A Novel Class of Long Non-coding RNAs May Help Explain Increased Susceptibility of Females to Depression

Researchers at Mount Sinai have found that a novel class of genes known as long non-coding RNAs (lncRNAs) expressed in the brain may play a pivotal role in regulating mood and driving sex-specific susceptibility versus resilience to depression.

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Long-Term Follow-Up Data Shows Deep Brain Stimulation Is an Effective Treatment for Treatment-Resistant Depression

A study published online on Friday, October 4, in The American Journal of Psychiatry found that deep brain stimulation (DBS) of an area in the brain called the subcallosal cingulate (SCC) provides a robust antidepressant effect that is sustained over a long period of time in patients with treatment-resistant depression—the most severely depressed patients who have not responded to other treatments

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