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UrduIn this new supplement to the Journal of Parkinson’s Disease experts report on how digital technology is being used to reshape research and clinical care in Parkinson’s disease
Tag: Parkinson’s Disease
Chemists Found an Effective Remedy For “Aged” Brain Diseases
Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies.
A Trojan horse could help get drugs past our brain’s tough border patrol
Sclerosis, Parkinson’s Disease, Alzheimer’s and epilepsy are but a few of the central nervous system disorders. They are also very difficult to treat, since the brain is protected by the blood-brain barrier. The blood-brain barrier works as a border wall…
UCPH researchers prove powerhouse malfunction as the major cause of Parkinson’s Disease
12,000 people in Denmark and 7 to 10 million people worldwide suffer from Parkinson’s Disease (PD). It is the second most common neurogenerative disorder of aging and the most common movement disorder, but the cause of the disease is largely…
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration.
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
A new study published in Brain Sciences today, shows patients with mild-to-moderate Parkinson’s disease (PD) can slow the progress of the disease by participating in dance training with music for one-and-a-quarter hours per week.
New Alzheimer’s treatment targets identified
A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs with therapeutic potential.
Brain mapping method illuminates targets for treating neuropsychiatric symptoms
Novel approach finds targets for future clinical trials in depression and Parkinson’s disease
Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis
Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration. For this study, it has been used dopaminergic neurons differentiated from patient stem cells as a…
Dancing with music can halt most debilitating symptoms of Parkinson’s disease
First-of-its-kind York U study shows participating in weekly dance training improves daily living and motor function for those with mild-to-moderate Parkinson’s
Adult ADHD is linked to numerous physical conditions
Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry . “Identifying…
Engineered Neural Networks Help ID Responses Associated with Abnormalities in Parkinson’s Disease
Article title: Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks Authors: Vibeke D. Valderhaug, Kristine Heiney, Ola Huse Ramstad, Geir Bråthen, Wei-Li Kuan, Stefano Nichele, Axel Sandvig, Ioanna Sandvig From the authors: “In this study, we investigate the…
Discovery of nanosized molecules that might inhibit Alzheimer’s and Parkinson’s diseases
Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues.
Discovery of nanosized molecules that might inhibit Alzheimer’s and Parkinson’s diseases
Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues. This new discovery by researchers at Umeå University, Sweden, in collaboration with researchers in Croatia and Lithuania, provides renewed hope for novel treatments…
Henry Ford Health System Therapeutic Choir Finds Its Voice Through COVID-19
DETROIT – Henry Ford Health System is using the healing power of singing to help patients with voice disorders that result from various medical conditions such as Parkinson’s disease, stroke and vocal cord paralysis to help improve their voices. Patients in a therapeutic choir called the Motor City Upbeats regain their vocal strength and range and breathing through a series of simple exercises and techniques taught in a welcoming, cheerful environment where just hearing the sound of your voice is music to the ears.
Will reduction in tau protein protect against Parkinson’s and Lewy body dementias?
A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.
The ISSCR 2021 Annual Meeting starts 21 June
Six days of exceptional stem cell science
Alzheimer disease research results over-hyped if science papers omit mice from the title
Scientists call for accurate reporting of animal studies to avoid misleading the public with exaggerated news headlines
Two decade analysis of African neuroscience research prompts calls for greater support
With the world’s largest human genetic diversity, experts believe Africa is vital to help progress neuroscience research
New study gives clue to the cause, and possible treatment of Parkinson’s Disease
Zebrafish model research reveals clues about molecular triggers of Parkinson’s Disease
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche. The study, published in…
Understanding gut inflammation may hold clues to mitigating Parkinson’s onset
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.
Simple blood test can accurately reveal underlying neurodegeneration
A single biomarker can accurately indicate the presence of underlying neurodegeneration in people with cognitive issues
The Mathematical Model of the Mind
‘A must read for anyone interested in theoretical studies of cortical microcircuits’
Studies reveal skull as unexpected source of brain immunity
Immune cells from skull bone marrow guard the brain, spinal cord
After 15 Years, Deep Brain Stimulation Still Effective in People with Parkinson’s
Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that compared to before deep brain stimulation, study participants continued to experience significant improvement in motor symptoms, which are symptoms that affect movement, as well as a reduction in medications 15 years later.
