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Nanobowls serve up chemotherapy drugs to cancer cells

May 20, 2020 sarah Jonas Drug Delivery, drug delivery vehicle

For decades, scientists have explored the use of liposomes –– hollow spheres made of lipid bilayers –– to deliver chemotherapy drugs to tumor cells. Now, researchers report in ACS’ Nano Letters a way to stabilize liposomes by embedding a stiff nanobowl in their inner cavity.

Research Results

UTEP Researchers Develop Nanohybrid Vehicle to Optimally Deliver Drugs Into the Human Body

April 23, 2020 sarah Jonas BIOCHEMISTRY, Biomedical Research, drug delivery vehicle, Oxidative Stress

The researchers discovered that encapsulating ellagic acid in chitosan, a sugar, reduces its inherent cytotoxicity while enhancing its anti-oxidant properties. The chitosan shell, which makes up the hard outer skeleton of shellfish, also permits EA delivery via a rapid burst phase and a relatively slow phase.