Researchers Design Multiclass Cancer Diagnostic Tool Using AI, MicroRNA

MicroRNAs, or miRNAs, regulate genes and biological processes in the human body, including cancer formation and development. To explore the feasibility of miRNAs as cancer biomarkers, researchers created a multiclass cancer diagnostic model using miRNA expression profiles. The study examined the relationship between the composition of miRNAs and various types of cancers. Findings suggest that miRNAs may be highly unique to specific cancerous tissues and can be strong biomarkers for detection and classification in both research and the clinical field

MD Anderson Research Highlights for June 7, 2023

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

Targeting microRNAs could unmask hidden vulnerability in breast cancer stem cells

Researchers in Italy have identified a pair of microRNA molecules that help maintain a population of cancerous stem cells that drive the growth of breast cancers and initiate tumor relapse after treatment. The study, which will be published April 2 in the Journal of Cell Biology (JCB), reveals that targeting these microRNAs makes cancer stem cells more susceptible to some chemotherapies and could potentially improve the prognosis of patients with aggressive forms of breast cancer.