McMaster scientists pinpoint key trigger of Crohn’s disease

Researchers gleaned their results by analyzing blood and biopsy samples from two groups totalling 18 people with Crohn’s disease, comparing them to a matching number of people from two healthy control groups. A mouse model of IBD was also used. Khan said his study was the first demonstration of the interaction between serotonin, autophagy and gut microbiota in intestinal inflammation. The paper was published by Science Advances today. Sabah Haq, a PhD student who works with Khan, is first author.

Mount Sinai Neurobiologist Selected as a Howard Hughes Medical Institute Investigator

The Howard Hughes Medical Institute (HHMI) has selected Ian Maze, PhD, Associate Professor of Neuroscience, and Pharmacological Sciences, at the Icahn School of Medicine at Mount Sinai, as an HHMI Investigator.

Scientists find neurochemicals have unexpectedly profound roles in the human brain

Dopamine and serotonin are at work at sub-second speeds to shape how people perceive the world and take action based on their perception. The discovery shows researchers can simultaneously measure the activity of both dopamine and serotonin in disorders ranging from depression to Parkinson’s disease.