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UrduChildren with liver transplants must take immunosuppressant medications for life. To maintain tolerance of the transplanted liver, doctors treat transplant rejection and conduct ongoing maintenance immunosuppression by increasing dosages of medication enough to counteract rejection. CHLA researchers are developing an imaging panel that identifies the cell types implicated in transplant rejection.
Tag: Liver Transplant
Mount Sinai Researchers Receive $5 Million Gift From the Blavatnik Family Foundation to Expand Revolutionary Organ Perfusion Platform
The Mount Sinai Recanati/Miller Transplantation Institute has received a $5 million gift from the Blavatnik Family Foundation, pledged across five years.
UNC Hospitals Performs First Domino Liver Transplant in Decades
Chirag Desai, MD, FACS, an abdominal organ transplant and hepatobiliary-pancreatic surgeon at UNC Hospitals, performed a “domino” liver transplant, which helped two patients from a single donor without splitting a liver.
In historic procedure, donor liver protects heart transplant
Doctors in Seattle are reporting a history-making case in which a patient received two donor organs, a liver and a heart, to prevent the extreme likelihood that her body would reject a donor heart transplanted alone. In this innovative case, the organ recipient’s own healthy liver was transplanted, domino-like, into a second patient who had advanced liver disease.
Partial Liver Transplants for Kids Key to Preventing Waitlist Deaths and Improving Outcomes
Dozens of children die each year in the U.S. while waiting for a new liver. A new analysis suggests that greater use of partial liver transplants — either from a living donor or by splitting a deceased donor’s liver for two recipients — could save many of these young lives.
The Medical Minute: Six organ donation facts knock down six myths
More than 100,000 people in the U.S. are awaiting new organs. Many won’t live long enough to get them. The new chief of transplant at Penn State Health Milton S. Hershey Medical Center debunks the myths that get between donors and recipients.
Research May Speed Identification of Patients Who Need Liver Transplants
Simple blood measurement of a short-lived protein helped predict which patients would and wouldn’t likely survive without a liver transplant, according to a Rutgers study
Monitoring Epstein-Barr viral load after liver transplant may reduce risk for rare posttransplant complication
A study of adult recipients of liver transplants has found that monitoring transplant recipients for Epstein-Barr virus viral load (EBV VL) helped to reduce risk for posttransplant lymphoproliferative disease (PTLD), a rare but serious potential complication of transplantation. The findings are published in Annals of Internal Medicine.
Program Shortens ICU Stays By 57% After Pediatric Liver Transplant
A pioneering protocol developed at Children’s Hospital Los Angeles is reducing overall opioid use, speeding rehabilitation and shortening intensive care unit (ICU) stays for pediatric liver transplant patients—including infants as young as 5 months old.
Livers have the potential to function for more than 100 years
There is a small, but growing, subset of livers that have been transplanted and have a cumulative age of more than 100 years.
Great Actions Leave a Mark campaign celebrates the Gift of Life through Living Organ Donation
UHN’s Ajmera Transplant Centre and The Centre for Living Organ Donation announce today the launch of a new campaign, Great Actions Leave a Mark, www.greatactions.ca. The campaign showcases through artistic photos and video, the stories and scars (the mark) from 39 living organ donors and transplant recipients across Canada.
Children’s Hospital Los Angeles Hosts 26th Annual Society of Pediatric Liver Transplantation Meeting
Children’s Hospital Los Angeles is hosting the 26th annual meeting of the Society of Pediatric Liver Transplantation, a multidisciplinary, multicenter consortium focused on optimizing outcomes in pediatric liver transplantation through research, advocacy and dissemination of best practices in the field.
AASLD Foundation Funds Over $1.5 Million in Hepatology Research and Career Development in 2022
The American Association for the Study of Liver Diseases (AASLD) Foundation, the largest medical society supporter of liver disease research and training in the United States, today announced its combined investment of over $1.5 million in Research and Career Development Awards, Abstract Awards, Emerging Liver Scholars (ELS) Program for medical residents and its new Emerging Liver Advanced Practice Provider (APP) Program.
The 2022 award recipients — selected from a highly competitive applicant pool — demonstrate both exceptional aptitude and deep interest in liver disease research and treatment. Their work will further advance the mission of the AASLD Foundation and hepatology as a medical specialty.
Shrinking Liver Cancer Tumors Before Transplant Yields Excellent Outcomes, Researchers Report
Treating liver cancer tumors to shrink them in order to allow the patient to qualify for a liver transplant leads to excellent 10-year post-transplant outcomes, according to new Mount Sinai research published in JAMA Surgery. The results validate current national policies around transplant eligibility.
Risk factors identified for autoimmune hepatitis after liver transplant
A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation. The findings, published in the Journal of Hepatology, represent a first step toward better managing and potentially preventing this uncommon condition.
