English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduLehigh University researchers’ breakthrough could advance diagnosis and treatment of bleeding disorder and lead to improved design of left ventricular assist devices used in heart failure patients
Tag: Hematology
COVID-19 vaccination: Thrombosis can be prevented by prompt treatment
A rare syndrome has been observed in people following vaccination against Covid-19.
No-one knew if lymph vessel cells bear cilia; turns out, they’re indispensable for health
The primary cilium, an antenna-like subcellular structure (‘organelle’) protruding from the outside of many types of vertebrate cells, has an important but previously overlooked role in guiding the growth of lymphatic vessels, shows a new study.
Emergency physicians first to safely treat vaccine-induced blood clot with heparin alternative
WASHINGTON, DC — A new case report, detailed in Annals of Emergency Medicine , is the first known case of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) treated with a heparin alternative following the Centers for Disease Control and Prevention…
Study finds potential therapeutic target for pediatric acute myeloid leukemia
Novel gene variants may point the way to precision medicine for AML in children
NCCN releases new patient guidelines on anemia and neutropenia
New resource helps patients and caregivers recognize and understand blood cell production deficiencies, to better participate in their care planning; available for free at NCCN.org/patientguidelines
Toward safer stem cell transplants
For cancer patients, the use of hematopoietic stem cell transplants can be a game changer in terms of treatment and recovery. However, most people need to undergo a combination of chemotherapy and radiation before transplants become an option. A new…
Blood pressure and hemorrhagic complication risk after renal transplant biopsy
2021 ARRS Virtual Annual Meeting Scientific Electronic Exhibit found no statistically significant threshold for increased renal transplant biopsy risk based on systolic, diastolic, or mean arterial blood pressure alone
Studies suggest people with blood cancers may not be optimally protected after COVID-19 vaccination
Two new studies published in Blood suggest that the mRNA COVID-19 vaccine may have reduced efficacy in individuals with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer.
ACS Spring 2021 press conference schedule
Watch live and recorded press conferences at http://www. acs. org/ acsspring2021conferences . Press conferences will be held Monday, April 5, through Friday, April 16, 2021. Below is the schedule, which will be updated as needed. ALL TOPICS ARE STRICTLY EMBARGOED…
Studies suggest people with blood cancers may not be optimally protected after COVID-19 vaccination
Two new studies published in Blood suggest that the mRNA COVID-19 vaccine may have reduced efficacy in individuals with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer. According to researchers, these studies could help inform the…
CHOP-led Research Study Identifies Key Target in Treatment-Resistant Hemophilia A
Researchers at Children’s Hospital of Philadelphia (CHOP) have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A. The target, known as B cell activating factor (BAFF), appears to promote antibodies against and inhibitors of the missing blood clotting factor that is given to these patients to control their bleeding episodes. The findings, published in the Journal of Clinical Investigation, raise the possibility of using anti-BAFF therapies, potentially in combination with immune tolerance therapies, to tame the immune response in some patients with severe hemophilia A.
Alliance for Cancer Gene Therapy Summit 2021 features world renowned cancer researchers advancing so
James P. Allison, PhD, Carl H. June, MD and Siddhartha Mukherjee, MD Keynote April 29 Summit
Diet and exercise may increase efficacy of chemotherapy for children with cancer
Pilot study suggests nutrition improves success of pediatric leukemia treatment; national trial to launch this year
Crnic Institute discovery may explain high risk of leukemia in children with Down syndrome
Groundbreaking identification of precocious clonal hematopoiesis unlocks new lines of research and discovery for scientists
FDA approvals strengthen Octapharma USA pediatric critical care product portfolio
Octaplas™ and fibryga® receive new product labeling following FDA’s approval of BLA supplements to update therapy research; FDA expands fibryga® indication to include treatment of children under 12 years of age
One drop of blood brings progression of multiple myeloma into better view
Sensitive test opens door to personalized therapy
C-Path launches acute kidney injury project with support from FDA
Project aims to develop improved predictive and detection tools for kidney injury
Cecelia Calhoun Named Director of the Adolescent-Young Adult Sickle Cell Program at Yale Cancer Center and Smilow Cancer Hospital
Cecelia Calhoun, MD, MSPH, MBA, has been appointed Assistant Professor of Medicine (Hematology) and Assistant Professor of Pediatrics (Hematology/Oncology) at Yale Cancer Center and Smilow Cancer Hospital
Outpatient management following diagnosis of acute pulmonary embolism
Despite guidelines promoting outpatient management of patients with low-risk pulmonary embolism (PE), few patients are currently discharged home from hospital emergency departments in the United States. That is the conclusion of a study titled Outpatient Management of Patients Following Diagnosis…
Image analysis based on machine learning reliably identifies haematological malignancies
Myelodysplastic syndrome (MDS) is a disease of the stem cells in the bone marrow, which disturbs the maturing and differentiation of blood cells. Annually, some 200 Finns are diagnosed with MDS, which can develop into acute leukaemia. Globally, the incidence…
Study: Older multiple myeloma patients can be spared of long-term steroids
Phase III study shows benefits of using age and functional status to guide, modify treatment approach
A leap forward in research on CAR T cell therapy
Cellular engineering makes it possible to target the therapy also against solid tumors
Alliance for Cancer Gene Therapy announces Summit 2021 be there when the next breakthroughs happens
Join world renowned cancer researchers as they gather to discuss latest advances in cancer cell and gene therapy for solid tumors
CHOP researchers find ribosome assembly essential for stem cell regeneration
Findings enhance our understanding of the importance of ribosome assembly in stem cell regeneration and potential therapeutic strategies for ribosomopathies, which lead to pediatric bone marrow abnormalities
Discovery of new protein with an important role in atherosclerosis
Atherosclerosis is the underlying condition that causes heart attacks and strokes. Researchers at Radboudumc in the Netherlands have discovered a protein that appears to play an important role in atherosclerosis. The protein is called Prosaposin, and its role in atherosclerosis…
Time needed to sequence key molecules could be reduced from years to minutes
Research demonstrates potential for rapid, accurate glycan sequencing
Study contributes to evidence for potential association between blood group a and COVID-19
As researchers around the world work to identify and address risk factors for severe COVID-19, there is additional evidence that certain blood types could be associated with greater risk of contracting the disease. A new Blood Advances study details one…
New NCCN guidelines for histiocytosis clarify best practices for recently-defined cancers
New clinical practice guidelines from National Comprehensive Cancer Network focus on workup and management for three main adult histiocytic disorders.
