Potential drug treats fatty liver disease in animal models, brings hope for first human treatment

A potential drug successfully treats the severe form of nonalcoholic fatty liver disease in non-human primates — bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests. Nonalcoholic steatohepatitis (NASH) causes scarring and inflammation in the liver and is estimated to affect up to 6.5% of the global population.

WormAtlas expanding beyond C. elegans with support from NIH

The National Institutes of Health recently pledged $2.6 million towards the Center for C. elegans Anatomy, also known as WormAtlas. The center provides anatomical resources for researchers studying C. elegans, the tiny nematode worm that serves as a model organism for higher animals, including humans. Of the total award, $950,000 goes to co-principal investigator Nathan Schroeder of the University of Illinois College of Agricultural, Consumer and Environmental Sciences (ACES).

Apes show dramatically different early immune responses compared to monkeys

A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions.