English
Arabic
Chinese (Simplified)
Dutch
Esperanto
French
German
Greek
Italian
Japanese
Korean
Portuguese
Russian
Spanish
UrduArticle title: Age-associated differences in the human lung extracellular matrix Authors: Maunick Lefin Koloko Ngassie, Maaike de Vries, Theo Borghuis, Wim Timens, Don D. Sin, David Nickle, Philippe Joubert, Peter Horvatovich, György Marko-Varga, Jacob J. Teske, Judith M. Vonk, Reinoud…
Tag: Aging
Sasin Professor Speaks at TED2023 Session 3: “Leaping Boldly into New Global Realities”
Asst. Prof. Dr. Piyachart Phiromswad, Assistant Director for Academic Affairs, Director of the Ph.D. program and a faculty member in Finance at Sasin Graduate Institute of Business Administration of Chulalongkorn University, was one of the speakers for TED2023 Session 3: “Leaping boldly into new global realities” on Tuesday, April 18, 2023 at the Vancouver Convention Centre, Vancouver, BC, Canada.
ENDO 2023 press conferences to highlight emerging technology and diabetes research
Researchers will delve into the latest research in diabetes, obesity, reproductive health and other aspects of endocrinology during the Endocrine Society’s ENDO 2023 news conferences June 15-18.
Running Throughout Middle Age Keeps ‘Old’ Adult-born Neurons ‘Wired’
A new study provides novel insight into the benefits of exercise, which should motivate adults to keep moving throughout their lifetime, especially during middle age. Long-term exercise profoundly benefits the aging brain and may prevent aging-related memory function decline by increasing the survival and modifying the network of the adult-born neurons born during early adulthood, and thereby facilitating their participation in cognitive processes.
Decrease Oxygen to Boost Longevity?
Living in a low-oxygen environment extended life spans, preserved neurologic function in mice.
Blood Flow-restricted Resistance Exercise Could Help Counteract Age-related Muscle Loss
Low-load blood flow-restricted resistance exercise helped counter age-related muscle decay “with a modest exercise volume and in a very time-efficient manner.” The study is published ahead of print in the Journal of Applied Physiology. It was chosen as an APSselect article for May.
Poor sleep can lead to long-term health problems for older adults, UTSW specialists say
It’s a common misconception that older adults need less sleep than those younger, but many get fewer hours due to insomnia and various health problems, including sleep apnea and heart trouble. In addition to a reduced quality of life, long-term health consequences of poor sleep include high blood pressure, weight gain, stroke, heart attack, diabetes, memory problems, and even increased risk of death, said Deborah Freeland, M.D., Assistant Professor of Internal Medicine and a member of UTSW’s Division of Geriatric Medicine.
Women Have Less Age-related Decrease of Gray Matter in Brain than Men
Article title: Differential reduction of gray matter volume with age in 35 cortical areas in men (more) and women (less) Authors: Peka Christova and Apostolos P. Georgopoulos From the authors: “This study showed an overall decrease of cortical gray matter…
Renowned Expert on Aging and Brain Health Available to Comment on Study Finding Regular Internet Usage Associated with Decreased Risk of Dementia
A new study by NYU School of Global Health published in the Journal of the American Geriatrics Society reports that regular Internet usage was associated with approximately half the risk of dementia compared to non-regular usage.
Male, female knee cartilage disparities may explain differences in rates of degeneration
Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical Center point to biological differences in the knee cartilage of male and female animals that could explain substantial variances in rates of osteoarthritis between the sexes and may eventually lead to tailored treatments that take these into account.
URI business professor, colleagues look at mortality and leadership succession in family business
By 2030, more than 30% of family businesses in the U.S. will lose their aging leaders to retirement, or death. Many of those leaders don’t have a strategy for letting go of their business, turning it over to a successor, or selling it. While it is rare for an incumbent leader to die while in office, it is difficult for them to face their mortality.
Osteoporosis treatments may benefit from discovery of key driver of low bone density
Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis.
AI can spot early signs of Alzheimer’s in speech patterns, study shows
New technologies that can capture subtle changes in a patient’s voice may help physicians diagnose cognitive impairment and Alzheimer’s disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer’s Association publication Diagnosis, Assessment & Disease Monitoring.
Awareness vital to improving Parkinson’s patients’ quality of life, UTSW neurologist says
About 1 million people in the United States have Parkinson’s disease, a progressive neurological disorder that ranks second to Alzheimer’s among the most common neurodegenerative diseases. While many tend to associate Parkinson’s with hand tremors, it can cause a broad range of symptoms, affecting both motor and nonmotor functions.
Study reveals that bats experience hearing loss in old age
Many mammals suffer hearing loss in old age, but bats were thought to be immune to this phenomenon because of the importance of hearing for echolocation. However, researchers in Israel have discovered that bats lose their hearing in old age just like humans do.
Machine learning models rank predictive risks for Alzheimer’s disease
Once adults reach age 65, the threshold age for the onset of Alzheimer’s disease, the extent of their genetic risk may outweigh age as a predictor of whether they will develop the fatal brain disorder, a new study suggests.
New form of omega-3 could prevent visual decline with Alzheimer’s disease
For the first time, researchers have developed a form of the omega-3 fatty acid docosahexaenoic acid (DHA) that is capable of crossing into the eye’s retina to ward off visual declines related to Alzheimer’s disease, diabetes and other disorders.
To Ward Off Aging, Stem Cells Must Take Out the Trash
UC San Diego researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders.
Does discrimination accelerate aging in African American cancer survivors?
Cancer and its treatment can accelerate the rate of aging because they both destabilize and damage biological systems in the body.
On pandemic’s third anniversary, loneliness and isolation are down, but still high, among older adults
After three years of pandemic living, loneliness, isolation and lack of social contact have finally started to decline among older adults, a new poll shows.
Heart Tissue Heads to Space to Aid Research on Aging and Impact of Long Spaceflights
Johns Hopkins Medicine researchers are collaborating with NASA to send human heart “tissue-on-a-chip” specimens into space as early as March. The project is designed to monitor the tissue for changes in heart muscle cells’ mitochondria (their power supply) and ability to contract in low-gravity conditions.
UC San Diego’s Astrobiotechnology Hub to Drive Drug Discovery in Space
UC San Diego’s new Astrobiotechnology Hub brings together leaders in academia, biotechnology and aerospace industries under a united mission to advance stem cell science and commercialization in space.
Scientists Discover New Protein Activity in Telomeres
Reporting in the PNAS, UNC School of Medicine researchers made the stunning discovery that telomeres contain genetic information to produce two small proteins, one of which they found is elevated in some human cancer cells, as well as cells from patients suffering from telomere-related defects.
A New Strategy for Repairing DNA Damage in Neurons
Researchers discover a mechanism used by neurons to repair damage that occurs during neuronal activity
Coconut Sugar May Lower Blood Pressure, Artery Stiffness in Older Adults
A first-of-its-kind study finds a natural coconut sugar may help reduce the risk of cardiovascular disease by improving blood vessel health and managing high blood pressure. The study is published ahead of print in the Journal of Applied Physiology.
Stay alert to avoid falls that can cause serious injuries, UT Southwestern orthopedist says
Slipping on ice or tripping over a curb can result in broken bones or more serious injuries. To avoid taking an unexpected tumble, it’s important to be aware of your surroundings and watch where you’re walking, a UT Southwestern Medical Center orthopedist advises.
Study finds large gap in breast cancer treatment recommendations for patients aged 70 vs 69
Age-based heuristics can lead to large differences in breast cancer treatment based on small differences in chronologic age, according to a new analysis of more than 500,000 patient records. Patients aged 70 were nearly twice as likely to be passed over for standard-of-care radiation as those aged 69. There were no similar gaps between other age pairs. The study is among the first to demonstrate an age cutoff heuristic in oncology.
Lifespan increasing drug with potential for healthier ageing
Long-term treatment of healthy middle-aged mice with a cancer drug increases lifespan by 10% on average, equivalent to 3 years.
More Steps, Moderate Physical Activity Cuts Dementia, Cognitive Impairment Risk
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.
Researchers Find That Brains With More Vitamin D Function Better
Researchers at Tufts University have completed the first study examining levels of vitamin D in brain tissue, specifically in adults who suffered from varying rates of cognitive decline. They found that members of this group with higher levels of vitamin D in their brains had better cognitive function.
Severe COVID-19 Linked with Molecular Signatures of Brain Aging, Researchers Find
In a series of experiments, scientists found that gene usage in the brains of patients with COVID-19 is similar to those observed in aging brains.
COVID-19 vaccine’s effectiveness diminishes with age, research shows
The Pfizer-BioNTech COVID-19 vaccine limits transmission, hospitalization, and death from COVID-19 even among patients infected by variants of the virus, but the effectiveness of antibodies it generates diminishes as patients get older, according to a study by UT Southwestern researchers.
UC San Diego Sanford Stem Cell Institute Launches Stem Cells Into Space
The UC San Diego Sanford Stem Cell Institute leads its first space launch, sending stem cells into space aboard the International Space Station. The NASA-partnered study will take advantage of the microgravity environment of space to study accelerated aging in stem cells.
How to Handle the Challenges of Caring for Your Aging Parent
As a clinical social worker, Natasha Mosby has counseled family members on both sides of the spectrum: the caretakers and their aging parents. Both groups want to understand how to navigate their reversal of roles as they progress into this new chapter of their lives.
