English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduWhat The Study Did: Researchers looked at whether exposure to adverse experiences, stress, and violence among 1,400 children in the United Kingdom was associated at age 18 with elevated levels in the blood of an indicator of chronic inflammation. To…
Tag: Hematology
Transient wave of hematopoietic stem cell production in late fetuses and young adults
Hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ones in patients suffering from blood related…
Published a clinical guide for the genomic diagnosis of Myelodysplastic Syndromes and Chronic Myelomonocytic leukaemia
In Spain, a workgroup of more than 400 researchers, the Spanish Group of Myelodysplastic Syndromes (GESMD), meets twice a year to present projects and undertake collaborations that improve their work in the fight against Myelodysplastic Syndromes (SMD) and Chronic Myelomonocytic…
Investigating childhood stress association with blood indicator of chronic inflammation
What The Study Did: Researchers looked at whether exposure to adverse experiences, stress, and violence among 1,400 children in the United Kingdom was associated at age 18 with elevated levels in the blood of an indicator of chronic inflammation. To…
Pattern of hospital visits offers clue to spotting people at risk of myeloma
Glasgow, UK: A condition that can progress to myeloma could be identified in patients by their unusually frequent hospital visits, according to research presented at the 2019 NCRI Cancer Conference. The study found that people with a pre-cancerous blood condition…
Scientists Find Molecular Key to Body Making Healthy T Cells
In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.
Women with anemia twice as likely to need transfusion after cesarean delivery
Screening all pregnant women for iron deficiency would enable preventive treatment
Study finds racial disparities in treatment of multiple myeloma patients
Compared with whites, African-Americans and Hispanics receive treatment later and with higher associated costs
Dr. Manel Esteller is recognized by Stanford University for its scientific impact worldwide
Dr. Manel Esteller, director of the Josep Carreras Leukemia Research Institute, is recognized by Stanford University for its scientific impact worldwide
Aggressive and agitated behaviors in dementia are better treated without medications
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine . The summaries are not intended to substitute for the full articles as a source of information. 1. Aggressive and…
Study questions ‘cross-transfer’ benefits of special exercise technique
A paper recently published by researchers from the Ohio Musculoskeletal and Neurological Institute (OMNI) at the Heritage College of Osteopathic Medicine questions the effectiveness of a patented exercise system for relieving lower back pain. In a study published in the…
Viagra helps mobilize bone marrow stem cells for transplantation in mice
The combination of two clinically approved drugs–Viagra and Plerixafor–rapidly and efficiently mobilizes blood stem cells from the bone marrow into the bloodstream in mice, researchers report October 10th in the journal Stem Cell Reports . This strategy is almost as…
Social determinant screening useful for families with pediatric sickle cell disease
Individuals with sickle cell disease (SCD) face the burdens of chronic illness and often racial disparities, both of which may increase vulnerability to adverse social determinants of health (SDoH). For children with SCD, living in poverty is associated with lower…
Study: Ibrutinib linked to high blood pressure and other heart problems
Hypertension with ibrutinib more common than previously reported; this study is first to show association between cancer drug-related hypertension and other heart problems
NIH researchers create new viral vector for improved gene therapy in sickle cell disease
‘Forward-oriented’ design might boost treatment effectiveness and broaden use
For the first time, UMD professor observes crystallized iron product, hemozoin, made in mammals
Findings could be used to treat sickle cell disease and malaria patients, while opening up diverse research avenues across immunology, parasitology, neuroscience, microbiology, and even urology
New blood test capable of detecting multiple types of cancer
In study, test proved able to detect and localize more than 20 types of cancer with a high degree of accuracy; Test detected methylation patterns associated with cancer in free-floating DNA in blood
Discovery could improve MDS cancer treatment
Myelodysplastic syndrome (MDS), one of the most common blood cancers, has very few treatment options. Now, researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new and promising drug target for this deadly condition. “At the moment, only a…
A mouse or an elephant: what species fights infection more effectively?
Hamilton College researcher reveals body size shapes mammal immune defenses
Exploring the risk of ALL in children with Down syndrome
Acute lymphoblastic leukemia (ALL), is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL than children without Down syndrome. Historically, children with Down syndrome and ALL had more…
Cellular senescence is associated with age-related blood clots
Cells that become senescent irrevocably stop dividing under stress, spewing out a mix of inflammatory proteins that lead to chronic inflammation as more and more of the cells accumulate over time. Publishing in the September 24 edition of Cell Reports…
Discovery of novel cancer signaling mechanism and design of new anticancer compound
Using a newly synthesized compound and advanced immunofluorescence techniques, scientists uncover novel signaling mechanism in cancer and also propose new channel of treatment
Better samples, better science: new study explores integrity of research specimens
Effective diagnosis and treatment of disease draws on painstaking research, which often relies on biological samples. The avalanche of studies used to better understand illnesses and design effective therapies cost billions of dollars and potentially affects millions of lives. So,…
Changes in internal medicine subspecialty choices of women, men
What The Study Did: This study used enrollment data to examine changes in the internal medicine subspecialty choices of women and men from 1991 to 2016. Data were examined for nine internal medicine subspecialties: cardiovascular disease, endocrinology, gastroenterology, geriatric medicine,…
TropMed19: Research findings on Ebola, monkey malaria, tick-borne diseases, disease-fighting AI and more
Neonatal health pioneers, Abhay and Rani Bang, to deliver keynote; authors Richard Preston and Douglas Preston to talk infectious disease
Pain Clinic Provides Safe Space for Sickle Cell Patients to Receive Treatment
With the aim of improving pain control and decreasing hospitalizations for vaso-occlusive crisis, the Sickle Cell Team at Children’s of Alabama is moving to implement individualized pain plans for patients and pilot an outpatient pain clinic.
Dana-Farber receives $5 million gift to create the Edward P. Evans Center for MDS
Largest single philanthropic commitment to MDS research and care in Dana-Farber history
Cancer Predisposition Clinic Aims To Change Trajectory Of Genetically Based Cancer
Children’s of Alabama’s Cancer Predisposition Clinic physicians develop personalized screening for children who have inherited cancer predisposition syndromes with hopes that early detection will lead to improved outcomes.
Australian immunology pioneer Jacques Miller wins Lasker Award
Emeritus Professor Jacques Miller AC from Melbourne’s Walter and Eliza Hall Institute has won a Lasker Award, one of the highest international honours in medical research. Professor Miller was joint recipient of the 2019 Albert Lasker Basic Medical Research Award…
Cancer cells ‘corrupt’ their healthy neighbors
The healthy cells immediately surrounding a tumor become more stem cell-like and support cancer grow
Computer model could help test new sickle cell drugs
PROVIDENCE, R.I. [Brown University] — A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances…