X-ray study explores potential of hepatitis C drugs to treat COVID-19

Researchers at the Department of Energy’s Oak Ridge National Laboratory investigated the binding properties of several hepatitis C drugs to determine how well they inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce. Inhibiting, or blocking, the protease from functioning is vital to stopping the virus from spreading in patients with COVID-19.

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Statins Reduce COVID-19 Severity, Likely by Removing Cholesterol That Virus Uses to Infect

Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why.

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Vanderbilt University Medical Center Among Top 100 Proposals for MacArthur $100 Million Grant

The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Changecompetition for a single $100 million grant to help solve one of the world’s most critical societal challenges.

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Dozens of potential anti-cancer drugs netted in massive screening study

A variety of existing drugs for treating conditions such as diabetes, inflammation, alcohol abuse, and arthritis in dogs can also kill cancer cells in the lab, according to a study by scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

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