sciencenewsnet.in

RUDN pharmacists proposed ways to increase the activity of levofloxacin and overcome bacterial resistance to antimicrobial agents

February 21, 2024 sarah JonasResearch Results

RUDN University pharmacists modeled derivative molecules of the antibacterial levofloxacin to find out what biological functions its individual structural fragments – pharmacophores – are responsible for. This is necessary to increase the effectiveness of the drug, as bacteria become increasingly resistant to antibiotics.

Combination therapy overcomes BET inhibitor resistance

April 10, 2023 sarah JonasResearch Results

St. Jude Children’s Research Hospital scientists developed a combination therapy for a leukemia subtype harboring rearrangements in the KMT2A gene. The approach overcomes the cancer’s drug resistance, without adding toxicity. The study appears in Proceedings of the National Academy of Science.

Global oncology pharmacists face restricted access to essential PPE items, UCI study finds

June 8, 2020 sarah JonasResearch Results

Oncology pharmacy practitioners around the globe are fighting to provide cancer patients high quality cancer care with increasingly limited and sometimes restricted personal protective equipment supply as well as impaired access to essential anticancer medication, according to University of California, Irvine-led study.