In this study, the Sánchez Alvarado Lab shows that whole-body regeneration involves transcriptional changes in cells from all three germ layers (muscle, epidermis, and intestine) of the body, and that tissue from areas distant from, as well as nearby to the site of injury, contribute to the process of regeneration.
Its powers may not rival Wolverine’s, but a regenerative implant engineered by researchers at the University of Nebraska Medical Center and University of Nebraska–Lincoln could help repair bone-deep damage following physical trauma, surgery or osteoporosis.
Why are “ghost forests” filled with dead trees expanding along the mid-Atlantic and southern New England coast? Higher groundwater levels linked to sea-level rise and increased flooding from storm surges and very high tides are likely the most important factors, according to a Rutgers study on the impacts of climate change that suggests how to enhance land-use planning.
David Kaplan, the Stern Family Professor of Engineering at Tufts University School of Engineering, has been elected to the National Academy of Engineering in recognition of his contributions to silk-based materials for tissue engineering and regenerative medicine.
Working with fish, birds and mice, Johns Hopkins Medicine researchers report new evidence that some animals’ natural capacity to regrow neurons is not missing, but is instead inactivated in mammals. Specifically, the researchers found that some genetic pathways that allow many fish and other cold-blooded animals to repair specialized eye neurons after injury remain present in mammals as well, but are turned off, blocking regeneration and healing.
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A new study published in the Proceedings of the Royal Society B from researchers at the University of Chicago and Universidade Federal do Pará explores regenerative ability in the tails of West African lungfish for the first time, and finds that the process shares many of the same traits as tail regeneration in salamanders. Their results indicate that this trait was likely found in a common ancestor – and provide a new opportunity for better understanding and harnessing the mechanisms of limb regrowth.
Researchers have identified a microRNA (miRNA) that could promote hair regeneration. This miRNA – miR-218-5p – plays an important role in regulating the pathway involved in follicle regeneration, and could be a candidate for future drug development.
University of Pittsburgh researchers have created a biodegradable nerve guide – a polymer tube – filled with growth-promoting protein that can regenerate long sections of damaged nerves, without the need for transplanting stem cells or a donor nerve.