Deciphering Gene-Environment Interactions in Parkinson’s Disease
The interaction between an individual’s genetics and their local environment plays a critical role in an individual’s likelihood of getting Parkinson’s disease. In this perspective, researchers highlight how a common fly could be used to better understand the complex interactions…
After 15 years, deep brain stimulation still effective in people with Parkinson’s
MINNEAPOLIS – Deep brain stimulation continues to be effective in people with Parkinson’s disease 15 years after the device is implanted, according to a study published in the June 2, 2021, online issue of Neurology® , the medical journal of…
New algorithm could help enable next-generation deep brain stimulation devices
PROVIDENCE, R.I. [Brown University] — By delivering small electrical pulses directly to the brain, deep brain stimulation (DBS) can ease tremors associated with Parkinson’s disease or help relieve chronic pain. The technique works well for many patients, but researchers would…
Role of sleep-related brain activity in clearing toxic proteins and preventing Alzheimer’s disease
Global brain activity seen on fMRI, and its connection with cerebrospinal fluid flow weaker in brains of individuals with Alzheimer’s disease risk or related toxin buildup
Novel nano-encapsulation approach for efficient dopamine delivery in Parkinson’s treatment
Parkinson’s disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters…
Modulating rapamycin target protein promotes autophagy, lowering toxic Huntingtin protein
Experiments with small molecule have implications for research on aging.
Changes in how cholesterol breaks down in the body may accelerate progression of dementia
Study suggests that some cholesterol medications may impact signaling pathways in the brain, particularly in men
Discovery may point to Parkinson’s disease therapies
University of Guelph researchers have discovered a key way Parkinson’s disease spreads in the brain
Novel approaches in treating neurodegenerative disorders
The central nervous system (CNS) is the most vital component of our body, regulating various kinds of daily activities that are essential for our life processes. Keeping the balance between body and brain and maintaining the homeostasis of CNS is…
Low blood flow in the brain may be an early sign of Parkinson’s disease
Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue.
Impaired dopamine transporters contribute to Parkinson’s disease-like symptoms
A rare mutation that causes Parkinson’s disease-like symptoms interrupts the flow of dopamine in the brain, suggests a study in fruit flies published today in eLife.
Low blood flow in the brain may be an early sign of Parkinson’s disease
Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. In the long term, this may cause symptoms of Parkinson’s disease.
Impaired dopamine transporters contribute to Parkinson’s disease-like symptoms
A rare mutation that causes a Parkinson’s disease-like disorder in young children interferes with dopamine transporters in the brain, suggesting that treatments targeting the transporters may be beneficial.
American College of Sports Medicine and Parkinson’s Foundation Announce Exercise Recommendations for Parkinson’s Disease
ACSM and the Parkinson’s Foundation released new exercise recommendations to provide safe and effective guidance on physical activity to people with Parkinson’s and to certified exercise professionals working with them.
Step-closer to nasal spray drug delivery for Parkinson’s disease
Scientists at the University of York have made significant progress in the development of a nasal spray treatment for patients with Parkinson’s disease. Researchers have developed a new gel that can adhere to tissue inside the nose alongside the drug…
Parkinson’s patients are particularly affected by COVID-19
A reason for these findings could be due to the fact that Parkinson’s patients often also have many risk factors for a severe course of Covid-19.
Parkinson’s patients are particularly affected by COVID-19
Healthcare research
Protein simulation, experiments unveil clues on origins of Parkinson’s disease
HERSHEY, Pa. — Parkinson’s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew…
Fresh insight into protein production inside brain cells could help tackle Parkinson’s
Wednesday 19 May 2021 – New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.…
New insight into protein production in brain could help tackle dementia
Peer-reviewed | experimental study | animals and cells
Researchers wirelessly record human brain activity during normal life activities
NIH BRAIN Initiative-funded study opens the door to correlating deep brain activity and behavior
Scientists find small molecule cocktail to improve stem cell use in research, medicine
Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function. The researchers suggest that the…
Awakening ‘ghosts’ in patients with Parkinson’s, a powerful diagnostic tool
“We’re developing something similar to a cardiac stress test, but instead of testing the heart, we’re testing the brain,” says EPFL neuroscientist Olaf Blanke. EPFL scientists are providing a new way to evaluate the onset of hallucinations in patients with…
Study says inflammation seen in earliest stages of Parkinson’s disease, and it is different between men and women
New research shows evidence of inflammation in the blood of Parkinson’s disease patients during the earliest stages of the disease, lending support to theories that inflammation is a major driver of PD. The study also points out differences between the sexes in the symptoms and course of the disease.