Amyotrophic Lateral Sclerosis (Als)

UC Irvine-led research team builds first tandem repeat expansions genetic reference maps

April 8, 2024 sarah JonasResearch Results

A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington’s disease and multiple cancers.

Likely next steps for Neuralink as first human trail gets underway

February 1, 2024 sarah JonasFeature

Neuralink’s brain-computer interface technology is going to be a game-changer — first for patients with paralysis and then for those with a more broad spectrum of neurological issues.

UM School of Medicine Brain and Tissue Bank to Receive $800,000 to Expand Research Initiatives and Outreach on Amyotrophic Lateral Sclerosis (ALS)

August 30, 2022 sarah JonasAnnouncement

The University of Maryland School of Medicine (UMSOM) will receive an $800,000 donation to be used by the University of Maryland Brain and Tissue Bank to advance research into the treatment and cure of Amyotrophic Lateral Sclerosis (ALS), commonly referred to as Lou Gehrig’s Disease.

First-of-its-Kind Stem Cell and Gene Therapy Highlighted at Annual Stem Cell Meeting

June 9, 2022 sarah JonasResearch Tip Sheet

Investigators from Cedars-Sinai will present the latest novel stem cell and regenerative medicine research at the International Society for Stem Cell Research (ISSCR) Annual Meeting, which is being held in person and virtually June 15-19 in San Francisco.

Research uncovers new insights on ALS and points to a potentially promising treatment strategy

November 10, 2021 sarah JonasResearch Results

New research provides a better understanding of the mechanisms behind the development of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, and points to a potential treatment strategy.

Researchers link neurodegenerative disease protein to defective cholesterol metabolism

August 4, 2021 sarah JonasResearch Results

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published August 4 in the Journal of Cell Biology (JCB), suggests that restoring cholesterol levels could be a new therapeutic approach for diseases associated with TDP-43, such as amyotrophic lateral sclerosis and frontotemporal dementia.