National ‘Acuity Circles’ Policy Leads to Delays in Liver Donor Procurements
A national policy change to facilitate the broader sharing of donor livers through “acuity circles” has resulted in procurement delays, according to a researcher at the University of Miami Miller School of Medicine.
Transplants for alcohol-related liver inflammation surge during pandemic
Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.
Change in Waiting List Registration, Liver Transplant for Alcoholic Hepatitis During COVID-19
Researchers report waiting list registrations and deceased donor liver transplants in the U.S. for alcoholic hepatitis, which can develop after a short period of alcohol misuse, increased during COVID-19, exceeding volumes forecasted by pre-COVID-19 trends, while trends for alcohol-related cirrhosis and non-alcohol-associated liver disease remained unchanged.
Living Donor Liver Transplants: Better Outcomes for Children
In a worldwide pediatric study, researchers from Children’s Hospital Los Angeles show the clear benefit of using living donor liver tissue for transplants.
Study reveals Black recipients of liver transplants have lower post-transplant survival rates than white or Hispanic patients
A new study from Keck Medicine of USC reveals that Black recipients of liver transplants have lower post-transplant survival rates than white or Hispanic patients
Vanderbilt Transplant Center Reaches New Record Number of Transplants Performed
The Vanderbilt Transplant Center performed a record number of solid organ transplants in fiscal year 2021 (FY 21) — 637 life-saving procedures among its adult and pediatric programs — despite occurring entirely during the COVID-19 pandemic.
Announcing Virtual Press Conference for Experimental Biology 2021 Meeting
Reporters are invited to join a live Q&A discussion of exciting research announcements at the forefront of the life sciences during a virtual press conference for the Experimental Biology (EB) 2021 meeting. The press conference will be held online from 1–1:45 p.m. EDT on Monday, April 26, 2021 (RSVP by Friday, April 23).
Reverse-order heart-liver transplant helps prevent rejection for highly sensitized patients
Patients with high levels of antibodies face major challenges getting a transplant. These highly sensitized patients have a higher risk of death while waiting for suitable organs. But there is new hope for highly sensitized patients in need of a combined heart and liver transplant, thanks to an innovative surgical approach at Mayo Clinic.
Researcher Developing Scoring System to Redefine How U.S. Patients are Prioritized for Liver Transplant
Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are collaborating with faculty at the University of Pennsylvania to develop a risk score that more comprehensively prioritizes liver cancer patients for transplantation.
Lung, Heart, Kidney and Liver Transplant Programs Rank among Nation’s Best
UC San Diego Health’s lung, heart, kidney and liver transplant programs rank at the top nationally in the latest biannual Scientific Registry of Transplant Recipients (SRTR) report. Innovative treatment and multi-disciplinary care contribute to the high rankings for one-year survival outcomes.
Children’s Hospital Los Angeles Performs 400th Pediatric Liver Transplant
The Liver and Intestinal Transplant Program at Children’s Hospital Los Angeles began in 1998 and now performs 25 to 30 liver transplants each year—the most in Southern California—with survival rates exceeding national averages. The hospital recently performed its 400th transplant.
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Expert Alert: 5 things to know about being a living liver donor
About 1 in 5 patients who are on the national waiting list for a liver transplant die or become too sick before an organ becomes available. With an ever-growing need for organs, Mayo Clinic is working to increase awareness about living liver donation for transplantation.
UVA Children’s Opening Pediatric Liver Clinic in Richmond
UVA Children’s is opening a pediatric hepatology clinic in Richmond on Oct. 6 that will provide comprehensive care for children with liver disease, including evaluations for liver transplants.
Liver Transplant Team Part of National Trial to Increase Donor Pool
UC San Diego Health program offers comprehensive care with excellent outcomes Nationally, more than 12,000 people need a liver transplant, including more than 2,300 Californians. Patients can wait several years on the liver transplant wait list in California before receiving…
UC San Diego Health Revives Non-Beating Donor Heart for Successful Transplantation
UC San Diego Health is the first hospital on the West Coast to perform heart transplant surgery from a donor after circulatory death using a new portable organ care system. The investigational procedure could significantly decrease transplant waiting list times and improve patient outcomes.
Researchers receive $2.8 million grant to develop blood-based test for liver transplant candidate selection
Researchers from the UCLA Jonsson Comprehensive Cancer Center received a $2.8 million, five-year grant from the National Cancer Institute to help develop a blood-based test to improve the selection and prioritization for patients with liver cancer who need a liver transplantation.
Living Liver Transplant Program to Increase Availability of Organs
Vanderbilt University Medical Center is launching a living liver donor transplant program, significantly increasing the number of available organs for life-saving transplants