Investigators with Cedars-Sinai Guerin Children’s and other research institutions have identified a process responsible for the development of teeth called incisors—a discovery that could one day improve understanding of how birth defects happen.
Tag: Embryonic Development
Study: Blood stem cell diversity arises in embryonic development
All humans have a diverse set of blood stem cell types that help govern overall health. As people age, they tend to lose this diversity, increasing their risk for blood cancers, cardiovascular disease and all-causes death. Yale School of Medicine…
Computer model IDs roles of individual genes in early embryonic development
Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual. Mapping the roles of single genes in these networks is key to understanding healthy development and finding ways to regrow damaged cells and tissues. Likewise, understanding genetic errors could provide insight into birth defects, miscarriage or even cancer.
Spontaneous Mammary Neoplasia, Cannabidiol Exposure, Aryl Hydrocarbon Receptors, and More Featured in July 2021 Toxicological Sciences
Toxicological Sciences delivers the latest toxicology research in the July 2021 issue. The issue features investigations in delivers the latest toxicology research in areas such as exposure to delta-9-tetrahydrocannabinol and cannabidiol, effects of ENDS vapors on amino acid metabolism, and more.
Weizmann Institute Scientists Grow Advanced Mouse Embryos Outside the Uterus
In a first, the Weizmann Institute’s Prof. Jacob Hanna and his group have grown mouse embryos in an artificial uterus. The feat allows scientists to study the early stages of development, with potential implications that include understanding why implantations fail and the gestational conditions behind developmental disorders, as well as reduced need for laboratory animals.
Defects in developing frog brain can be prevented or repaired with bioelectric drugs
Developing frog embryo brains damaged by nicotine exposure can be repaired by treatment with ionoceutical drugs that restore bioelectric patterns in the embryo, followed by repair of normal anatomy and brain function. The research suggests therapeutic drugs may be used to help repair birth defects.
Twisting and Turning: Unraveling What Causes Asymmetry
Chirality is a type of asymmetry where something can’t overlap with its mirror image, like our hands. Michael Ostap, Ph.D., is researching what causes chirality on a molecular level to better understand embryonic development and how it can go wrong.