for one of two newly discovered antibodies that also attack…
Virtual IOF-ESCEO World Congress draws record attendance
The CME-accredited WCO-IOF-ESCEO 2020, from August 20-22, will feature more than 210 live and pre-recorded sessions covering new clinical research and advances in the field of osteoporosis, osteoarthritis and musculoskeletal diseases.
High intensity physical activity in early life could lead to stronger bones in adulthood
The research, which analysed data from 2,569 participants of the Children of the 90s health study, found that more time spent doing moderate-to-vigorous intensity physical activity (MVPA) from age 12 years was associated with stronger hips at age 25 years,…
Simultaneous stimulation helped a spinal cord injury patient regain the ability to walk
At the BioMag Laboratory, the first promising results have been achieved in the application of synchronised electrical and magnetic stimulation therapy when rehabilitating a paraplegic patient and restoring his ability to walk.
Researchers characterize important regulators of tissue inflammation, fibrosis and regeneration
Therapeutic manipulations of these cells hold promise for promoting muscle injury repair and improving outcomes for individuals with muscular dystrophy
Gout diagnoses rising worldwide
The prevalence of gout–a form of arthritis characterized by severe pain, redness, and tenderness in joints–increased across the world at an alarming rate from 1990 to 2017, according to an analysis published in Arthritis & Rheumatology . The analysis found…
Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker’s fracture risk. The findings are published in the Journal of Bone and Mineral Research…
Rheumatoid arthritis linked to a lower risk of type 2 diabetes
A recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other individuals, including those with other types of arthritis. The analysis, which is published in…
Adjustable lordotic expandable vs static lateral lumbar interbody fusion devices
This article by Dr. Samantha Greeley et al. is published in The Open Orthopaedics Journal, Volume 14, 2020
C-Path receives positive FDA response for drug-induced skeletal muscle injury biomarkers
The safety biomarkers, developed by C-Path’s PSTC and D-RSC, aim to provide an additional tool for detecting acute drug-induced skeletal muscle injury in phase 1 clinical trials.
Genetic testing could improve screening for osteoporosis
An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility A full genome profile can be generated for approximately £35-40 per…
Study shows genetic markers are useful in predicting osteoporotic fracture risk
Findings hold potential for cost savings while improving efficiency of screening
Fantastic muscle proteins and where to find them
Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its…