A link between lethal childhood disease and age-related muscle decline
Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy may enable development of therapies to curb the muscle decline that accompanies aging, new research suggests.
Cellular housekeeping process implicated in fatal neurological disorder
A new study from Washington University School of Medicine in St. Louis indicates that as patients age, Huntington’s disease gradually impairs autophagy, which eliminates waste from cells. This housekeeping is significant because a buildup of waste in a specific kind of neuron leads to such cells’ untimely deaths. The researchers also showed that enhancing the autophagy pathway in such neurons that were created from skin cells of Huntington’s patients protects those cells from dying.
Aging and Multiple Sclerosis
In a Lancet Neurology review, UC San Diego Health neurologist Jennifer Graves, MD, and colleagues explore the inextricable association between aging and multiple sclerosis — a chronic disease of the brain and spinal cord that changes in nature and severity…
CDC grant spurs research for fall prevention
With a $1 million grant from the CDC, ISU researchers and community partners will be the first to directly evaluate a walking program’s potential for reducing the risk and incidence of falling, which is the leading cause of injuries among people ages 65 and older in the U.S.
Sex Differences in Aging Include Varied Gene Expression, Splicing Changes
Article title: Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging Authors: Yu Han, Sara A. Wennersten, Julianna M. Wright, R. W. Ludwig, Edward Lau, Maggie P. Y. Lam From the authors: “In summary, this study shows that…
Alzheimer’s Association Awards Grant to Wake Forest University School of Medicine for Alzheimer’s Research
The Alzheimer’s Association, through its Part the Cloud global research grant program, has awarded Wake Forest University School of Medicine $795,000 over two years to study potential treatments for Alzheimer’s disease.
UCI is key member of multi-institutional, $126 million NIH brain mapping project
Irvine, Calif., Sept. 22, 2022 – The University of California, Irvine will participate in a five-year, multi-institutional, $126 million grant from the National Institutes of Health supporting the BRAIN Initiative Cell Atlas Network. The project aims to describe the cells that make up the human brain in unprecedented molecular detail, classifying them into more precise subtypes and pinpointing their location.
Daily Multivitamin May Improve Cognition and Possibly Protect Against Decline
New research from Wake Forest University School of Medicine shows that taking a daily supplement may improve cognition in older adults. In the study, researchers estimated that three years of multivitamin supplementation roughly translated to a 60% slowing of cognitive decline (about 1.8 years).
Wayne State University designated as age friendly
Wayne State University has been named a member of the Age-Friendly University Global Network, an innovative consortium of universities dedicated to promoting equity, inclusion and opportunity for older adults. A strategic focus of the university is diversity, equity and inclusion. The AFU designation confirms that “age” is an important dimension of that strategy.
Poll: Aching joints make older adults reach for many forms of pain relief – but health risks could follow
Popping a pill may bring short-term relief for arthritis-related joint pain, but many older adults may not realize that what they swallow could raise their risk of other health problems, or that other non-drug options could help them, a new poll suggests.
Ochsner Accountable Care Network announces sixth straight year of exceptional quality outcomes and multi-million-dollar healthcare savings
OACN’s 2021 clinical successes, highlighted by a 100% quality score, can be attributed to increasing primary care physician visits, focusing on high-risk patient care coordination and support, reducing unnecessary hospitalizations through ambulatory care coordination, and improving patient satisfaction.
Excessive blue light from our gadgets may accelerate the aging process
Excessive exposure to blue light, for example through TVs, laptops, and phones, may have an aging effect on our body, suggests a new study. It shows that the levels of specific metabolites – chemicals that are essential for cells to work correctly – are altered in the cells of fruit flies exposed to blue light.
Who’s looking out for aging doctors susceptible to cognitive decline?
Older physicians benefit from their many years of experience and the skills they have developed over decades of practice. At the same time, they may be at risk of cognitive decline, raising concerns about job performance deficits.
Peter Adams and Bing Ren awarded $10.6M to create atlas of aging cells
Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.
Having a partner more important than children to staving off loneliness during pandemic, new study finds
A new study released in the European Journal of Ageing found that having a partner had a greater impact than having children in helping to stave off loneliness among older adults during the pandemic’s first wave. Researchers at the University of Rhode Island, University of Florence, University of Maryland Baltimore County and the SGH Warsaw School of Economics analyzed data on more than 35,000 adults aged 50 and older from the Survey of Health, Ageing and Retirement in Europe to examine if unpartnered and childless older adults reported more loneliness and how that changed over the course of the pandemic.
Research links red meat intake, gut microbiome, and cardiovascular disease in older adults
A new study shows older adults who ate about a serving of meat daily had a 22 percent higher risk of cardiovascular disease than those who didn’t eat meat, and identifies biologic pathways that help explain the risk. Higher risk and links to gut bacteria were found for red meat, not poultry, eggs, or fish.