Protein kinases significantly contribute to the immunodeficiency in HIV patients
Researchers determine the reason for the ineffectiveness of current drug therapies in restoring the immune system of some HIV patients
CAR T-cell therapy generates lasting remissions in patients with multiple myeloma
In the KarMMa trial, ide-cel produces remissions in almost 75% of patients who had relapsed after several previous treatments; Trial results spur application for FDA approval of therapy for patients with relapsed/resistant myeloma
Measuring hemoglobin levels with AI microscope, microfluidic chips
A chip-based, microfluidic, AI-powered diagnostic platform could make medical diagnostics more affordable, accessible.
Hydrogel promotes wound healing better than traditional bandages, gauzes
Advances in hydrogel wound dressings make them antibacterial, biodegradable, better suited for healing irregular, deep wounds
New classification of leukemia subtypes reveals potential of existing drugs
Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML) – called NPM1 – that could help predict survival and improve treatment response for patients whose leukemic…
A new strategy to destroy cancer cells using magnetic nanoparticles and fields
Scientists offered a new method for treating leukemia using nanomaterials
Biomarkers that could help determine who’s at risk for severe COVID-19 symptoms
One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage. Now, researchers reporting in ACS’ Analytical Chemistry have used a combination of…
An end to invasive biopsies?
Hebrew University researchers advance simple and inexpensive diagnostic blood test
Wellcome grants €1.3M to RCSI to develop prognostic blood test for psychotic disorders
RCSI University of Medicine and Health Sciences has received a €1.3 million grant from Wellcome to further develop a blood test that can predict whether a person is likely to develop a psychotic disorder years later. The researchers had previously…
Preventive anti-clotting therapy does not boost survival of critically ill COVID patients
Among 3,239 critically ill adults with COVID-19, early use of therapeutic anticoagulation in the intensive care unit did not reduce the risk of death, an observational study found
Researchers develop 10-minute COVID-19 diagnostic test that wage workers can afford
Technology based on nanoparticles identifies IgG antibodies and costs only about a fifth of similar devices now on the market. It was developed by scientists at the University of São Paulo and Brazilian startup Biolinker.
USPSTF recommends against screening for asymptomatic carotid artery stenosis in general population
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against screening for asymptomatic carotid artery stenosis in the general adult population. Carotid artery stenosis is the narrowing of arteries that supply blood to the brain. This recommendation applies to adults…
Dementia rates higher in men with common genetic disorder haemochromatosis
New research has found that men who have the Western world’s most common genetic disorder are more likely to develop dementia, compared to those without the faulty genes. Researchers at the University of Exeter and the University of Connecticut have…
A potentially safer, more effective gene therapy vector for blood disorders
New preclinical study shows vector results in significantly more hemoglobin production than vectors currently used in gene therapy for sickle cell disease and beta-thalassemia
Assessment of maternal, neonatal cord blood SARS-CoV-2 antibodies, placental transfer ratios
What The Study Did: Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent…
Two Anti-viral Enzymes Transform Pre-Leukemia Stem Cells into Leukemia
Viral infections and space travel similarly trigger inflammation and the enzymes APOBEC3C and ADAR1; UC San Diego researchers are developing ways to inhibit them as a means to potentially lower cancer risk for both astronauts and people on Earth.
Designer DNA Therapeutic Wipes Out Cancer Stem Cells, Treats Multiple Myeloma in Mice
UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent — an antisense oligonucleotide that targets a gene called IRF4 — in patients with multiple myeloma.
New insights into wound healing process
For the first time, scientists watch fibroblasts, key cell type involved in wound healing, coordinate closure of damaged vascularized tissue
Organizations collaborate to develop international von Willebrand Disease guidelines
The American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH) have developed joint clinical practice guidelines on the diagnosis and management of von Willebrand Disease (VWD),…
New resource for survivors from NCCN helps guide life after cancer diagnosis and treatment
New NCCN guidelines for patients: Survivorship series provides expert advice to help cancer survivors sustain better health while monitoring for any long-term side effects or recurrences
An explanation for the lack of blood oxygenation detected in many COVID-19 patients
One of the physiopathological characteristics of COVID-19 that has most baffled the scientific and medical community is what is known as “silent hypoxemia” or “happy hypoxia”.