Amyotrophic Lateral Sclerosis (Als) | sciencenewsnet.in

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Research uncovers new insights on ALS and points to a potentially promising treatment strategy

November 10, 2021 sarah JonasResearch Results

New research provides a better understanding of the mechanisms behind the development of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, and points to a potential treatment strategy.

Researchers link neurodegenerative disease protein to defective cholesterol metabolism

August 4, 2021 sarah JonasResearch Results

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published August 4 in the Journal of Cell Biology (JCB), suggests that restoring cholesterol levels could be a new therapeutic approach for diseases associated with TDP-43, such as amyotrophic lateral sclerosis and frontotemporal dementia.